A5089283179- Fermentation and Sensory Analysis
- Plant biochemistry and biosynthesis
- Fungal and yeast genetics research
- Photosynthetic Processes and Mechanisms
- Immunotherapy and Immune Responses
- Protein Degradation and Inhibitors
- Multiple Myeloma Research and Treatments
- Antioxidant Activity and Oxidative Stress
- Listeria monocytogenes in Food Safety
- Toxin Mechanisms and Immunotoxins
- Salmonella and Campylobacter epidemiology
- Amino Acid Enzymes and Metabolism
- Biochemical and Structural Characterization
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Microbial Metabolic Engineering and Bioproduction
- Phytochemicals and Antioxidant Activities
- Biochemical Analysis and Sensing Techniques
- vaccines and immunoinformatics approaches
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Identification and Quantification in Food
- Enzyme Structure and Function
- Antimicrobial Peptides and Activities
- Genetically Modified Organisms Research
The First People's Hospital of Changzhou
2024-2025
Soochow University
2024-2025
Ningbo University
2016-2025
Second Affiliated Hospital of Zhejiang University
2025
Taizhou University
2020-2025
First Affiliated Hospital of Soochow University
2024
ZheJiang Academy of Agricultural Sciences
2018
Huazhong University of Science and Technology
2009-2015
Carotenoid content is a primary determinant of wheat nutritional value and affects its end-use quality. Wheat grains contain very low carotenoid levels trace amounts provitamin A content. In order to enrich the in grains, bacterial phytoene synthase gene (CrtB) carotene desaturase (CrtI) were transformed into common cultivar Bobwhite. Expression CrtB or CrtI alone slightly increased transgenic wheat, while co-expression both genes resulted darker red/yellow grain phenotype, accompanied by...
Increasing the provitamin A content in staple crops via carotenoid metabolic engineering is one way to address vitamin deficiency. In this work a combination of methods was applied specifically increase β-carotene wheat by engineering. Endosperm-specific silencing hydroxylase gene (TaHYD) increased 10.5-fold 1.76 μg g–1 endosperm. Overexpression CrtB introduced an additional flux into wheat, accompanied 14.6-fold 2.45 g–1. When "push strategy" (overexpressing CrtB) and "block (silencing...
Objectives Currently, there is limited understanding regarding the prognostic significance of time to progression (TTP) after first remission in multiple myeloma (MM).
Increased intracranial pressure (ICP) is common with viral encephalitis in children which associated complications and prognosis. The optic nerve sheath diameter (ONSD) a new indicator for the assessment of using ultrasound, CT scan MRI imaging. Given influence physical development on ONSD size children, we expect more accurate ONSD/ETD (eyeball transverse diameter) ratio by ultrasound. aim study to determine performance measurement predict ICP occurring evaluate therapeutic effect. Children...
ABSTRACT Vaccination represents a promising approach to combat resistant Klebsiella pneumoniae (KP). However, there is currently no licensed vaccine in the veterinary field. Outer membrane proteins have been proven possess good immunogenicity, but Freund's adjuvant, which commonly used administer protein vaccines, has limitations such as complicated formulation process well tendency cause pain and inflammation animals. Here, we prepared nano‐vaccine based on zeolitic imidazolate framework‐8...
To evaluate the flavor characteristics of Chinese bayberry alcoholic beverages, fermented wine (FBW) and integrated (IBW) were investigated for their volatile soluble profiles using HS-SPME GC-MS UHPLC Q-TOF analyzed with multidimensional statistical analysis, including PCA OPLS-DA. The compounds 1-pentanol, β-caryophyllene isopentanol only detected in IBW. β-caryophyllene, key component bayberry, was found to be most abundant compound IBW (25.89%) 3.73 times more than FBW. levels ethyl...
Issatchenkia orientalis, a non-Saccharomyces yeast that can resist wide variety of environmental stresses, has potential use in winemaking and bioethanol production. Little is known about gene expression or the physiology I. orientalis under ethanol stress. In this study, high-throughput RNA sequencing was used to investigate transcriptome profile response ethanol. 502 transcripts were differentially expressed, which 451 more abundant, 51 less cells subjected 4 h stress (10% v/v). Annotation...
In recent years, Klebsiella pneumoniae (KP) has caused disease outbreaks in different animals, resulting serious economic losses and biosafety concerns. Considering the broad antibiotic resistance of KP, vaccines are most effective tools against infection. However, there is still no KP vaccine available veterinary field. Our results indicate that highly conserved outer membrane phosphoporin (PhoE) immunogenic mice elicits high titers antibodies were shown to be specific for PhoE by...
Both
The transfer of transgenes from 'model' wheat genotypes into elite cultivars using conventional plant breeding is an alternative strategy for improving the dough quality wheat. Thus a cross was made between popular Chinese cultivar Yangzi River down-central area that expresses high-molecular-weight glutenin subunit (HMW-GS): 1Bx7 + 1By8 plus 1Dx2 1Dy12, and model transgenic line B102-1-2 which over-expresses HMW-GS 1Ax1 in L88-31 genetic background includes 1Bx17 By18.F(1) to F(6)...
Fresh-cut produce is at greater risk of Salmonella contamination. Detection and early warning systems play an important role in reducing the dissemination contaminated products. One-step Reverse Transcription Polymerase Chain Reaction (RT-qPCR) targeting tmRNA with or without a 6-h enrichment was evaluated for detection fresh-cut vegetables after storage. LOD one-step RT-qPCR 1·0 CFU per ml (about 100 copies ml) by assessed 10-fold serially diluted RNA from 106 bacteria culture. Then, assay...
Issatchenkia orientalis known as a multi-tolerant non-Saccharomyces yeast, which tolerant environmental stresses, exhibits potential in wine making and bioethanol production. It is essential for the growth of I. to acetic acid mixed cultures with Saccharomyces cerevisiae. In this work, RNA-sequence TMT (Tandem Mass Tag) were used examine comprehensive transcriptomic proteomic profiles response acid. The results showed that 876 genes identified differentially transcribed genome 399 proteins...
Lactic acid bacteria (L34) with antibacterial activity obtained from traditional pickled vegetables was used as a fermented starter in the present study. The changes of product quality and microbial diversity were investigated under spontaneous inoculated fermentations for cooked wax gourd, analysis community conducted by Illumina Miseq sequencing. results showed that pH each sample decreased gradually first 13 days, then increased slightly remained stable. About 6 types organic acids 17...
Abstract Currently, there is limited understanding regarding the prognostic significance of time to progression (TTP) after first remission in multiple myeloma (MM). We conducted a retrospective analysis clinical data from 209 MM patients who experienced disease very good partial (VGPR) or complete (CR) with first-line therapy. These were categorized into subgroups based on TTP. Our findings revealed that G2 group (TTP ≤ 12 months) exhibited shorter median progression-free survival (PFS) and...
Fresh-cut vegetables are exposed to the risk of Salmonella spp. contamination. Effective sterilization methods and early warning systems play important roles in ensuring food safety fresh-cut products. The aim this study was evaluate effect tea polyphenols (TP) combined with thermosonication (TS) treatment on inactivation enterica wax gourd develop estimate models using adaptive neuro-fuzzy inference system (ANFIS) different membership functions (MFs) for predicting S. population during...