A5101508406- Bone Tissue Engineering Materials
- Advanced Sensor and Energy Harvesting Materials
- biodegradable polymer synthesis and properties
- Hydrogels: synthesis, properties, applications
- Dental Implant Techniques and Outcomes
- Conducting polymers and applications
- Electrospun Nanofibers in Biomedical Applications
- Polymer Surface Interaction Studies
- Tissue Engineering and Regenerative Medicine
- Advanced Materials and Mechanics
- Supercapacitor Materials and Fabrication
- Bone Metabolism and Diseases
- Nanoparticle-Based Drug Delivery
- Silk-based biomaterials and applications
- Muscle Physiology and Disorders
- Advanced Drug Delivery Systems
- Bone and Dental Protein Studies
- Thermodynamic and Exergetic Analyses of Power and Cooling Systems
- Nerve injury and regeneration
- Graphene and Nanomaterials Applications
- interferon and immune responses
- Advanced Thermodynamic Systems and Engines
- Surgical Sutures and Adhesives
- RNA modifications and cancer
- Polymer Science and PVC
Ningxia Normal University
2020-2024
Beijing University of Chemical Technology
2018-2024
Huazhong Agricultural University
2024
First Affiliated Hospital of Chengdu Medical College
2000-2022
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
2021
A.E. Favorsky Irkutsk Institute of Chemistry
2021
Shanghai Institute of Technical Physics
2020
University of Shanghai for Science and Technology
2020
Chinese Academy of Sciences
2018-2020
Anhui Provincial Hospital
2020
Localized cancer treatments with combination drugs have recently emerged as crucial approaches for effective inhibition of tumor growth and reoccurrence. In this study, we present a new strategy the osteosarcoma treatment by localized co-delivery multiple drugs, including doxorubicin (DOX), cisplatin (CDDP) methotraxate (MTX), using thermosensitive PLGA-PEG-PLGA hydrogels. The release profiles from hydrogels were investigated in vitro. It was found that multidrug coloaded exhibited...
The next-generation portable and wearable energy-storage devices are expected to withstand distinguished mechanical strain damage. Hence, the electrolytes with superior self-healability, outstanding stretchability, excellent electrochemical performance necessary requirements for achieving advanced supercapacitors, but it still remains a huge challenge develop electrolytes. Herein, novel type of multifunctional supramolecular hydrogel electrolyte (3-dimethyl (methacryloyloxyethyl)ammonium...
Multifunctional conductive hydrogels attract booming attention with the prosperity of flexible and wearable soft devices such as energy storage systems sensors. However, conventional water-based inevitably lose ionic conductivity mechanical flexibility at subzero temperature, thus restricting their practical utilizations in extremely cold environments. On other hand, simultaneous realization high freezing tolerance, toughness, conductivity, electrochemical property through a simple approach...
Chitosan is a good biodegradable natural polymer, widely used in biomedical fields. In this study, chitosan was to modify the surface of poly (D,L-lactic acid) (PDLLA) order enhance its cell affinity. The properties modified PDLLA and control were investigated by contact angle electron spectroscopy for chemical analysis (ESCA), which indicated changes energy structure. Scanning microscopy (SEM) observation displayed differences morphology between chitosan-modified film control. These data...
Combination therapy is a promising and prevalent strategy for osteosarcoma treatment. Curcumin (CUR), as chemosensitizer, improves the antitumor effect of first‑line chemotherapy drugs. However, due to its poor solubility instability in physiological conditions, bioavailability CUR limited. In order improve physicochemical properties natural CUR, β‑cyclodextrin was adopted generate curcumin (CD‑CUR) inclusion complex. A thermosensitive hydrogel,...
For enhanced oral insulin delivery, a strategy of acid-resistant and enteric hydrogels encapsulating insulin-loaded nanoparticles was developed. The were prepared by the formation an anionic insulin/heparin sodium (Ins/HS) aggregate, followed coating chitosan (CS) on surface. nanoparticles, tagged as CS/Ins/HS NPs, exhibited excellent mucosa affinity, effective protease inhibition, marked paracellular permeation enhancement. Moreover, to improve acid-stability NPs impart capacity...
Gel polymers are widely used in different fields due to their unique properties, especially flexible electronic devices. However, developing multienvironmentally-tolerant (antifreezing, antidrying, and solvent-resistant) gel polymer-based soft electronics is still a significant challenge. Herein, binary solvent system-based versatile organohydrogel designed successfully prepared, which exhibits superior stretchability, favorable self-adhesive prominent temperature tolerance, excellent...
Abstract One of the challenges in field tissue engineering is development biomaterial/cell interactions. For purposes present study, two molecular weights poly(aspartic acid) (PASP) were used to modify poly( D,L ‐lactic (PDLLA) films order enhance their cell affinity. The properties PDLLA‐modified surfaces and controls investigated by water contact angle measurement electron spectroscopy for chemical analysis (ESCA). These data reflect change biocompatibility modified PDLLA surfaces. Then...
In order to explore the methods for commercialized bone tissue engineering, engineered bones should be cultivated in bioreactors realize three‐dimensional culture under well‐defined conditions. present paper, osteoblasts isolated from cranium of 1‐month‐old Zelanian rabbits were inoculated on BDBS (bio‐derived scaffolds) investigate fabrication an RWVB (rotating‐wall vessel bioreactor). The osteoblasts, after being transfected with green fluorescent protein, respectively seeded at 2×10 6 and...
Polyvinyl alcohol (PVA) with abundant hydroxyl groups (−OH) has been widely used for membranes, hydrogels, and films, its function is largely affected by the alcoholysis degree. Therefore, development of rapid accurate methods degree determination in PVAs important. In this contribution, we have proposed a novel fluorescence-based platform probing PVA using (E)-N-(4-methoxyphenyl)-1-(quinolin-2-yl)methanimine (QPM)-Zn2+ complex as reporter. The mechanism study disclosed that strong...
Hydrogels with integrated attributes of mechanical toughness, transparency, self-healing ability, and freezing tolerance have attracted tremendous attention because their promising applications in advanced intelligent systems, flexible energy storage devices, wearable electronics. Herein, we developed a multifunctional gel polymer hybrid double network structures by introducing the biological macromolecular chains gelatin chemically cross-linked DMA (N,N-dimethylacrylamide)-AA (acrylic acid)...
The
Hsa_circ_0000285, a novel circular RNA, has been proven to extensively take part in the pathogenesis of numerous tumors. In hepatocellular carcinoma (HCC), very little is known about hsa_circ_0000285 until now. Hence, this research aims determine hsa_circ_0000285's functional role and underlying mechanisms HCC.The expressions miR-582-3p, hsa_circ_000028, cyclin B2 (CCNB2) among HCC cells tumor samples were determined by performing western blotting qRT-PCR analyses. The impacts...
Poly(D,L-lactic acid) (PDLLA) was modified with alkylated chitosan (N-butyl and N-cetyl chitosan), the effects of films on functions rat osteoblasts were investigated. The characteristics surfaces(both control) examined by water contact angle measurement electron spectroscopy for chemical analysis (ESCA). Cell morphologies these surfaces taken using scanning microscopy (SEM). attachment proliferation used to assess cell behavior surface control. MTT assay determined viability, alkaline...
Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI