A5089238233- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Pregnancy-related medical research
- Reproductive System and Pregnancy
- Gynecological conditions and treatments
- Ectopic Pregnancy Diagnosis and Management
- Ovarian cancer diagnosis and treatment
- Intestinal and Peritoneal Adhesions
- COVID-19 Impact on Reproduction
- Estrogen and related hormone effects
- Gestational Diabetes Research and Management
- Maternal and Perinatal Health Interventions
- Birth, Development, and Health
- Cancer-related molecular mechanisms research
- Pelvic floor disorders treatments
- Maternal and fetal healthcare
- Medical and Biological Sciences
- Circular RNAs in diseases
- Lymphatic System and Diseases
- Cannabis and Cannabinoid Research
- MicroRNA in disease regulation
- Gestational Trophoblastic Disease Studies
- Vascular Malformations and Hemangiomas
- Pneumocystis jirovecii pneumonia detection and treatment
University of Bern
2014-2024
University Hospital of Bern
2014-2024
University Hospital of Heraklion
2023
Perinatal Institute
2022
Institutes of Science and Development
2016
Klinik für Frauenheilkunde
2015
Recurrence of endometriosis after surgery constitutes a serious challenge. Whether there is an evolution lesion subtypes with each recurrence and whether certain lesions tend to recur faster than others not adequately addressed. Medical records all patients who underwent for between 1997 2018 in the Department Gynecology Obstetrics, University Bern, were reviewed. Inclusion criteria was surgically confirmed recurrence, defined as subsequent previous complete surgical excision lesions. Three...
Individuals with SARS-CoV-2 infection and (pre-existing) diabetes, including pregnant women, present more severe morbidity, as compared to non-diabetic subjects. To date, evidence is limited concerning the role of gestational diabetes (GDM) in severity during pregnancy, or vice versa. The aim our study was investigate prevalence GDM a infected population evaluate risk factors for from these patients.A case-control prospective data collection case group 1:2 matching historical controls based...
Abstract Cellular development is tightly regulated as mature cells with aberrant functions may initiate pathogenic processes. The endometrium a highly regenerative tissue, shedding and regenerating each month. Endometrial stromal fibroblasts are regenerated cycle from mesenchymal stem play pivotal role in endometriosis, disease characterised by endometrial that grow outside the uterus. Why of some women more capable developing into endometriosis lesions not clear. Using isolated, purified...
Endometriosis is a common health problem, affecting 10% of women reproductive age. Laparoscopic surgery proven to relieve pain and improve fertility in with endometriosis. However, identifying peritoneal endometriosis lesions may be difficult due their polymorphic aspects. harbor high degree neovascularization. The visualization tissue perfusion by the additional use near infrared fluorescence imaging indocyanine green (ICG) detection lesions.In single-center, prospective, single-arm pilot...
To assess the diagnostic performance of preoperative application Enzian classification (cEnzian) using surgical findings as reference standard.A prospective international non-interventional study.Twelve endometriosis centres in four European countries (Austria, Germany, Switzerland and Czech Republic).1062 women with surgery.Extent was preoperatively classified cEnzian based on gynaecological examination and/or transvaginal ultrasound (TVS) magnetic resonance imaging (MRI). After subsequent...
To evaluate possible predictive factors for recurrence after laparoscopic segmental bowel resection endometriosis.Cohort study.Academic tertiary referral center.95 symptomatic women with endometriosis who underwent at the Endometriosis clinic, University of Berne, between 2002 and 2012 were enrolled. Since 14 lost to follow-up, 81 formed final cohort. Clinical histological characteristics examined as disease recurrence.Recurrence, defined a subsequent operation due recurrent...
To identify characteristics indicating preoperatively the presence of diaphragmatic endometriosis (DE).Comparison patients with (DE) abdominal without involvement, in a prospective cohort study.Tertiary referral center; center.A total 1372 histologically proven endometriosis.Surgery performed laparoscopically under general anesthesia. All suspected underwent complete bilateral inspection diaphragm.Demographic and clinical pathologic were evaluated using basic descriptive statistics...
Endometriosis is a gynaecological condition with an associated chronic inflammatory response. The ectopic growth of 'lesions', consisting endometrial cells outside the uterine cavity, stimulates response initiating activation macrophages, and resulting in increased cytokine factor concentrations peritoneal fluid (PF). Endometriosis‑associated inflammation long lasting. In patients endometriosis, risk developing ovarian cancer within 10 years, particularly endometrioid or clear cell subtype,...
What are the effects of dienogest (DNG) on midkine (MK) production in women with endometriosis?DNG-mediated down-regulation MK vivo and vitro.DNG is an oral progestin that alleviates painful symptoms endometriosis a favourable tolerability safety profile. Its MK, growth factor plays important role endometriosis, have not yet been investigated.Prospective study 283 patients subjected to laparoscopy for benign pathologies University hospital vitro cultures primary endometrial stromal cells...
Abstract Introduction Progestins are commonly prescribed first‐line drugs for endometriosis. High rates of non‐response and intolerance to these have been previously reported. However, no study date has investigated the characteristics comorbidities patients taking progestins in relation treatment outcomes, so identifying which will respond or tolerate is currently impossible. The purpose this study, therefore, was identify risk factors discontinuation Dienogest (DNG) women with Material...
Higher cesarean section rates and better ultrasound diagnostics have led to a more frequent diagnosis of isthmocele, scar defect. Sometimes, endometriosis is found in the but simultaneous extrauterine isthmocele not yet been reported. Additionally, surgical technique repair subject ongoing controversy. The aim this study analyze possible correlation between uterine (isthmocele) investigate outcome laparoscopic resection rendezvous technique. In single-center retrospective study, we included...
Endocannabinoid (eCB) levels fluctuate in inflammatory conditions and as such may take part endometriosis-associated pain or even endometriosis pathogenesis. In this case-control (23 cases 19 controls) study, targeted lipids were measured the serum peritoneal fluid collected during laparoscopy. Endometriosis was confirmed histologically. Dysmenorrhea, abdominal pain, dyspareunia assessed using Numeric Rating Scale for pain. Steroids, eCBs, related quantified by liquid chromatography-tandem...