- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- COVID-19 Impact on Reproduction
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Birth, Development, and Health
- Bariatric Surgery and Outcomes
- Trauma and Emergency Care Studies
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and Medication Impact
- Simulation-Based Education in Healthcare
- Reproductive System and Pregnancy
- Prenatal Screening and Diagnostics
- Parvovirus B19 Infection Studies
- COVID-19 and healthcare impacts
- Emergency and Acute Care Studies
- Fetal and Pediatric Neurological Disorders
- Family and Patient Care in Intensive Care Units
- Craniofacial Disorders and Treatments
- Diabetes Management and Education
- Breast Cancer Treatment Studies
- Chronic Disease Management Strategies
- Medical Malpractice and Liability Issues
- Clinical practice guidelines implementation
- Endometriosis Research and Treatment
Institut de Cancérologie de Lorraine
2019-2025
University Hospital of Basel
2011-2024
Universitäts Frauenklinik
2011-2023
Medical University of Vienna
2022-2023
University of Basel
2020-2022
University of Vienna
2022
Pregnant women may be at higher risk of severe complications associated with the acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which lead to obstetrical complications. We performed a case control study comparing pregnant disease 19 (cases) milder form (controls) enrolled in COVI-Preg international registry cohort between March 24 and July 26, 2020. Risk factors for severity, immediate neonatal outcomes were assessed. A total 926 positive test SARS-CoV-2 included, among 92 (9.9%)...
Since the outbreak of coronavirus disease 2019 (COVID-19), there has been a debate whether pregnant women are at specific risk for COVID-19 and it might be vertically transmittable through placenta. We present series five placentas SARS 2 (SARS-CoV-2)-positive who had diagnosed with mild symptoms or asymptomatic before birth. provide detailed histopathologic description morphological changes accompanied by an analysis presence SARS-CoV-2 in placental tissue. All were term deliveries (40th...
SARS-CoV-2 positive pregnant women are at higher risk of adverse outcomes, but little evidence is available on how variants impact that risk. We aim to evaluate maternal and perinatal outcomes among unvaccinated tested for SARS-CoV-2, stratified by pre-Delta, Delta, Omicron periods.This prospective study enrolled from March 2020 September 2022. Exposure the different was defined their periods predominance. The primary outcome severe as either intensive care unit admission, acute respiratory...
Pregnant individuals with coronavirus disease 2019 (COVID-19) are at increased risk of severe disease, prematurity, and stillbirth. In March 2021, vaccination for pregnant women was recommended in Switzerland, expanding this to all May 2021. Our aim assess the safety mRNA COVID-19 vaccines pregnancy.
In obstetrical emergency situations, optimal management requires the immediate coordinated actions of a multi-disciplinary and multi-professional team. This study investigated influence simulation training on four specific skills: self-confidence, handling situation, knowledge algorithms team communication. Clinical were first presented to participants. Training for six situations (shoulder dystocia, postpartum haemorrhage, pre-eclampsia, maternal basic life support, neonatal resuscitation...
Stereotactic radiation therapy (SRT) is on the rise around world. We aimed to provide recommendations streamline and assess medical practices in SRT delivery at treatment unit, while complying with legal obligations concerning safety. conducted an online closed practice survey for heads of radiotherapy departments both nationally comprehensive cancer centers university hospitals throughout France, internationally. The aim was obtain a better understanding how unit managed across different...
A family history of type 2 diabetes mellitus (T2DM) markedly increases an individual's lifetime risk developing the disease. For gestational (GDM), this factor is less well characterized. This study aimed to investigate relationship between T2DM in first- and second-degree relatives women with GDM differences metabolic characteristics at early gestation.This prospective cohort included 1129 pregnant women. broad evaluation was performed before 16 + 0 weeks gestation, including a detailed...
Background We aim to evaluate the impact of prepregnancy overweight on treatment modalities Gestational Diabetes Mellitus (GDM). assessed association increased pregravid Body Mass Index (BMI) with dosing basal and rapid acting insulin as well pregnancy outcome. Methods included 509 gestational diabetic women (normal weight: 200, overweight: 157, obese: 152), attending outpatient clinic at Department Obstetrics Gynecology, Medical University Vienna, in this retrospective study. used a...
Abstract Introduction Previous studies indicated an association between fetal overgrowth and maternal obesity independent of gestational diabetes mellitus (GDM). However, the underlying mechanisms beyond this possible are not completely understood. This study investigates metabolic changes their with neonatal biometry in overweight obese mothers who remained normal glucose‐tolerant during gestation. Material methods In prospective cohort 893 women did develop GDM were categorized according...
Abstract Background Pseudoaneurysm of the uterine artery (UPA) is a rare cause potentially life-threatening hemorrhage during pregnancy and puerperium. It an uncommon condition that mainly occurs after traumatic injury to vessel following pelvic surgical intervention, but also has been reported based on underlying endometriosis. There increased risk developing UPA pregnancy. Diagnosis includes clinical symptoms, with severe abdominal pain confirmed by sonographic or magnetic resonance...
Nonimmune fetal hydrops is a condition defined by abnormal fluid accumulation in two or more body compartments. The aim to evaluate factors associated with adverse outcome diagnosed and investigate the aspects for decision making case of termination pregnancy. Therefore, retrospective data analysis pregnancies complicated non-immune fetalis between 2004 2018 was performed single tertiary referral center. Of 361 hydrops, 183 cases (50.7%), parents decided terminate A strong relationship...
Abstract Objectives The current study aimed to determine the sensitivity and specificity of ultrasound for diagnosis placenta accreta spectrum (PAS) in a universal screening population assesses added value magnetic resonance imaging (MRI). Methods This retrospective analysis evaluated 5219 patients with singleton pregnancies who had standardized (US) examination our unit delivered at institution between 2014 2019. Results A total 181 (3.5%) (100%) suspicion or PAS US. accuracy US detecting...
Abstract Background Although cesarean sections at full dilatation are increasing, training in delivering a deeply impacted fetal head is lacking among obstetricians. The purpose of the study was to implement and evaluate theoretical simulation-based program for this obstetrical emergency. Methods We developed consisting introduction presenting clinical algorithm, on basis available literature, followed by simulation session. used Kirkpatrick’s framework program. A questionnaire distributed,...
Introduction Women with migration background present specific challenges related to risk stratification and care of gestational diabetes mellitus (GDM). Therefore, this study aims investigate the role ethnic origin on developing GDM in a multiethnic European cohort. Methods Pregnant women were included at median age 12.9 weeks assigned geographical regions origin: Caucasian Europe ( n = 731), Middle East North Africa countries (MENA, 195), Asia 127) Sub-Saharan (SSA, 48). At time recruitment...
Objective To investigate the influence of different measurement conditions and ultrasound training level on uterine artery pulsatility index (UtA‐PI) measurements as required for combined first trimester preeclampsia (PE) screening. Methods This was a prospective study consecutive patients with singleton pregnancies presenting an examination between 11 14 weeks' gestation. UtA‐PI were conducted by residents in repeated experienced sonographers thereafter. under conditions. First, trainee...
Background: Pregnant women represent a vulnerable population at higher risk of complications infectious diseases. Data regarding the consequences emerging pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during pregnancy are scarce. Recent evidence suggests that pregnant might be disease, while exposed fetuses and newborns could suffer from preterm birth, growth restriction neonatal infections.Methods: We developed an international web registry to allow structured data...
Background: Recent evidence suggests that pregnant women might be at higher risk of severe disease associated with the emerging pandemic acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while exposed fetuses/newborns could suffer from preterm birth, growth restriction and neonatal infections. The magnitude this increased specific factors for severity remains unclear.Methods: We performed a case control study comparing 19 (case) to milder form (controls) enrolled in COVI-Preg...
Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection may negatively affect glucose metabolism. This study aims to assess levels, prevalence of gestational diabetes mellitus (GDM) and perinatal outcome in women with history COVID-19. To this purpose, a group 65 patients COVID-19 94 control were retrospectively recruited among pregnant who attended the pregnancy outpatient department between 01/2020 02/2022. Glucose data from an oral tolerance test (OGTT), GDM status...
Zusammenfassung Eine geburtshilfliche Simulation gibt den Teilnehmenden die Möglichkeit, realitätsnah klinische Szenarien durchzuspielen und sowohl technische als auch „non technical skills“ im Team zu trainieren. Die anschließende Nachbesprechung evaluiert Simulation. Mit zunehmender Verunsicherung Ausführen geburtshilflicher Manöver durch fehlende praktische Erfahrung Angst vor Verantwortung können Aufbau Erhalt von Simulationstrainings einen attraktiven neuen Weg darstellen, das Interesse...
Conséquences à long terme Du fait de sa prévalence croissante, le diabète gestationnel est l' endocrinopathie la plus fréquente pendant grossesse.Parmi toutes les formes sucré, celui dont nombre augmente rapidement.
Ziel: Gerade im Notfall, wo unter immensem Druck gearbeitet werden muss, ist ein sofortiger und koordinierter Handlungsablauf betreuenden Team, interdiziplinär multiprofessionell, für optimales Management essenziell. Wir stellen Resultate zur Nachhaltigkeit der fachspezifischen Kompetenz in geburtshilflichen Notfallsituationen vor.
Die schwierige fetale Entwicklung bei der Sectio mit vollständig eröffnetem Muttermund wurde als Lücke in Ausbildung von Geburtshelfern identifiziert (1). Mit steigender Rate an Sectiones voller Eröffnung gewinnt dieser geburtshilflichen Notfall zunehmend Bedeutung. technischen Möglichkeiten zur eines im mütterlichen Becken tief eingekeilten fetalen Kopfes, wie die umgekehrte Beckenendlage, sind unserem Setting wenig bekannt. Ziel Studie war Implementierung und Evaluierung theoretischen...