- Gynecological conditions and treatments
- Reproductive Biology and Fertility
- Endometriosis Research and Treatment
- Ovarian function and disorders
- Redox biology and oxidative stress
- Mitochondrial Function and Pathology
- FOXO transcription factor regulation
- Sperm and Testicular Function
Second Affiliated Hospital of Zhengzhou University
2016-2020
Nanjing Medical University
2013
Jiangsu Province Hospital
2013
Objective: To compare the influence of various tubal surgeries to ovarian reserve via serum level antimullerian hormone (AMH) and subsequent in vitro fertilization embryo transplantation (IVF-ET) outcome patients with simple infertility.Study design: A prospective cohort study was conducted on 134 IVF cycles undegone by 26 34 cases bilateral unilateral salpingectomy, respectively, 23 oviducts interrupted proximal 51 obstruction without intervention as controls.Results: Serum AMH displayed...
The transcription factor FOXJ3 (Forkhead box J3) is highly expressed in spermatogonia and meiotic spermatocytes within mouse testes. Here, we addressed how might participate spermatogenesis using two conditional knockout models which Foxj3 was deleted from either or spermatocytes. Both exhibited complete male sterility, but distinct etiologies: Deleting Foxj3flox/flox , Mvh-Cre mice caused Sertoli-cell-only syndrome males. Foxj3-deficient were lost as early postnatal Day 4, partially due to...
Objective To investigate the relationship between mitochondrial cytochrome C oxidase 1 genovariation and total fertilization failure. Methods A retrospective comparative study was conducted on 236 cases of Han sperm during freshly conventional in vitro (IVF) cycle part intracytoplasmic injection (Half-ICSI) reproductive center Second Affiliated Hospital Zhengzhou University from July 2011 to May 2017. In experimental group, 57 came couples who had failed IVF; while control 179 normal...