A5008414353- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Cervical Cancer and HPV Research
- Cancer Genomics and Diagnostics
- Estrogen and related hormone effects
- Colorectal Cancer Screening and Detection
- Gynecological conditions and treatments
- Pelvic floor disorders treatments
- Pregnancy-related medical research
- Sarcoma Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Breast Cancer Treatment Studies
- Management of metastatic bone disease
- Gestational Trophoblastic Disease Studies
- COVID-19 and healthcare impacts
- Menstrual Health and Disorders
- Traumatic Brain Injury Research
- Medical Practices and Rehabilitation
- Lymphatic System and Diseases
- Music Therapy and Health
- Cancer Treatment and Pharmacology
- Anorectal Disease Treatments and Outcomes
- Intraperitoneal and Appendiceal Malignancies
University Hospital of Bern
2016-2025
University of Bern
2013-2025
Klinik für Frauenheilkunde
2020
ObjectiveDespite its generally favorable prognosis at primary diagnosis, recurrence of endometrial cancer remains an important clinical challenge. The aim this study was to analyze the value molecular classification in recurrent cancer.MethodsThis included patients with who underwent surgical treatment between 2004 and 2015 Karolinska University Hospital, Sweden Bern Switzerland (KImBer cohort) tumor.ResultsOut 594 molecularly classified patients, 101 experienced recurrence, consisting 2...
In endometrial cancer (EMCA), indocyanine green (ICG) sentinel lymph node (SLN) mapping has been reported, mainly in conjunction with robotic surgery.We aimed to evaluate detection rates, sensitivity, and false negative (FN) rate of laparoscopic ICG SLN EMCA, differences surgical outcomes between patients subjected biopsy only versus lymphadenectomy.A retrospective analysis EMCA undergoing ± pelvic (PLND) and/or para-aortic lymphadenectomy (PALND) was performed. Detection rates were...
In 2021, a joint ESGO/ESTRO/ESP committee updated their evidence-based guidelines for endometrial cancer, recommending new risk grouping incorporating both clinicopathologic and molecular parameters. We applied the compared results to those of prior 2016 system.We classified molecularly cohort 604 women diagnosed with cancer using immunohistochemistry TP53 MMR proteins on tissue microarray, as well Sanger sequencing POLE mutations. These results, combined data, allowed patients be grouped...
ObjectiveThe prognostic significance of positive peritoneal cytology in endometrial cancer has long been debated. In 2009, the Fédération Internationale de Gynécologie et d'Obstétrique (FIGO) removed as a staging criterion from system. However, there is still evidence that may decrease survival among patients with cancer. The aim this study was to determine different molecular subgroups.MethodsThis included who underwent primary surgical treatment between 2004 and 2015 at Bern University...
Background: The advantage of robot-assisted hysterectomy over standard laparoscopy remains controversial. Conventional robots offer limited flexibility to the surgeon. novel, Dexter robotic system™, allows integration and easy switch between laparoscopic interface. Objectives: This study’s objective is evaluate feasibility using for hysterectomies by analyzing surgical data intra- postoperative complication rates. Design: Retrospective study. Methods: Women who underwent surgery system at a...
Endometriosis is a common health problem, affecting 10% of women reproductive age. Laparoscopic surgery proven to relieve pain and improve fertility in with endometriosis. However, identifying peritoneal endometriosis lesions may be difficult due their polymorphic aspects. harbor high degree neovascularization. The visualization tissue perfusion by the additional use near infrared fluorescence imaging indocyanine green (ICG) detection lesions.In single-center, prospective, single-arm pilot...
Lymphovascular space invasion (LVSI) is a known prognostic factor for oncological outcome in endometrial cancer patients. However, little about the value of LVSI among different molecular subgroups. The aim this study was to determine dependence from signature.This included patients who underwent primary surgical treatment between February 2004 and 2016 at Karolinska University Hospital, Sweden Bern Switzerland (KImBer cohort). All cases had complete analysis performed on tumor according WHO...
Objective To investigate whether a change in the Fagotti score (ΔFagotti) following neoadjuvant chemotherapy is predictive of resection to no residual disease (R0) and survival women diagnosed with ovarian cancer. Methods Women treated for newly cancer between January 2012 June 2021 at Bern University Hospital were included this retrospective cohort study. scores before after treatment assessed potential association status interval debulking surgery defined as (R0), macroscopic diameter...