A5004023218- COVID-19 Impact on Reproduction
- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Gestational Diabetes Research and Management
- Phonocardiography and Auscultation Techniques
- Wireless Body Area Networks
- Uterine Myomas and Treatments
- Non-Invasive Vital Sign Monitoring
- Maternal and Perinatal Health Interventions
- Maternal Mental Health During Pregnancy and Postpartum
- Reproductive System and Pregnancy
- COVID-19 and healthcare impacts
- Venous Thromboembolism Diagnosis and Management
- Reproductive Health and Contraception
- Pituitary Gland Disorders and Treatments
- ECG Monitoring and Analysis
- Pregnancy-related medical research
- Breastfeeding Practices and Influences
- Gut microbiota and health
- Lipid metabolism and disorders
- Artificial Intelligence in Healthcare
- Pharmacology and Obesity Treatment
- Prenatal Screening and Diagnostics
- Fetal and Pediatric Neurological Disorders
- Machine Learning in Healthcare
University of Bern
2017-2025
University Hospital of Bern
2018-2024
Olgahospital
2021
Pregnant women may be at higher risk of severe complications associated with the acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which lead to obstetrical complications. We performed a case control study comparing pregnant disease 19 (cases) milder form (controls) enrolled in COVI-Preg international registry cohort between March 24 and July 26, 2020. Risk factors for severity, immediate neonatal outcomes were assessed. A total 926 positive test SARS-CoV-2 included, among 92 (9.9%)...
We report a case of confusingly high soluble fms-like tyrosine kinase 1/placental growth factor (sFlt1/PlGF) ratio in pregnant patient with underlying systemic lupus erythematosus and antiphospholipid syndrome without superimposed pre-eclampsia.
The development and implementation of artificial intelligence (AI) applications in health care contexts is a concurrent research management question. Especially for hospitals, the expectations regarding improved efficiency effectiveness by introduction novel AI are huge. However, experiences with real-life use cases still scarce. As first step towards structuring comparing such experiences, this paper presenting comparative approach from nine European hospitals eleven different possible...
Artificial intelligence (AI) is gaining increasing interest in the field of medicine because its capacity to process big data and pattern recognition. Cardiotocography (CTG) widely used for assessment foetal well-being uterine contractions during pregnancy labour. It characterised by inter- intraobserver variability interpretation, which depends on observers' experience. (AI)-assisted interpretation could improve quality and, thus, intrapartal care. raw signals from labouring women were...
Individuals with SARS-CoV-2 infection and (pre-existing) diabetes, including pregnant women, present more severe morbidity, as compared to non-diabetic subjects. To date, evidence is limited concerning the role of gestational diabetes (GDM) in severity during pregnancy, or vice versa. The aim our study was investigate prevalence GDM a infected population evaluate risk factors for from these patients.A case-control prospective data collection case group 1:2 matching historical controls based...
Misoprostol vaginal insert for induction of labor has been recently reported to be superior dinoprostone in a phase III trial, but never compared misoprostol another galenic form. The aim this study was compare (MVI) with tablets (MVT) term pregnancies. In retrospective cohort we 200 consecutive women induced 200-μg 24-h (Misodel®) historical control 25-μg (Cytotec®) every 4-6 h. Main outcomes variables included induction-to-delivery interval, delivery within 24-h, incidence tachysystole,...
Abstract Introduction Preterm birth is a major cause of neonatal morbidity and mortality. There an urgent need to accurately predict imminent delivery enable necessary interventions such as tocolytic, glucocorticoid, magnesium sulfate administration. We aimed evaluate placental α‐macroglobulin‐1 new diagnostic marker in the prediction preterm birth. Material methods performed prospective observational trial women with intact membranes between 24 +0 36 +6 weeks gestation. included both...
Induction of labour after previous caesarean section (CS) is a challenge for obstetricians due to the increased risk uterine rupture. Common methods induction are balloon catheters and oxytocin as they considered safe. However, effectiveness remains unclear currently available data limited. Therefore, we aimed determine safety catheter or CS.We included 179 consecutive women with CS in this retrospective study. We performed using case Bishop score <6 intact membranes, >6 and/or premature...
Objectives: Management of severe postpartum hemorrhage (PPH) includes transcatheter pelvic arterial embolization (TAE). Data regarding subsequent fertility and obstetrical outcomes is limited, as most derive from TAE in uterine fibroma. The purpose our study was to evaluate the long-term patients undergoing TAE, particularly concerning following pregnancies. Material methods: We included 28 who underwent for PPH at institution between 2009 2018 a retrospective cohort study. were assessed by...
Abstract Background Microbiota composition is fundamental to human health with the intestinal microbiota undergoing critical changes within first two years of life. The developing shaped by maternal seeding, breast milk and its complex constituents, other nutrients, environment. Understanding microbiota-dependent pathologies requires a profound understanding early development healthy infant microbiota. Methods Two hundred fifty pregnant women (≥20 weeks gestation) from greater Bern area will...
Fetal electrocardiography (fECG) has gotten widespread interest in the last years as technology for fetal monitoring. Compared to cardiotocography (CTG), current state of art, it can be designed smaller formfactor and is thus suited long-term unsupervised In present study we evaluated a wearable system which based on CSEM's cooperative sensors, versatile that allows measurement multiple biosignals an easy integration into garment or patch. The was tested 25 patients with singleton...
Objective: to investigate a possible bi-directional association between gestational diabetes (GDM) and the SARS-CoV-2 infection during pregnancy. Design: case-control study with prospective data collection for case group 1:2 matching historical controls Setting: University Hospital of Bern, Switzerland Population: 224 pregnant women: 75 cases pregnancy, matched based on parity, BMI ethnicity. Methods: was diagnosed by RT-PCR. Screening GDM performed 75mg oral glucose tolerance test at 26...
Pregnant women are at increased risk for severe SARS-CoV-2 infection and adverse neonatal outcome, primarily preterm birth stillbirth. Our study aimed to investigate which extent affects placental tissue if viral replication within the placenta is evident, thus there a correlation between damage pregnancy outcome such as
Background: Pregnant women represent a vulnerable population at higher risk of complications infectious diseases. Data regarding the consequences emerging pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during pregnancy are scarce. Recent evidence suggests that pregnant might be disease, while exposed fetuses and newborns could suffer from preterm birth, growth restriction neonatal infections.Methods: We developed an international web registry to allow structured data...
Background: Recent evidence suggests that pregnant women might be at higher risk of severe disease associated with the emerging pandemic acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while exposed fetuses/newborns could suffer from preterm birth, growth restriction and neonatal infections. The magnitude this increased specific factors for severity remains unclear.Methods: We performed a case control study comparing 19 (case) to milder form (controls) enrolled in COVI-Preg...
Objective to evaluate by two-dimensional ultrasound (2D-US) whether there is a difference in the development of Insula Lobe (IL), Sylvian Fissure (SF) and/or SF-ratio [1] between appropriate-for-gestational-age (AGA) fetuses and small for gestational age (SGA) fetuses.