A5042149534- Cancer Cells and Metastasis
- 3D Printing in Biomedical Research
- Cellular Mechanics and Interactions
- Wound Healing and Treatments
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- Intraocular Surgery and Lenses
- Tissue Engineering and Regenerative Medicine
- Collagen: Extraction and Characterization
- Polyomavirus and related diseases
- Nanoplatforms for cancer theranostics
- Microtubule and mitosis dynamics
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Hematopoietic Stem Cell Transplantation
- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
- Cancer, Hypoxia, and Metabolism
- Extracellular vesicles in disease
- Ion Channels and Receptors
- Corneal surgery and disorders
- Piperaceae Chemical and Biological Studies
- Electrospun Nanofibers in Biomedical Applications
- Tendon Structure and Treatment
- Additive Manufacturing and 3D Printing Technologies
Universidad de Granada
2020-2025
Instituto de Investigación Biosanitaria de Granada
2021-2025
Regenerative Medicine Institute
2022
Medizinische Hochschule Hannover
2015
The generation of organized 3D tissue constructs that combines cells and photo-crosslinkable biomaterials has been demonstrated using a variety bioprinting technologies. These technologies have inspired the application for "in situ" bioprinting, resulting on hand-held tools called "Biopens" can transfer capabilities directly into hands surgeons. Here, we developed validated biopen ophthalmological applications, specifically corneal stromal regeneration photochemical crosslinking (CXL), as...
Abstract Conventional in vitro cancer models do not accurately reproduce the tumor microenvironment (TME), so three-dimensional (3D)-bioprinting represents an excellent tool to overcome their limitations. Here, two multicellular tri-layered malignant melanoma (MM) composed by stem cells (CSCs) isolated from a MM established cell line or primary-patient derived line, fibroblasts, mesenchymal cells, and endothelial embedded within agarose-collagen type I hydrogel were bioprinted....
Bell peppers are one of the most important species consumed and cultivated in Spain. Peppers a source carotenoids phenolic compounds widely associated with biological activities such as antimicrobial, antiseptic, anticancer, counterirritant, cardioprotective, appetite stimulator, antioxidant, immunomodulator. However, undersized damaged fruits usually wasted. Thus, order to evaluate content, Box–Behnken design has been carried out optimize extraction from Capsicum annuum yellow pepper by...
Nanotechnological platforms offer advantages over conventional therapeutic and diagnostic modalities. However, the efficient biointerfacing of nanomaterials for biomedical applications remains challenging. In recent years, nanoparticles (NPs) with different coatings have been developed to reduce nonspecific interactions, prolong circulation time, improve outcomes. This study aims compare various NP enhance surface engineering more effective nanomedicines. We prepared characterized...
Due to the limitations of current skin wound treatments, it is highly valuable have a healing formulation that mimics extracellular matrix (ECM) and mechanical properties natural tissue. Here, novel biomimetic hydrogel has been developed based on mixture Agarose-Collagen Type I (AC) combined with ECM-related components: Dermatan sulfate (DS), Hyaluronic acid (HA), Elastin (EL) for its application in tissue engineering (TE). Different formulations were designed by combining AC hydrogels DS,...
Due to the limitations of current skin wound treatments, it is highly valuable have a healing formulation that mimics extracellular matrix (ECM) and mechanical properties natural tissue. Here, novel biomimetic hydrogel has been developed based on an Agarose-Collagen Type I (AC) blend combined with ECMrelated components: Dermatan sulphate (DS), Hyaluronic acid (HA), Elastin (EL) for its application in tissue engineering (TE). Different formulations were elaborated AC DS, HA EL. Cell...