Meritxell Royuela

ORCID: 0000-0002-5720-7374
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About
Contact & Profiles
Research Areas
  • Lipoproteins and Cardiovascular Health
  • Antifungal resistance and susceptibility
  • Climate Change and Health Impacts
  • COVID-19 Clinical Research Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Air Quality and Health Impacts
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • SARS-CoV-2 and COVID-19 Research
  • Fungal Infections and Studies
  • Pharmaceutical Economics and Policy
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Genetic Associations and Epidemiology
  • Plant Pathogens and Fungal Diseases
  • Adipokines, Inflammation, and Metabolic Diseases
  • COVID-19 and healthcare impacts
  • Liver Disease Diagnosis and Treatment
  • Retinal Diseases and Treatments
  • Systemic Lupus Erythematosus Research
  • Drug-Induced Adverse Reactions
  • Chemotherapy-related skin toxicity
  • Pharmacovigilance and Adverse Drug Reactions
  • COVID-19 impact on air quality
  • Peripheral Artery Disease Management
  • Vitamin C and Antioxidants Research
  • Genetic factors in colorectal cancer

Althaia
2013-2023

Universitat Rovira i Virgili
2022

Centro de Investigación Biomédica en Red
2022

Institut d'Investigació Sanitària Pere Virgili
2022

Hospital Sant Joan de Déu Barcelona
2017-2018

Abstract Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain association with evolution. Observational cross-sectional study including 1411 hospitalized patients and an available standard prior (n: 1305) or hospitalization 297). usefulness serum total, LDL, non-HDL HDL cholesterol predict prognosis (severe vs mild) was analysed. Patients severe evolution had...

10.1038/s41598-021-86747-5 article EN cc-by Scientific Reports 2021-03-30

Assessing the effect of statin therapy (ST) at hospital admission for COVID-19 on in-hospital mortality.Retrospective observational study. Patients taking statins were 11 years older and had significantly more comorbidities than patients who not statins. A genetic matching (GM) procedure was performed prior to analysis mortality risk. Cox proportional hazards model used cause-specific hazard (CSH) function, a competing-risks Fine Gray (FG) also study direct effects Data from reverse...

10.1093/ehjcvp/pvaa128 article EN other-oa European Heart Journal - Cardiovascular Pharmacotherapy 2020-10-22

Age, sex, race and comorbidities are insufficient to explain why some individuals remain asymptomatic after SARS-CoV-2 infection, while others die. In this sense, the increased risk caused by long-term exposure air pollution is being investigated understand high heterogeneity of COVID-19 infection course.We aimed assess underlying effect NO2 PM10 on severity mortality COVID-19.A retrospective observational study was conducted with 2112 patients suffering infection. We built two sets...

10.1016/j.envint.2021.106930 article EN cc-by Environment International 2021-10-18

The causal role of cholesterol in atherosclerosis was established more than 100 years ago. Along with the fact that higher cholesterol, greater risk atherosclerotic cardiovascular diseases (ASCVD), many randomized controlled trials (RCT) have shown lowering LDL (LDL-C) is associated a lower incidence ASCVD. This impact lipid-lowering therapies on independent drug used, as by several meta-analyses and Mendelian randomization studies. Therefore, concept using “high-intensity statins” should be...

10.56095/eaj.v1i1.10 article EN cc-by-nc-nd European Atherosclerosis Journal 2022-04-05

Familial hypercholesterolemia (FH) is associated with mutations in the low-density lipoprotein (LDL) receptor (LDLR), apolipoprotein B (APOB), and proprotein convertase subtilisin/kexin 9 (PCSK9) genes. A pathological variant has not been identified 30-70% of clinically diagnosed FH patients, a burden LDL cholesterol (LDL-c)-raising alleles hypothesized as potential cause these patients. Our aim was to study distribution weighted LDL-c-raising single-nucleotide polymorphism (SNP) scores...

10.3390/biomedicines8090353 article EN cc-by Biomedicines 2020-09-15

Abstract A retrospective observational study with patients suffering COVID-19 was performed to assess the underlying effect of long-term exposure NO 2 and PM 10 on outcomes. We built multivariate predictive models relationship between The probability either death or severe outcome percentage dead were predicted, while odds ratios effects estimates calculated. Whilst is a variable rather low importance in prediction health outcomes, more important than some stated comorbidities. showed...

10.21203/rs.3.rs-569549/v1 preprint EN cc-by Research Square (Research Square) 2021-06-11

10.1016/j.arteri.2013.05.001 article ES Clínica e Investigación en Arteriosclerosis 2013-06-17
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