- School Health and Nursing Education
- Reproductive Biology and Fertility
- Maternal and fetal healthcare
- Trauma and Emergency Care Studies
- Obesity, Physical Activity, Diet
- Health and Medical Studies
- Ovarian function and disorders
- Dupuytren's Contracture and Treatments
- Microfluidic and Capillary Electrophoresis Applications
- Cold Atom Physics and Bose-Einstein Condensates
- 3D Printing in Biomedical Research
- Petroleum Processing and Analysis
- Pickering emulsions and particle stabilization
- Soft tissue tumors and treatment
- Enhanced Oil Recovery Techniques
- Quantum, superfluid, helium dynamics
- Skin Protection and Aging
- Dermatology and Skin Diseases
- Venous Thromboembolism Diagnosis and Management
- Child and Adolescent Health
- Strong Light-Matter Interactions
- Neonatal Respiratory Health Research
- Exercise and Physiological Responses
- Reproductive Physiology in Livestock
- Autoimmune Bullous Skin Diseases
University Hospital of Bern
2015-2024
University of Bern
2017-2024
Heidelberg University
2003-2022
Medizinische Fakultät Mannheim
2011-2022
University Medical Center Hamburg-Eppendorf
2019-2022
Universität Hamburg
2019-2022
Klinik für Frauenheilkunde
2019-2022
Martini-Klinik
2019-2022
University Hospital Heidelberg
2011-2021
University of Mannheim
2009-2021
Abstract Background Autoimmune bullous diseases (AIBD) are rare disorders characterized by autoantibody formation against components of adhesion molecules; in pemphigoid (PD), these proteins hemidesmosomes and basement membrane, important for cell‐matrix skin and/or mucous membranes. Incidences vary considerably between different populations. Objectives To establish a registry prospectively recruiting all AIBD patients geographically well‐defined region Northern Germany (Schleswig‐Holstein)....
Artificial intelligence (AI) is gaining increasing interest in the field of medicine because its capacity to process big data and pattern recognition. Cardiotocography (CTG) widely used for assessment foetal well-being uterine contractions during pregnancy labour. It characterised by inter- intraobserver variability interpretation, which depends on observers' experience. (AI)-assisted interpretation could improve quality and, thus, intrapartal care. raw signals from labouring women were...
Foams produced from non-aqueous media are less common than water-based foams but they play an important role in many industries and engineering processes. The low surface tension of hydrocarbon fluids limits the adsorption activity substances different compounds methods must be considered to generate stabilize oil-based foam. Likewise, destruction unwanted based foam requires specific considerations not found with aqueous systems. Of particular interest petroleum-based foams, which highly...
Recently more and studies have reported high prevalence rates for a 'tanning dependence' among tanning bed users. The authors of these base their argumentation on modified (m) version the CAGE (Cut-down, Annoyed, Guilty Eye-opener) Criteria, initially used alcohol addiction. By means cognitive interviews large population survey, we tested validity mCAGE Criteria above-mentioned that was deduced basis rather small collectives. Firstly, it seems wording so far is inconsistent, misleading...
Are the immune cell profiles and cytokine concentrations in follicular fluid (FF) serum at preovulatory stage different conventional exogenous gonadotrophin stimulated IVF (c-IVF) compared with natural cycle (NC-IVF)?The counts of CD45+ leucocytes T subpopulations FF are c-IVF to NC-IVF.FF-derived cells heterogeneous. Immune involved intra-ovarian processes cytokines required for normal development. Gonadotrophins stimulate regulatory intrafollicular system influence local distribution...
A Bose-Einstein condensate is created in a simple and robust miniature Ioffe-Pritchard trap, the so-called Z trap. This trap results from mere combination of Z-shaped current-carrying wire homogeneous bias field. The experimental procedure allows condensation typically $3\ifmmode\times\else\texttimes\fi{}{10}^{5}$ ${}^{87}\mathrm{Rb}$ atoms $|F=2,$ ${m}_{F}=2〉$ state close to any mirroring surface, irrespective surface structure. Thus it ideally suited as coherent source for traps or cold...
In Europe, little is known about the prevalence of indoor tanning. The aims this study were therefore to estimate sunbed use and identify risk groups motives in a population-based survey. cross-sectional "SUN-Study 2008" ("Sunbed-Use: Needs for Action-Study 2008") was conducted 2008. A total 500 adults, aged 18-45 years, randomly selected asked their tanning practices, motivation perception, compliance staff with international recommendations. Forty-seven percent subjects reported having...
The addition of chemicals is the most widely applied solution to prevent formation foam or destroy it immediately after its generation as a result simplicity and efficiency. Among different that can be used antifoams defoamers, polydimethylsiloxane (PDMS) oils are common, followed by fluorosilicone for severe cases. Nonetheless, there no clear management on selection these additives; therefore, still based trial-and-error basis. For this reason, we have studied properties effectiveness...
Summary von Willebrand disease ( VWD ) is a recognized cause of secondary ankle osteoarthritis OA ). Few studies have examined orthopaedic complications and outcomes in patients treated for end‐stage with total replacement TAR To determine the clinical presentation, intraoperative postoperative evaluate mid‐term outcome . Eighteen mean age 47.3 years (range = 34.0–68.7) were The duration follow‐up was 7.5 2.9–13.2). Intraoperative perioperative recorded. Component stability assessed...
The study was designed to compare the effect of in vitro FSH stimulation on hormone production and gene expression profile granulosa cells (GCs) isolated from single naturally matured follicles obtained natural cycle fertilization (NC-IVF) with conventional gonadotropin-stimulated IVF (c-IVF). Lutein dominant follicle were cultured absence or presence recombinant FSH. cultures run for 48 h six days. Messenger RNA (mRNA) expressions anti-Müllerian (AMH) receptor measured by quantitative...
Pachydermodactyly describes a rare condition of localized fibromatosis, usually symmetrically affecting the interphalangeal joints both hands. We describe case new subtype pachydermodactyly in 14‐year‐old boy, which we term 'unilateral transgrediens'. This atypical pattern is caused by specific mechanical manipulation contributes to completely indolent spectrum pachydermodactyly, and does not need therapy. Therefore it essential misinterpret as an inflammatory state such juvenile idiopathic...
Abstract Purpose Peripartum hemorrhage (PPH) remains one of the main causes maternal mortality worldwide. Treatment includes administration packed red blood cells (RBC) in severe cases and patient management (PBM) may reduce it significantly. In our study, we wanted to retrospectively assess cell PPH evaluate impact PBM Switzerland. Methods Using data from Swiss obstetric hospital registry (Arbeitsgemeinschaft Schweizer Frauenkliniken, ASF), included patients with deliveries 1998 2016. We...
Postpartum hemorrhage (PPH) remains a major cause of maternal morbidity and mortality. While PPH treatment guidelines exist, data on their effect reduction in red blood cell (RBC) transfusions use hemostatic products are scarce. Continuous evaluation management is important to assess potential pitfalls incorporate new options. We retrospectively compared administration RBC before after international guideline implementation. The primary endpoint was for PPH. Secondary endpoints were...
Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality. Routine treatment PPH includes uterotonics, tranexamic acid, curettage, uterine (balloon) tamponade, compression sutures, artery ligation, and, if available, transcatheter arterial embolization (TAE). In cases severe refractory to standard medical surgical management, hysterectomy usually the ultima ratio, equally associated with higher rate complications. addition, this sudden loss fertility, especially in...
We describe an experiment to create a sizable 87Rb Bose–Einstein condensate (BEC) in simple magnetic microtrap, created by current through Z-shaped wire and homogeneous bias field. The BEC is close reflecting surface. It ideal coherent source for experiments with cold atoms surfaces, be it small-volume microtraps or directly studying the interactions between warm
In vitro fertilization involves high dosage gonadotropin stimulation, which apparently has some negative impact on follicular endocrine function. As chorionic stimulation been shown to increase the blood-follicular permeability in animal models, this raises question if such an effect also applies gonadotropins humans, possibly affecting milieu. Follicular fluid and serum were collected at time of aspiration fertilisation without (Natural cycle IVF, n = 24) with (conventional stimulated 31)...
In this paper we present a novel two-channel microfluidic system which acts as an artificial blood capillary vessel to examine the migration steps of cancer cells in microvasculature.The consists polycarbonate and is fabricated by combining hot embossing thermal bonding.The optically transparent allows use live cell fluorescence microscopy.The main feature device that all processes take place under continuous laminar flow conditions at distinct tuneable shear rates.
Fetal electrocardiography (fECG) has gotten widespread interest in the last years as technology for fetal monitoring. Compared to cardiotocography (CTG), current state of art, it can be designed smaller formfactor and is thus suited long-term unsupervised In present study we evaluated a wearable system which based on CSEM's cooperative sensors, versatile that allows measurement multiple biosignals an easy integration into garment or patch. The was tested 25 patients with singleton...