Khalil Fattouch

ORCID: 0000-0002-6556-9519
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Structural Anomalies and Repair
  • Aortic Disease and Treatment Approaches
  • Cardiac and Coronary Surgery Techniques
  • Cardiac Imaging and Diagnostics
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Arrhythmias and Treatments
  • Coronary Interventions and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Congenital Heart Disease Studies
  • Cardiac pacing and defibrillation studies
  • Aortic aneurysm repair treatments
  • Atrial Fibrillation Management and Outcomes
  • Mechanical Circulatory Support Devices
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Ischemia and Reperfusion
  • Pericarditis and Cardiac Tamponade
  • COVID-19 Clinical Research Studies
  • Coronary Artery Anomalies
  • Cardiac Arrest and Resuscitation
  • Cardiovascular Effects of Exercise
  • Cardiovascular Issues in Pregnancy
  • Peptidase Inhibition and Analysis
  • Acute Kidney Injury Research

Maria Eleonora Hospital
2016-2025

Università degli Studi di Enna Kore
2024-2025

University of Palermo
2013-2024

Regione Siciliana
2015-2024

All India Institute of Medical Sciences
2024

Ospedale San Carlo
2023

Maria Cecilia Hospital
2011-2022

Villa Maria Hospital
2022

Woodlands Hospital
2020

Lille’s Cardiology Hospital
2018

The natural history and the management of patients with asymptomatic aortic stenosis (AS) have not been fully examined in current era.To determine clinical outcomes AS using data from Heart Valve Clinic International Database.This registry was assembled by merging prospectively gathered institutional databases 10 heart valve clinics Europe, Canada, United States. Asymptomatic an area 1.5 cm2 or less preserved left ventricular ejection fraction (LVEF) greater than 50% at entry were considered...

10.1001/jamacardio.2018.3152 article EN JAMA Cardiology 2018-10-03

Pulmonary hypertension increases morbidity and mortality in patients undergoing heart surgery. Mitral valve stenosis is frequently associated with an increase pulmonary vascular resistance (PVR). Cardiopulmonary bypass exacerbates cardiac The aim of this study was to compare the hemodynamic effects inhaled prostacyclin nitric oxide administration i.v. nitroprusside during surgery a clinical, pharmacodynamic dose-response, prospective, randomized, double-blind (Group A: prostacyclin; Group B:...

10.1111/j.0886-0440.2005.200383w.x article EN Journal of Cardiac Surgery 2005-02-22

Tricuspid regurgitation (TR) is a frequent and complex problem, commonly combined with left-sided heart disease, such as mitral regurgitation. Significant TR associated increased mortality if left untreated or recurrent after therapy. was historically often disregarded remained undertreated. Surgery currently the only Class I Guideline recommended therapy for TR, in form of annuloplasty, leaflet repair, valve replacement. As growing experience transcatheter structural many dedicated...

10.1093/eurheartj/ehz614 article EN European Heart Journal 2019-08-09

Numerous speculations have been made in recent years about the future of cardiac surgery, seen by some as an "obsolete" discipline and reserved for complex/emerging cases. From central database private-affiliated group GVM Care & Research with National Health System, data from 2014 to 2023 relating elective surgery (57 736 patients) were extracted 12 centers located throughout country, specific reference isolated coronary valvular surgery. The number interventions performed has progressively...

10.1714/4464.44615 article EN PubMed 2025-04-01

Objective Pulmonary hypertension can already be present in patients undergoing cardiac surgery or exacerbated by cardiopulmonary bypass. Postoperative treatment is still a challenge for physicians. The aim of this study was to evaluate the effects inhaled prostacyclin (iPGI2) and nitric oxide (iNO) compared with those intravenous vasodilators. Methods This prospective, randomized, double-blind included 58 affected severe mitral valve stenosis pulmonary high vascular resistance (> 250...

10.2459/01.jcm.0000203850.97890.fe article EN Journal of Cardiovascular Medicine 2006-02-01

Background: The inflammatory cascade has been hypothesized to be an important mechanism of post-ischaemic myocardial reperfusion injury and several studies demonstrated that C1 esterase inhibitor (C1-INH) is effective in post-ischaemia protection. Therefore, we aimed investigate prospectively a randomised double-blind study the cardioprotective effects C1-INH ST segment elevation infarction (STEMI) patients who underwent emergent with coronary artery bypass grafting (CABG). Methods: In this...

10.1016/j.ejcts.2007.04.038 article EN European Journal of Cardio-Thoracic Surgery 2007-06-19

Aortic stenosis (AS) is a common valvular heart disease in the Western populations, with an estimated overall prevalence of 3% adults over 75 years. To understand its patho-biological processes represents priority. In elderly patients, AS usually involves trileaflet valves and referred to as degenerative calcific processes. Scientific evidence suggests involvement active "atherosclerosis-like" pathogenesis initiation phase AS. contrary, progression could be driven by different forces (such...

10.11909/j.issn.1671-5411.2016.06.001 article EN PubMed 2016-09-01

Surgical aortic valve replacement (AVR) can be performed via a full sternotomy or minimal access approach (mini-AVR). Despite long-term experience with the procedure, mini-AVR is not routinely adopted. Our goal was to compare contemporary outcomes of and conventional AVR in large multi-institutional national cohort.A total 5801 patients from 10 different centres who had (2851) (2950) 2011 2017 were evaluated retrospectively. Standard prostheses used all cases. The use minimally invasive has...

10.1093/ejcts/ezz286 article EN European Journal of Cardio-Thoracic Surgery 2019-10-02
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