A5049785145- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Mechanical Circulatory Support Devices
- Aortic aneurysm repair treatments
- Cardiac and Coronary Surgery Techniques
- Congenital Heart Disease Studies
- Heart Failure Treatment and Management
- Infectious Aortic and Vascular Conditions
- Acute Myocardial Infarction Research
- Peripheral Artery Disease Management
- Bacterial Infections and Vaccines
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac tumors and thrombi
- Orthopedic Infections and Treatments
- Autophagy in Disease and Therapy
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- Case Reports on Hematomas
- Renal and Vascular Pathologies
- Tissue Engineering and Regenerative Medicine
- Cardiac Arrest and Resuscitation
IRCCS Humanitas Research Hospital
2022-2024
Humanitas University
2018-2021
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2021
Sapienza University of Rome
2015-2019
Intraluminal aortic clamping has been achieved until now by means of a sophisticated device consisting three-lumen catheter named Endoclamp, which allows at the same time occlusion aorta, antegrade delivering cardioplegia, and venting through root. This tool shown important advantages allowing perfusate without direct contact with ascending aorta reducing meanwhile risk traumatic and/or iatrogenic injuries. Recently, new (Intraclude catheter) characteristics properties proposed introduced in...
Thoracic aortic aneurysms (TAA) pathogenesis and progression include many mechanisms. The authors investigated the role of autophagy, oxidative stress, endothelial dysfunction in 36 TAA patients 23 control patients. Univariable multivariable analyses were performed. displayed higher stress then Autophagy group was reduced. association autophagy with disease supports these processes TAA. demonstrate a putative Nox2 dysregulation human These findings could pinpoint novel treatment targets to...
This study evaluates the long-term outcomes of minimally invasive mitral valve repair (MIMVR) in patients with degenerative regurgitation, focusing on survival, failure, and re-operation rates. A cohort undergoing three primary techniques-quadrangular resection, edge-to-edge repair, artificial chordae implantation-was analyzed using time-to-event methods. The overall survival rates at 1, 10, 20 years were high comparable among techniques, indicating effective benefits MIMVR. However, freedom...
Abstract Bicuspid aortic valve (BAV) disease is recognized to be a syndrome with complex and multifaceted pathophysiology. Its progression modulated by diverse evolutionary conserved pathways, such as Notch-1 pathway. Emerging evidence also highlighting the key role of TLR4 signaling pathway in pathologies their related complications, sporadic ascending aorta aneurysms (AAA). Consistent these observations, we aimed evaluate both BAV its common complication, AAA. To this aim, 70 subjects (M/F...
Abstract OBJECTIVES Reports ranged from mixed to marginal tubing wear and spallation effects as a complication of roller pumps in cardiopulmonary bypass (CPB). Because the rollers constantly compress part tubing, we sought determine whether circuit materials behave differently under 3-h simulation CPB. METHODS Two different (silicone Tygon) were tested with customized experimental circuit, designed allow vitro CPB priming volumes, pressures, revolutions per minute temperatures equivalent...
Congenital fibromuscular bands have been described in left ventricle or right atrium and diagnosed by echocardiography CT scan. The first report of anomalous band the was 1897 Rollestone (1). We hereby present a case patient with an incidental finding atrial during minimally invasive mitral surgery procedure.
Abstract Ventricular assist devices (VADs) are considered the standard of care for end‐stage heart failure (HF) patients. Despite increasing confidence in technology, evidence data, endorsement by scientific societies and guidelines, number implants reached a steady state is not at expected pace. This most likely related to complications that still burdening technology consequently excluding needy, ill, fragile population. In this manuscript we reporting single‐center experience very...
Clinical pathway of an intracardiac hematoma treated by ECMO support.
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral or pulmonary etc.
Background and Aim of the Study: Barlow’s disease is characterized by excess myxomatous degenerative tissue, leaflets prolapse and/or billowing, chordal-elongation, annular-dilation. We reviewed our experience in Minimally Invasive Mitral Valve Repair (MIMVR) techniques to treat this complex mitral pathology. Methods: Between 1999 2017 a group 125 patients was identified as undergoing MIMVR. The diagnosis Barlow based upon preoperative transesophageal-echocardiography (TEE) confirmed...
Abstract Background Recent evidence has rendered percutaneous coronary intervention (PCI) a valuable alternative to artery bypass grafting (CABG) in patients with left main disease (LMCAD). Nevertheless, the optimal management and selection is still subject discussion Methods We retrospectively included 431 treated PCI 324 CABG primary objective of comparing procedural failure according revascularization strategy. Secondary endpoints were post clinically relevant myocardial infarction,...