Abstract Flexible wearable sensors with bimodal functionality offer substantial value for human health monitoring, as relying on a single indicator is insufficient capturing comprehensive physiological information. However, face multiple challenges in practical applications, including mutual interference between various modalities, and integration of excellent mechanical properties, interfacial adhesion, environmental adaptability biocompatibility. Herein, the multifunctional hydrogel,...

Abstract Piezoelectric materials can produce electrical power from the mechanical stimulation and thus, they may accelerate electroactive tissue healing as a promising treatment for traumatic peripheral nerve injuries. In this study, piezoelectric zinc oxide nanogenerator scaffold is manufactured by 3D injectable multilayer biofabrication. The polymeric displays desirable physical characteristics, such aligned porosity, high elasticity, stiffness, surface energy, excellent shear behavior....

Abstract Background The need for radiotherapy among the elderly rises with increasing life expectancy and a corresponding increase of cancer patients. Radiation-induced skin injury is one most frequent adverse effects in patients, severely limiting their quality. Re-epithelialization collagen deposition have essential roles recovery injuries induced by high doses ionizing radiation. At same time, radiation-induced senescent cells accumulate irradiated tissues. However, mechanisms on...

Peripheral nerve injury is one common clinical disease worldwide, in which sciatic anatomically the most challenging to regenerate given its length and large cross-sectional area. For present, autologous grafting remains be ideal strategy when treating with injury. However, this method sacrifices healthy nerves requires highly intensive surgery, still calling for other advanced alternatives grafting.In study, we utilized previously well-established gene delivery system dually deliver plasmid...

Abstract Volumetric muscle loss (VML) caused by injury or trauma affects the quality of life directly, due to its high incidence, lingering healing, and prolonged duration. Tissue engineered scaffolds have been widely used in regeneration for patients with massive injury. Melatonin (MLT) is a bioactive substance secreted pineal gland, which can promote recovery inhibiting oxidative stress inflammation. Herein, biocompatible scaffold developed using thiolated hyaluronic acid (HA‐SH), collagen...

Few studies have analyzed the association of factors contributing to morphologic changes medial osteochondral lesions talus (OLTs). Two hundred eighty consecutive patients who underwent surgery for OLTs from January 2010 December 2022 were enrolled. The potential age, gender, side injury, duration symptoms, body mass index, history ankle sprain, chronic lateral instability (CLAI), and varus. Multivariate logistic regression analysis was performed evaluate between these both size Hepple...

Ankle distraction arthroplasty is one option for the treatment of severe ankle arthritis in young patients. The outcomes and factors predicting success are poorly understood.From January 2011 to May 2015, 16 patients who had undergone were operated, including six males ten females. All available analysis. main outcome measurements included joint space on weight bearing radiographs, AOFAS-AH scores (American Orthopaedic Foot & Society ankle-hindfoot score), VAS SF-36 scores.All followed a...

It is controversial whether supramalleolar osteotomy suitable for Takakura Stage 3B osteoarthritis or not. The aim of this study was to evaluate the outcomes in patients with osteoarthritis. From February 2008 August 2013, performed 21 matching inclusion criteria. mean patient age at operation 53.7±5.8 years (range: 39 61 years). duration follow-up 87.7±19.5 months 125 months). radiologic evaluation included tibial articular surface (TAS) angle, lateral (TLS) and talar tilt (TT) angle....

Osteochondral lesions of the talus (OLTs) are amongst most common foot and ankle disorders. Varus malalignment causes stress concentration on medial side joint, resulting in OLTs osteoarthritis. For large symptomatic (>10 mm), autograft transplantation is usually recommended. This article highlights biplanar distal tibial osteotomy as an approach management for patients with concomitant varus malalignment. From January 2012 to July 2014, 13 (6 male 7 female) underwent surgery our faculty...

The timing and strategy for operative treatment of flatfoot are still controversial. purpose this study was to evaluate clinical outcomes radiographic changes following calcaneal Z osteotomy combined with subtalar arthroereisis severe adolescent flexible flatfoot.Data were analyzed 16 patients (20 feet) who had without tibialis posterior tendon dysfunction treated by between October 2011 February 2015. mean age at the time surgery 12.8 ± 1.4 years (range, 10-14 years). Preoperative...

Acute respiratory distress syndrome (ARDS) leads to the acute lung injury (ALI), a form of diffused alveolars injury, accompanied by severe inflammation and oxidative damage alveolar epithelial cells. α-Tocopherol (α-TOH), one eight isoforms vitamin E, is natural antioxidant-free radical. We aimed understand effect α-TOH mechanism involved in inducing ALI. Lipopolysaccharide (LPS) injected into trachea mice generate ALI mouse models. was used administrate intragastrically detect expression...

To investigate the short and medium term outcomes of bone defect reconstruction with cement prosthesis after clavicle malignancies resection. A total 5 clavicular malignancy patients experienced subtotal claviculectomy were enrolled study from January 2005 to May 2012. Musculoskeletal Tumor Society score (MSTS), Visual Analogue scale (VAS) American Shoulder Elbow Surgeons shoulder outcome (ASES) adopted for assessment. The mean follow-up period was 25.8 months. All performed claviculectomy....

Objective To evaluate the impact of an enhanced recovery after surgery (ERAS) pathway on patients undergoing minimally invasive radical prostatectomy at a single institute. Methods In this retrospective study, 301 who underwent laparoscopic or robot-assisted from May 2014 to September 2018 were consecutively recruited. Before April 2017, treated with conventional care; all ERAS thereafter. The primary outcome was postoperative length hospital stay (LOS). secondary outcomes hospitalization...

Diffused-type giant cell tumor(Dt-GCT) is a rare, aggressive disorder of the joint synovium, bursa and tendon sheaths. Osseous erosions subchondral cysts may develop as result synovium infiltration in Dt-GCT. We present retrospective study series patients who are diagnosed with Dt-GCT about ankle joint, there clinical outcome evaluated this study.Fifteen radiologically histologically confirmed were identified our foot department. Patients managed open synovectomy for tumor tissue bone...

Several minimally invasive anatomic reconstruction techniques of the lateral ligaments have been introduced for treatment chronic ankle instability. However, these strategies may not always follow accurate ligament attachments, especially in construction fibular bone tunnels. This study reported a new percutaneous technique anatomically with Tightrope system. From April 2016 to August 2016, 25 ankles 24 patients instability underwent our The operation was performed through several small...

To describe the technique and analyze outcomes of joint-preserving surgical treatments which included anatomical reconstruction or alignment correction for talar malunions nonunions, avoid development degenerative changes in adjacent joints.Eight patients who had painful nonunions treated between 2009 2015 were this retrospective study. The mean age was 35.6 years, with aged from 18 to 58 years. Two neck fractures six body fractures. According a classification post-traumatic deformities,...

The timing and strategy of treatment for flatfoot still remain controversial. It is a difficult problem when facing severe adolescent flexible because single procedure cannot realign deformity effectively.We reviewed 13 patients who underwent double calcaneal osteotomy during May 2012 to June 2015. mean age was 15.2 ± 1.8 (range, 10-18) years. American Orthopaedic Foot Ankle Society Ankle-Hindfoot (AOFAS-AH) scores SF-36 score were adopted evaluate the preoperative postoperative functions...