A5089319431- Vestibular and auditory disorders
- Systemic Sclerosis and Related Diseases
- Systemic Lupus Erythematosus Research
- Olfactory and Sensory Function Studies
- Head and Neck Surgical Oncology
- Mast cells and histamine
- Tuberculosis Research and Epidemiology
- Glaucoma and retinal disorders
- Toxin Mechanisms and Immunotoxins
- Urticaria and Related Conditions
- Hearing, Cochlea, Tinnitus, Genetics
- Hearing Loss and Rehabilitation
- Mycobacterium research and diagnosis
- Sinusitis and nasal conditions
- Metastasis and carcinoma case studies
- Ocular Surface and Contact Lens
- Sarcoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Amoebic Infections and Treatments
- Cancer Treatment and Pharmacology
- Glioma Diagnosis and Treatment
- Climate variability and models
Gunma University Hospital
2009-2025
Tokushima University
2019-2024
Institute of Biomedical Science
2023-2024
Japan Meteorological Agency
2019-2023
National Hospital Organization Kochi National Hospital
2023
Kurume University
2021-2022
Tokushima University Hospital
2022
Tokushima Breast Care Clinic
2020
Tokyo University of Science
2019
Hokkaido University
2016
Abstract RNA viruses use various strategies to condense their genetic information into small genomes. Potyviruses not only the polyprotein strategy, but also embed an open reading frame, pipo , in P3 cistron –1 frame. PIPO is expressed as a fusion protein with N-terminal half of (P3N-PIPO) via transcriptional slippage viral RNA-dependent polymerase (RdRp). We herein show that clover yellow vein virus (ClYVV) produces previously unidentified factor, P3N-ALT, +1 frame at conserved G 1–2 A 6–7...
Adverse reactions to iodinated and gadolinium contrast media are an important clinical issue. Although some guidelines have proposed oral steroid premedication protocols prevent adverse reactions, patients may in spite of (breakthrough reaction; BTR). The purpose this study was assess the frequency, type severity BTR when following protocol. All contrast-enhanced radiologic examinations between August 2011 February 2013 for which protocol applied our institution were assessed BTRs. a total...
Two cases of hypertensive pulmonary vascular disease with Raynaud's phenomenon are reported. One is a 32-year-old housewife primary hypertension some immunological disorders and the other 28-year-old female systemic lupus erythematosus. It may be considered that process could play role in etiology relationship pathogenesis between these 2 was discussed.
The effects of FM system fitted into the normal hearing ear (NHE) or a cartilage conduction aid (CCHA) affected (AE) on speech recognition ability in noise were examined children with unilateral congenital aural atresia (UCAA). In bilateral (BNH), score (SRS) was significantly decreased noisy environment -5 dB signal-to-noise ratio (SNR), compared those quiet. UCAA, SRS environments 0 and SNR, UCAA decreased, BNH. aided by NHE better than unaided same group. CCHA AE tended to be higher can...
In this paper the characteristics of vascular system rabbit popliteal lymph nodes, especially function post-capillary venules was investigated. The presence direct passage from flow to blood within nodes proved on various substances macromolecules. results are as follows:1. most characteristic feature microcirculatory architecture is venule which named after Schulze.2. form complicated venous plexuses in cortical lymphatic matrix.3. does not appear embryonic stage and able be observed second...
Three cases of pancreatoblastoma in children were examined immunohis‐tochemically and the results compared with those pancreatic duct carcinoma adults. The demonstrated positive reactions to α‐fetoprotein (AFP) (67%: 2/3), α‐1‐antitrypsin (AAT) (100%: 3/3), carcinoembryonic antigen (CEA) (67% : 2/3) keratin (33% 1/3), although CEA was only weakly both cases. On other hand, adult showed as follows; AFP: 3% (1/29), AAT: 21% (6/29), CEA: 97% (28/29) keratin: 93% (27/29). Also, endocrine...
Background: Vestibular compensation (VC) after unilateral labyrinthectomy (UL) consists of the initial and late processes. These processes can be evaluated based on decline in frequency spontaneous nystagmus (SN) number MK801-induced Fos-positive neurons contralateral medial vestibular nucleus (contra-MVe) rats. Histamine H3 receptors (H3R) are reported to involved development VC. Objective: We examined effects betahistine, an H3R antagonist, VC UL Methods: Betahistine dihydrochloride was...
Twenty-two patients with definite or classical rheumatoid arthritis (RA) who were diagnosed as amyloidosis by biopsy at autopsy investigated. The average duration of RA prior to the diagnosis was 16.5 +/- 12.5 years. symptoms that led renal in 11 cases and gastrointestinal 5 cases. Urinary protein positive 16 (73%). degree proteinuria varied each case. Nephrotic syndrome observed Azotemia (Cr greater than 1.5 mg/dl) present 18 (82%). period from death 3.0 2.2 causes uremia 10 cases, heart...
Background: Unilateral labyrinthectomy (UL) causes the disappearance of ipsilateral medial vestibular nuclear (ipsi-MVe) activity and induces spontaneous nystagmus (SN), which disappears during initial process compensation (VC). Ipsi-MVe-activity restores in late VC.Objective: We evaluated VC after UL rats examined effects thioperamide (H3 antagonist) on VC.Materials methods: MK801 (NMDA antagonist)-induced Fos-like immunoreactive (-LIR) neurons contra-MVe, had been suppressed by...
Globus pharyngeus (GP) is a common symptom of laryngopharyngeal reflux disease (LPRD), and proton pump inhibitor (PPI) rikkunshito, traditional Japanese medicine having prokinetic effect improve LPRD symptoms. In the present study, we examined efficacy high-dose PPI in combination with rikkunshito patients complaining GP.106 GP without any organic endoscopic findings were enrolled.Patients first administrated alone for 4 to 8 weeks was improved 65 patients. Among 41 PPI-refractory GP, 22 14...
Diazepam, a gamma-aminobutyric acid type A receptor agonist, is classified as vestibular suppressant and effective in treating acute vertigo. However, its effects on compensation (VC) remain unclear.We examined the of continuous administration diazepam frequency spontaneous nystagmus (SN) after unilateral labyrinthectomy (UL) an index initial process VC rats.Diazepam was continuously administered at doses 3.5 7.0 mg/kg/day, intraperitoneally, via osmotic minipump. The SN beating against...
The high spatial resolution and cost performance of functional magnetic resonance imaging (fMRI) is useful for estimating focus localization in epilepsy, but this difficult the case ictal fMRI because susceptible to motion artifacts. Electroencephalogram (EEG)-triggered fMRI, which interictal, can be performed without marked movement thought useful, requires further investigation order establish a methodology. authors studied EEG-triggered partial epileptic patients. Six patients were...
The effectiveness of multiple ensembles to determine 70% probability-circle radii operational tropical cyclone (TC) track forecasts in the Japan Meteorological Agency (JMA) is investigated. used this study are global from JMA, European Centre for Medium-Range Weather Forecasts (ECMWF), National Centers Environmental Prediction (NCEP) and Met Office United Kingdom (UKMO). verification all TCs 2016 2018 reveals that ensemble-based method has stronger correlation with TC forecast errors clearer...
We report the case of a 15-year-old young man who presented with disequilibrium and leftward spontaneous nystagmus. Since video head impulse test at initial visit showed right lateral semicircular canal hypofunction, patient was suspected as having peripheral vertigo due to hypofunction. However, his clinical course considered being atypical for caused by hypofunction because small center gravity sway, negative Romberg's phenomenon. Balance testing failure visual suppression caloric...