A5012070260- Osteoarthritis Treatment and Mechanisms
- Dental Implant Techniques and Outcomes
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Inflammatory mediators and NSAID effects
- Tendon Structure and Treatment
- Hip and Femur Fractures
- Sports injuries and prevention
- Bone Tissue Engineering Materials
- Bone Metabolism and Diseases
- Bone fractures and treatments
- Medical and Biological Ozone Research
- Biological Stains and Phytochemicals
- Research, Science, and Academia
- Knee injuries and reconstruction techniques
- Orthopaedic implants and arthroplasty
- Natural product bioactivities and synthesis
- Pharmacological Effects and Toxicity Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Mangiferin and Mango Extracts
- Orthopedic Infections and Treatments
- biodegradable polymer synthesis and properties
- Cell Adhesion Molecules Research
- Immunotherapy and Immune Responses
- Adipokines, Inflammation, and Metabolic Diseases
Harbin Medical University
2011-2022
First Affiliated Hospital of Harbin Medical University
2011-2022
Osteoarthritis (OA) is a multifactorial disease that associated with inflammation in joints. The purpose of the present study was to investigate anti-inflammatory activity and mechanism morin on human osteoarthritis chondrocytes stimulated by IL-1β.The levels NO PGE2 were measured Griess method ELISA. MMP1, MMP3, MMP13 also ELISA.The results revealed IL-1β significantly increased production NO, PGE2, MMP13. Additionally, increases attenuated treatment morin. Furthermore, IL-1β-induced NF-κB...
Growth differentiation factor (GDF)‑5 serves a role in tissue development and tenomodulin an important the of tendons. The effects GDF‑5 on mesenchymal stem cells (MSCs), particularly with regards to tendon bioengineering, are poorly understood. present study aimed investigate cell viability expression MSCs from murine compact bone. were isolated bones confirmed by flow cytometric analysis. In addition, adipogenic, osteoblastic chondrocyte capabilities determined. treated MSC mRNA protein...
To construct a ultraviolet-cross-linkable chitosan-carbon dots-morin (NMCM) hydrogel, observe whether it can repair cartilage injury by in vivo and vitro experiments, explore the related mechanism.The chitosan was taken to prepare ultraviolet (UV)-cross-linkable combining methacrylic anhydride, carbon dots acrylamide. The two solutions were mixed added morin solution. After UV irradiation, NMCM hydrogel obtained, its sustained release performance tested. Chondrocytes separated from normal...
The importance of cultivating evidence-based consciousness thinking and implementation capability specialization postgraduates was analyzed,and experiences suggestions acquired from the practice teaching were shared by demonstrating enlightening thinking,the cultivation establishment evaluation system,with PBL integrated. Key words: Clinical specialization; Postgraduates; Evidence-based consciousness; Evidence-based capability; Problem-based learning
Abstract Background: Osteosarcoma (OS) is a rare malignant primary tumor of mesenchymal origin affecting bone that occurs in adolescents and children. LncRNAs are important regulators tumorigenesis development. This study aimed to explore the role molecular basis LncRNA BACE1-AS OS. Methods results : Through analysis differential expressed lncRNAs OS tissues by GEO database, displayed remarkably lower expression. found could also be observed both cell lines qRT-PCR. Furthermore, using Cell...