A5080888429- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Traumatic Brain Injury Research
- Neuroscience and Neuropharmacology Research
- Cannabis and Cannabinoid Research
- Image and Signal Denoising Methods
- Neurotransmitter Receptor Influence on Behavior
- Memory and Neural Mechanisms
- Neurobiology of Language and Bilingualism
- Medical Image Segmentation Techniques
- Bacteriophages and microbial interactions
- Topological and Geometric Data Analysis
- Advanced Sensor and Control Systems
- NMR spectroscopy and applications
- Neural dynamics and brain function
- Cognitive Abilities and Testing
- Fire dynamics and safety research
- Viral gastroenteritis research and epidemiology
- Atomic and Subatomic Physics Research
- Logic, programming, and type systems
- Tracheal and airway disorders
- Attachment and Relationship Dynamics
- Plant Virus Research Studies
Indiana University Bloomington
2016-2025
China-Japan Friendship Hospital
2024
Capital Medical University
2024
Indiana University
1997-2024
Eugene O'Neill Theater Center
2020-2021
Indiana University – Purdue University Indianapolis
2021
China Construction Bank
2008
TiVo (United States)
2005
American College of Surgeons
1997
University of Minnesota
1997
This article demonstrates the encapsulation of cubic iron oxide nanoparticles (NPs) by Brome mosaic virus capsid shells and formation, for first time, virus-based (VNPs) with cores. Cubic NPs functionalized phospholipids containing poly(ethylene glycol) tails terminal carboxyl groups exhibited exceptional relaxivity in magnetic resonance imaging experiments, which opens way vivo MRI studies systemic movement plants. Preliminary data on cell-to-cell long-distance transit behavior VNPs...
Recent studies of schizophrenia have revealed cognitive and memory deficits that are accompanied by disruptions neuronal connectivity in cortical subcortical brain regions. More recently, alterations topological organization structural networks also being identified using graph theoretical analysis. However, the role cerebellum this network structure remains largely unknown. In study, global measures obtained from diffusion tensor imaging were computed cerebella 25 patients with 36 healthy...
Importance Recurring exposure to head impacts in American football has garnered public and scientific attention, yet neurobiological associations adolescent players remain unclear. Objective To examine cortical structure neurophysiological characteristics players. Design, Setting, Participants This cohort study included control athletes (swimming, cross country, tennis) from 5 high school athletic programs, who were matched with age, sex (male), school. Neuroimaging assessments conducted May...
Chronic cannabis use can cause cognitive, perceptual and personality alterations, which are believed to be associated with regional brain changes possible in connectivity between functional regions. This study aims identify the from resting state magnetic resonance imaging scans. A two-level multi-voxel pattern analysis was proposed classify male users normal controls. The first level works on a voxel basis identifies clusters for input of second analysis, these We found distinct middle...
Morphological brain changes as a consequence of new learning have been widely established. Learning second language (L2) is one such experience that can lead to rapid structural neural changes. However, still relatively little known about how levels proficiency in the L2 and age at which learned influence neuroplasticity. The goal this study provide novel evidence for effect bilingualism on white matter structure proficient but late learners who acquired after early childhood. Overall,...
Complex visual-motor behaviors dominate human-environment interactions. Letter production, writing individual letters by hand, is an example of a complex behavior composed numerous behavioral components, including the required motor movements and percepts that those create. By manipulating isolating components letter we provide experimental evidence this supported widespread neural system smaller subsystems related to different sensorimotor components. Adult participants hand-printed with...
Abstract Cellular studies indicate that endocannabinoid type‐1 retrograde signaling plays a major role in synaptic plasticity. Disruption of these processes by delta‐9‐tetrahydrocannabinol (THC) could produce alterations either structural and functional brain connectivity or their association cannabis (CB) users. Graph theoretic networks were generated with diffusion tensor imaging resting‐state 37 current CB users 31 healthy non‐users. The primary outcome measures coupling between...
Endocannabinoid receptors modulate synaptic plasticity in the brain and may therefore impact cortical connectivity not only during development but also response to substance abuse later life. Such alterations be evident volumetric measures utilized imaging, could affect local global organization of networks. To test this hypothesis, we used a novel computational approach estimate network structural derived from diffusion tensor imaging (DTI) white matter tractography. Twelve adult cannabis...
Here, for the first time, we demonstrate formation of virus-like nanoparticles (VNPs) utilizing gold-coated iron oxide as cores and capsid protein brome mosaic virus (BMV) or hepatitis B (HBV) shells. Further, cryo-electron microscopy single particle methods, are able to show that BMV coat on VNPs assembles into a structure very close native virion. This is consequence an optimal NP size (∼11 nm) fitting cavity ultrathin gold layer maghemite cores, which allows utilization...
Background Magnetic resonance imaging (MRI) studies have shown differences in volume and structure the brains of individuals with alcohol use disorder (AUD). Most research has focused on neuropathological effects that appear after years chronic misuse. However, few investigated white matter (WM) microstructure diffusion MRI–based (DWI) connectivity during early stages AUD. Therefore, goal this work was to investigate WM integrity structural emerging adulthood AUD subjects using both...
Growing evidence suggests that glutamate neurotransmission plays a critical role in alcohol addiction. Cue-induced change of has been observed animal studies but never investigated humans. This work investigates cue-induced forebrain individuals with use disorder (AUD). A total 35 subjects (17 AUD and 18 healthy controls) participated this study. The concentration was measured single-voxel 1H-MR spectroscopy at the dorsal anterior cingulate. Two MRS sessions were performed succession, first...
Though sub-concussive impacts are common during contact sports, there is little consensus whether repeat blows affect brain function. Using a "lifetime exposure" rather than acute exposure approach, we examined oculomotor performance and activation among collegiate football players two control groups. Our analysis group differences in eye movement behavioral smooth pursuit. Data from 21 off-season Division I "starters" were compared with a) 19 cross-country runners, b) 11 non-athlete college...