Lilian Gomes de Oliveira

ORCID: 0000-0002-5676-4443
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About
Contact & Profiles
Research Areas
  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • Education Pedagogy and Practices
  • Neurogenesis and neuroplasticity mechanisms
  • Education and Digital Technologies
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Mesenchymal stem cell research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Single-cell and spatial transcriptomics
  • Environmental Sustainability and Education
  • Education and Teacher Training
  • Immune cells in cancer
  • Infectious Encephalopathies and Encephalitis
  • Infection Control and Ventilation
  • Youth, Drugs, and Violence
  • Cancer Cells and Metastasis
  • Innovations in Medical Education
  • SARS-CoV-2 detection and testing
  • Green IT and Sustainability
  • Business and Management Studies
  • Reproductive System and Pregnancy
  • Spinal Cord Injury Research
  • Respiratory viral infections research
  • AI in Service Interactions

Broad Center
2024-2025

University of California, San Francisco
2024-2025

Microsoft (Brazil)
2024

Institute of Biomedical Science
2024

Universidade de São Paulo
2019-2024

The development of the human neocortex is highly dynamic, involving complex cellular trajectories controlled by gene regulation1. Here we collected paired single-nucleus chromatin accessibility and transcriptome data from 38 neocortical samples encompassing both prefrontal cortex primary visual cortex. These span five main developmental stages, ranging first trimester to adolescence. In parallel, performed spatial transcriptomic analysis on a subset illustrate organization intercellular...

10.1038/s41586-024-08351-7 article EN cc-by-nc-nd Nature 2025-01-08

The development of the human neocortex is a highly dynamic process and involves complex cellular trajectories controlled by cell-type-specific gene regulation

10.1101/2024.01.16.575956 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-01-16

COVID-19 causes more than million deaths worldwide. Although much is understood about the immunopathogenesis of lung disease, a lot remains to be known on neurological impact COVID-19. Here, we evaluated immunometabolic changes using astrocytes in vitro and dissected brain areas SARS-CoV-2 infected Syrian hamsters. We show that alters proteins carbon metabolism, glycolysis, synaptic transmission, many which are altered diseases. Real-time respirometry evidenced hyperactivation further...

10.1111/jnc.15679 article EN Journal of Neurochemistry 2022-07-26

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is caused by a virus with wide range of manifestations, varying from asymptomatic to fatal cases, generally short outcome. However, some individuals present long-term viral shedding. We monitored 38 who were mildly affected the SARS-CoV-2 infection. Out total studied population, three (7.9%) showed atypical events regarding duration positivity for RNA detection. In one these previously HIV-positive male patient...

10.3389/fmed.2021.760170 article EN cc-by Frontiers in Medicine 2021-11-26

Abstract Cellular therapy with mesenchymal stem cells (MSCs) is a huge challenge for scientists, as little translational relevance has been achieved. However, many studies using MSCs have proved their suppressive and regenerative capacity. Thus, there still need better understanding of biology the establishment newer protocols, or to test unexplored tissue sources. Here, we demonstrate that murine endometrial-derived (meMSCs) suppress Experimental Autoimmune Encephalomyelitis (EAE)....

10.1042/cs20201544 article EN Clinical Science 2021-05-01

ABSTRACT Coronaviruses belong to a well-known family of enveloped RNA viruses and are the causative agent common cold. Although seasonal coronaviruses do not pose threat human life, three members this family, i.e., SARS-CoV, MERS-CoV recently, SARS-CoV2, may cause severe acute respiratory syndrome lead death. Unfortunately, COVID-19 has already caused more than 4.4 million deaths worldwide. much is better understood about immunopathogenesis lung disease, important information systemic...

10.1101/2021.10.23.465567 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-10-24

A educação para a cidadania global tem ganhado relevância no cenário educacional global, principalmente contexto da implementação dos Objetivos de Desenvolvimento Sustentável (ODS), estabelecidos pelas Nações Unidas em 2015. Esses objetivos visam promover sustentabilidade, igualdade e justiça social, sendo um principais pilares o alcance dessas metas. formação professores, portanto, desempenha papel crucial nesse processo, pois são os educadores que têm poder transformar as novas gerações...

10.9790/487x-2610031323 article PT IOSR Journal of Business and Management 2024-10-01

As redes sociais têm transformado radicalmente a maneira como as pessoas interagem e acessam informações, criando um ambiente propício para construção do conhecimento através da aprendizagem informal. Este artigo examina o impacto das na educação, explorando plataformas Facebook, Instagram, YouTube, outras estão moldando aprendizado fora contexto formal. Através metanálise de estudos recentes, investigamos essas contribuem compartilhamento desenvolvimento habilidades promoção colaborativo. A...

10.9790/487x-2610032435 article PT IOSR Journal of Business and Management 2024-10-01

A educação inclusiva e o conceito de neurodiversidade têm ganhado importância nas últimas décadas, destacando-se a necessidade uma abordagem pedagógica que atenda às particularidades alunos com distúrbios aprendizagem, como Transtorno do Déficit Atenção Hiperatividade (TDAH), dislexia, discalculia, entre outros. Este artigo discute formação professores implementação estratégias pedagógicas adequadas podem promover inclusão neurodiversos escolas, alinhada aos princípios da inclusiva....

10.9790/487x-2610030112 article PT IOSR Journal of Business and Management 2024-10-01

A interseção entre educação e saúde mental tornou-se um tema de crescente relevância nas últimas décadas, à medida que os transtornos ansiedade depressão estudantes têm aumentado forma significativa. Esses afetam não apenas o desempenho acadêmico dos alunos, mas também sua interação social, desenvolvimento emocional bem-estar geral (Silva, 2021; Almeida, 2022). escola, sendo ambiente central na vida jovens, desempenha papel crucial identificação precoce no apoio oferecendo intervenções...

10.9790/487x-2610024152 article PT IOSR Journal of Business and Management 2024-10-01

A educação em nuvem, ou o uso de plataformas baseadas cloud computing no ensino, tem se destacado como uma inovação importante na era digital, permitindo que instituições ensino ofereçam acesso flexível, escalável e colaborativo a conteúdos educacionais ferramentas pedagógicas. Esta abordagem utiliza os recursos da nuvem para armazenar, processar distribuir dados, promovendo um ambiente aprendizado acessível qualquer momento lugar, desde haja conexão à internet. As trazem diversas vantagens,...

10.9790/487x-2610025364 article PT IOSR Journal of Business and Management 2024-10-01

ABSTRACT Zika virus (ZIKV) has the ability to cross placental and brain barriers, causing congenital malformations in neonates neurological disorders adults. However, pathogenic mechanisms of ZIKV-induced complications adults remain unknown. Gas6 is a soluble TAM receptor ligand able promote flavivirus internalization downregulation immune responses. Here we demonstrate high levels serum patients with which correlated genes associated type I IFN responses as consequence Socs1 upregulation....

10.1101/2021.01.27.428402 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-01-28

A pesquisa foi realizada em uma escola municipal de educação infantil, tendo como foco aluna cinco anos que apresenta atraso no desenvolvimento neuropsicomotor.Para a coleta dados, foram feitas filmagens semanais das atividades ocorridas

10.15600/2238-121x/comunicacoes.v17n2p79-91 article PT Comunicações 2010-12-31
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