- Lipoproteins and Cardiovascular Health
- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Systems, Economic Evaluations, Quality of Life
- Mobile Health and mHealth Applications
- Heart Failure Treatment and Management
- Pharmaceutical Economics and Policy
- Blood Pressure and Hypertension Studies
- Cancer, Lipids, and Metabolism
- COVID-19 Clinical Research Studies
- Obesity, Physical Activity, Diet
- Antiplatelet Therapy and Cardiovascular Diseases
- Innovations in Medical Education
- Venous Thromboembolism Diagnosis and Management
- Nutritional Studies and Diet
- Adipokines, Inflammation, and Metabolic Diseases
- Health Promotion and Cardiovascular Prevention
- Air Quality and Health Impacts
- Higher Education Teaching and Evaluation
- Health and Lifestyle Studies
- Clinical Reasoning and Diagnostic Skills
- COVID-19 and healthcare impacts
- Climate Change and Health Impacts
- Long-Term Effects of COVID-19
Hospital Militar Central
2025
Universidad Intercultural de Chiapas
2024
Universidad de Costa Rica
2024
Sociedad Española de Nefrología
2022-2023
Centre d'Estudis Avançats de Blanes
2013-2023
University of Girona
2013-2023
Centre Hospitalier Universitaire de Montpellier
2023
Université de Montpellier
2023
Centro de Investigación en Red en Enfermedades Cardiovasculares
2017-2022
Hospital Clínico Universitario de Valladolid
2019-2020
Abstract Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain association with evolution. Observational cross-sectional study including 1411 hospitalized patients and an available standard prior (n: 1305) or hospitalization 297). usefulness serum total, LDL, non-HDL HDL cholesterol predict prognosis (severe vs mild) was analysed. Patients severe evolution had...
Education and cardiovascular disease (CVD) are inversely associated but the mediating factors have not been totally elucidated. Our aim was to analyze role of modifiable risk factors. Cohort study using REGICOR population cohorts. Participants without previous CVD were included (n = 9226). Marginal structural models used association between education incidence at 6 years follow-up. Mediation by (diabetes, dyslipidemia, hypertension, smoking, body mass index, physical activity) assessed...
Assessing the effect of statin therapy (ST) at hospital admission for COVID-19 on in-hospital mortality.Retrospective observational study. Patients taking statins were 11 years older and had significantly more comorbidities than patients who not statins. A genetic matching (GM) procedure was performed prior to analysis mortality risk. Cox proportional hazards model used cause-specific hazard (CSH) function, a competing-risks Fine Gray (FG) also study direct effects Data from reverse...
Familial hypercholesterolemia (FH), the most frequent hereditary cause of premature coronary heart disease (CHD), is underdiagnosed and insufficiently treated.The objectives study were to estimate prevalence FH phenotype (FH-P) describe its clinical characteristics in a Mediterranean population.Data obtained from Catalan primary care system's records database (Catalan acronym: SIDIAP). Patients aged >7 years with at least 1 low-density lipoprotein cholesterol measurement recorded between...
In the statin era, incidence of atherosclerotic cardiovascular diseases (ASCVD) in patients with familial hypercholesterolemia (FH) has not been updated. We aimed to determine ASCVD FH-phenotype (FH-P) and compare it that normal low-density lipoprotein cholesterol (LDL-C) patients. performed a retrospective cohort study using Database Catalan primary care system, including ≥18-year-old an LDL-C measurement. From 1,589,264 available before 2009, 12,823 fulfilled FH-P criteria 514,176 were...
Age, sex, race and comorbidities are insufficient to explain why some individuals remain asymptomatic after SARS-CoV-2 infection, while others die. In this sense, the increased risk caused by long-term exposure air pollution is being investigated understand high heterogeneity of COVID-19 infection course.We aimed assess underlying effect NO2 PM10 on severity mortality COVID-19.A retrospective observational study was conducted with 2112 patients suffering infection. We built two sets...
Background and Objective Coronary heart disease (CHD) is the leading cause of death, smoking its strongest modifiable risk factor. Our aim was to determine impact Spanish 2006 partial smoke-free legislation on acute myocardial infarction (AMI) incidence, hospitalization mortality rates, 28-day case-fatality in Girona, Spain. Methods Using a population-based registry (the REGICOR Study), we compared population hospitalization, pre- post-ban periods (2002–2005 2006–2008, respectively) by...
Congenital heart diseases are structural abnormalities of the with functional repercussions on patient's hemodynamics. At time diagnosis, most patients in childhood, and clinical course exhibits a wide spectrum severity, ranging from mild conditions that do not affect quality life to severe presentations may lead death. Under this concept, we present case 45-year-old patient who was diagnosed childhood ventricular septal defect for which he did receive any treatment or intervention. Despite...
Abstract Familial hypercholesterolemia (FH) is an autosomal dominant disease that has a prevalence of approximately 1/250 inhabitants and the most frequent cause early coronary heart (CHD). We included 1.343.973 women 1.210.671 men with at least one LDL-c measurement from Catalan primary care database. identified 14.699 subjects hypercholesterolemia-Phenotype (FH-P) based on cut-off points by age (7.033 919 women, 5.088 1659 in secondary prevention, respectively). Lipid lower therapy (LLT),...
Bell peppers are one of the most important species consumed and cultivated in Spain. Peppers a source carotenoids phenolic compounds widely associated with biological activities such as antimicrobial, antiseptic, anticancer, counterirritant, cardioprotective, appetite stimulator, antioxidant, immunomodulator. However, undersized damaged fruits usually wasted. Thus, order to evaluate content, Box–Behnken design has been carried out optimize extraction from Capsicum annuum yellow pepper by...
To describe the different falls typology and to investigate whether profiles faller could be identified among a cohort of community-dwelling women aged 75 years older.
Background: Acanthamoeba is a rare cause of encephalitis yet associated with high mortality.Treatment protocols vary greatly and generally include combination therapy across wide spectrum antiinfective classes.Case Description: A 63-year-old male who underwent renal transplantation presented 6 months after depressed level consciousness.Imaging the head computerized tomography showed an enhancing lesion suspicious for brain abscess.Biopsy cysts.The patient was treated sulfadiazine,...
Aromatic l-amino acid decarboxylase deficiency (AADCD) is a rare, early-onset, dyskinetic encephalopathy mostly reflecting defective synthesis of brain dopamine and serotonin. Intracerebral gene delivery (GD) provided significant improvement among AADCD patients (mean age, ≤6 years).We describe the clinical, biological, imaging evolution two ages >10 years after GD.Eladocagene exuparvovec, recombinant adeno-associated virus containing human complimentary DNA encoding AADC enzyme, was...
La empatía es la capacidad de transmitir comprensión hacia las emociones otros individuos. los profesionales sanitarios se ha asociado a mejores resultados clínicos y relación con el paciente. El objetivo del estudio era conocer nivel estudiantes Medicina, su evolución después recibir un curso sobre Entrevista Clínica Comunicación. Estudio longitudinal prospectivo intervención (módulo Comunicación mes duración) sin grupo control. midió cuestionario Índice Reactividad Interpersonal (IRI) que...
In addition to the well established cardiovascular risk factors, evidence suggests a possible role of genetic and non-classical factors in development progression atherothrombosis. We aimed determine relationship classical with candidate gene polymorphisms potentially involved general Mediterranean population.Cross-sectional study.We have determined prevalence (lipid profile, blood pressure, glycaemia, diabetes, smoking, body mass index, menopause family history coronary heart disease)...