A5083409973- Adipokines, Inflammation, and Metabolic Diseases
- Peroxisome Proliferator-Activated Receptors
- Vitamin C and Antioxidants Research
- Climate Change and Health Impacts
- COVID-19 Clinical Research Studies
- Air Quality and Health Impacts
- Adipose Tissue and Metabolism
- Gestational Diabetes Research and Management
- Pituitary Gland Disorders and Treatments
- COVID-19 and healthcare impacts
- Birth, Development, and Health
- Liver Disease Diagnosis and Treatment
- Vitamin K Research Studies
- Diet and metabolism studies
- Epigenetics and DNA Methylation
- Hormonal Regulation and Hypertension
- Kruppel-like factors research
- Diabetes and associated disorders
- Adrenal and Paraganglionic Tumors
- SARS-CoV-2 and COVID-19 Research
- Biomarkers in Disease Mechanisms
- COVID-19 impact on air quality
- Metabolism, Diabetes, and Cancer
- Fibroblast Growth Factor Research
- Lipid metabolism and biosynthesis
Institut d'Investigació Sanitària Pere Virgili
2009-2021
Universitat Rovira i Virgili
2010-2021
Hospital Universitari Joan XXIII de Tarragona
2011-2021
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
2011-2014
Instituto de Salud Carlos III
2014
Abstract Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain association with evolution. Observational cross-sectional study including 1411 hospitalized patients and an available standard prior (n: 1305) or hospitalization 297). usefulness serum total, LDL, non-HDL HDL cholesterol predict prognosis (severe vs mild) was analysed. Patients severe evolution had...
Assessing the effect of statin therapy (ST) at hospital admission for COVID-19 on in-hospital mortality.Retrospective observational study. Patients taking statins were 11 years older and had significantly more comorbidities than patients who not statins. A genetic matching (GM) procedure was performed prior to analysis mortality risk. Cox proportional hazards model used cause-specific hazard (CSH) function, a competing-risks Fine Gray (FG) also study direct effects Data from reverse...
Age, sex, race and comorbidities are insufficient to explain why some individuals remain asymptomatic after SARS-CoV-2 infection, while others die. In this sense, the increased risk caused by long-term exposure air pollution is being investigated understand high heterogeneity of COVID-19 infection course.We aimed assess underlying effect NO2 PM10 on severity mortality COVID-19.A retrospective observational study was conducted with 2112 patients suffering infection. We built two sets...
Context: Zinc-α2-glycoprotein (ZAG) is a soluble protein similar to the class I major histocompatibility complex heavy chain, which has been implicated in lipid catabolism. We hypothesized that ZAG mRNA expression adipose tissue may be linked with lipolytic and adipokine gene have close relationship clinical phenotype. Objectives: The objective of study was analyze human from lean obese subjects. circulating plasma levels its cardiometabolic risk factors were also studied. Design:...
Plasma acutephase protein pentraxin 3 (PTX3) concentration is dysregulated in human obesity and metabolic syndrome. Here, we explore its relationship with insulin secretion sensitivity, markers, adipose tissue PTX3 gene expression. levels were analyzed a cohort composed of 27 lean [body mass index (BMI) ≤ 25 kg/m(2)] 48 overweight (BMI 25-30 kg/m(2)) men (cohort 1). In this cohort, plasma was negatively correlated fasting triglyceride after intravenous oral glucose administration. expression...
Context Lipocalin-2 and adipocyte fatty-acid-binding protein (A-FABP or FABP4) are adipokines potentially involved in the pathophysiology of obesity metabolic syndrome adults. In children, they have been scarcely studied. Objective To analyze lipocalin-2 A-FABP circulating levels before after 2 years a dieting lifestyle intervention prepubertal obese cohort. Design setting Case–control study with prospective follow-up cases for our referral pediatric endocrine outpatient center. Patients...
Context The Activin A-Follistatin system has emerged as an important regulator of lipid and glucose metabolism with possible repercussions on fetal growth. Objective To analyze circulating activin A, follistatin follistatin-like-3 (FSTL3) levels their relationship in pregnant women influence growth neonatal adiposity. Design methods A prospective cohort was studied comprising 207 women, 129 normal tolerance (NGT) 78 gestational diabetes mellitus (GDM) offspring. FSTL3 were measured maternal...
Abstract Background To evaluate the inflammatory axis mediated by tumour necrosis factor‐like weak inducer of apoptosis ( TWEAK ) and its scavenger receptor CD 163 during pregnancy their influence on insulin sensitivity in normal gestational diabetes mellitus GDM ). Materials methods One hundred thirty seven women with one singleton pregnancy, 71 glucose tolerance (NGT) 66 were studied. Glucose metabolism was assessed oral test. Serum concentrations soluble sTWEAK CD163 sCD 163) resistance...
Abstract Objective To evaluate whether the 2016 European Society of Endocrinology (ESE) recommendations for management adrenal incidentalomas accurately classifies those patients who do not require further follow‐up. Design and Methods Single centre retrospective study. From 2010 to 2015, 130 with incidentaloma were evaluated followed‐up. Clinical, analytical radiological data recorded presence comorbidities was assessed. Patients grouped as nonfunctional or subclinical Cushing syndrome...
Abstract A retrospective observational study with patients suffering COVID-19 was performed to assess the underlying effect of long-term exposure NO 2 and PM 10 on outcomes. We built multivariate predictive models relationship between The probability either death or severe outcome percentage dead were predicted, while odds ratios effects estimates calculated. Whilst is a variable rather low importance in prediction health outcomes, more important than some stated comorbidities. showed...