A5050767535- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Reproductive Biology and Fertility
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Sperm and Testicular Function
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Cardiac Ischemia and Reperfusion
- Ovarian function and disorders
- Connective tissue disorders research
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Pulmonary Hypertension Research and Treatments
- Infectious Aortic and Vascular Conditions
- Reproductive Health and Technologies
- Cardiac tumors and thrombi
- Anesthesia and Neurotoxicity Research
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Coronary Artery Anomalies
- Pericarditis and Cardiac Tamponade
University of Rome Tor Vergata
2015-2024
Policlinico Tor Vergata
2015-2024
Centro Medicina della Riproduzione
2010-2023
Saint Camillus International University of Health and Medical Sciences
2019
Vanda Institute
2019
Society of Thoracic Surgeons
2018
Terra
2005-2017
Northern General Hospital
2017
San Diego Cardiac Center
2016-2017
University of Palermo
2007-2016
Bicuspid valve disease is associated with the development of thoracic aortic aneurysm. The molecular mechanisms underlying this association still need to be clarified. Here, we evaluated circulating levels T and B lymphocyte subsets vascular diseases in patients bicuspid or tricuspid without We unveiled that MAIT, CD4+IL−17A+, NKT cell were significantly reduced cases, when compared cases either presence absence Among valve, these cells higher those also affected by Similar data obtained...
Thoracic aortic aneurysm (TAA) is a progressive disorder involving gradual dilation of ascending and/or descending thoracic aorta with dissection or rupture as complications. It occurs sporadic defined syndromes/familial forms.Genetic, molecular and cellular mechanims TAA forms are poorly characterized known. Thus, our interest has been focused on investigating the role genetic variants transforming growth factor-β (TGF-β) pathways in risk. On other hand, no data TGF-β pathway exist until...
A prospective study was performed to assess the relationship between human papillomavirus (HPV) infection in 199 infertile couples and outcome of assisted reproductive technologies (ARTs). highly statistically significant correlation pregnancy loss rate (proportion pregnancies detected by β-hCG that did not progress beyond 20 weeks) positive HPV DNA testing male partner couples, compared with negatives, observed (66.7% vs. 15%).
Pulmonary hypertension increases morbidity and mortality in patients undergoing heart surgery. Mitral valve stenosis is frequently associated with an increase pulmonary vascular resistance (PVR). Cardiopulmonary bypass exacerbates cardiac The aim of this study was to compare the hemodynamic effects inhaled prostacyclin nitric oxide administration i.v. nitroprusside during surgery a clinical, pharmacodynamic dose-response, prospective, randomized, double-blind (Group A: prostacyclin; Group B:...
Abstract OBJECTIVES In the last decades, 4 different scores for prediction of mortality following surgery type A acute aortic dissection (TAAD) were proposed. We aimed to validate these in a large external multicentre cohort. METHODS retrospectively analysed patients who underwent TAAD between 2000 and 2020. Patients enrolled from 10 centres 2 European countries. Outcomes early (30-day and/or in-hospital) 1-year mortality. Discrimination, calibration observed/expected (O/E) ratio evaluated....
The involvement of different factors in the onset thoracic aortic aneurysm (TAA) patients with a bicuspid valve (BAV) vs those tricuspid (TAV) is well recognized. However, molecular, genetic and cellular mechanisms driving TAA remain unclear. aim this study was to identify involved development BAV TAV.Aorta specimens DNA samples were collected from 24 (18 men 6 women; mean age: 54.2 ± 14.39 years) 110 TAV (79 31 women, 66 9.8 patients. A control group 128 subjects (61 67 woman, 61.1 5.8 also...
STUDY QUESTIONWhat is the effect of FSHB-211G>T together with FSHR 2039 A>G on serum FSH in women?
Bicuspid aortic valve (BAV) is frequently associated with the development of ascending aneurysm, even if underlying mechanisms remain to be clarified. Here, we investigated a deregulation Notch1 signaling pathway and endothelial progenitor cells (EPCs) number BAV disease an early aneurysm (AAA) onset. For this purpose, 70 subjects (M/F 50/20; mean age: 58.8 ± 14.8 years) tricuspid (TAV) 35/35; 69.1 12.8 AAA complicated or not, were included. Interestingly, patients showed significant...
We retrospectively evaluated early and intermediate outcomes of aortic arch surgery in patients with type A acute dissection (AAD), investigating the effect extension on postoperative results. From January 2006 through July 2013, 201 AAD underwent urgent corrective at our institution. Of 92 chosen for this study, 59 hemiarch replacement (hemiarch group), 33 total (total group) conjunction ascending aorta replacement. The operative mortality rate was 22%. Total associated a 33% risk death,...
Abstract Background We have evaluated in a single-center retrospective study early and mid-term outcomes of intermittent warm blood St. Thomas cold crystalloid cardioplegia patients referred for coronary artery bypass grafting (CABG) due to acute syndromes (ACS). From January 2018 December 2023, 336 consecutive underwent isolated on-pump CABG (unstable angina = 234, 69.6%; N-STE-myocardial infarction 66, 19.6%; STE-myocardial 36, 10.7%). Myocardial protection was achieved using (WBC, n 215,...