A5062855188- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Crystal structures of chemical compounds
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Magnetism in coordination complexes
- Ferrocene Chemistry and Applications
- Organometallic Compounds Synthesis and Characterization
- Crystallography and molecular interactions
- Microwave-Assisted Synthesis and Applications
- Multicomponent Synthesis of Heterocycles
- Inorganic and Organometallic Chemistry
- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- Chemical synthesis and pharmacological studies
- Organometallic Complex Synthesis and Catalysis
- Lanthanide and Transition Metal Complexes
- Protein Interaction Studies and Fluorescence Analysis
- Chemical Synthesis and Analysis
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis of Tetrazole Derivatives
- Advanced biosensing and bioanalysis techniques
- Cell Adhesion Molecules Research
- Pesticide and Herbicide Environmental Studies
University of Havana
2012-2023
Rede de Química e Tecnologia
2019-2020
Universidad de Oviedo
2001
Université Paris-Sud
2000
Centre National de la Recherche Scientifique
2000
Eight Ru(<sc>ii</sc>) complexes were synthesized. The activities against MDA-MB-231 cells include anti-migration, arrest at the sub-G1 phase and cell death by apoptosis.
In this study, half-sandwich Ru(II) complexes containing acylthiourea ligands of the general type [Ru(η6-p-cymene)(PPh3)(S)Cl]PF6 (1m–6m) and [Ru(η6-p-cymene)(PPh3)(S–O)]PF6 (1b–6b) where S/S–O = N',N'-disubstituted were synthesized characterized (via elemental analyses, IR spectroscopy, 1H NMR 13C{1H} X-ray diffractometry), their cytotoxic activity was evaluated. The different coordination modes ligands, monodentately via S bidentately S,O (1b–6b), to ruthenium modulated from synthetic...
In this paper, the title compound was synthesized from N-benzoyl-N′,N′-dibenzylthiourea ligand and potassium tetrachloroplatinate(II), its interaction with human (HSA) bovine (BSA) serum albumin evaluated. Also, crystal structure determined single-crystal X‐ray diffraction, confirming that platinum atom is coordinated two chelated ligands in a distorted square-planar geometry. solid state, Hirshfeld surface analysis emphasizes molecules are connected by non-classical C–H⋯C, C–H⋯S H⋯H...
The complexes cis-bis(N-furoyl-N′,N′-diethylthioureato-k 2O,S)nickel(II) and 2O,S)copper(II) were prepared by the reaction of metal acetate with corresponding acylthiourea derivative. characterized IR, 1H-NMR, 13C-NMR, single-crystal X-ray diffraction. Both show two furoylthiourea ligands bonded to form a four-coordinate complex square-planar geometry. antifungal activity was studied against phytopathogenic fungi Botrytis cinerea Colletotrichum gloeosporioides, responsible for important...
In the crystal structure of title compound, C 20 H 18 N 2 O S, molecules are linked by bifurcated C—H...O hydrogen-bond interactions, giving rise to chains whose links composed alternating centrosymmetrically disposed pairs and characterized R (10) (20) hydrogen-bonding motifs. Also, N—H...S hydrogen bonds form infinite zigzag along [010] direction, which exhibit (4) motif. Hirshfeld surface fingerprint plots were used explore intermolecular interactions in structure. This analysis confirms...
A novel mixed platinum(II) complex with general formula [Pt(PPh 3 ) 2 (L 1 ‐ O,S )]PF 6 has been synthetized and characterized by elemental analysis, molar conductivity, IR NMR ( H, 13 C 31 P) spectroscopic methods. The crystal structure determined single‐crystal X‐ray crystallography. molecule presents an almost ideal square‐planar geometry, the is stabilized weak C–H ··· O F hydrogen bonds, π stacking interactions. steric congestion of ligands described “exact” cone solid angles,...
Six complexes with the general formula [Cu(acylthioureato)(PPh3)2] were synthesized and characterized using spectroscopic techniques (IR, UV/visible, 1D 2D NMR), mass spectrometry, elemental analysis, X-ray diffraction. Interpretation of in vitro cytotoxicity data Cu(I) took into account their stability cell culture medium. DFT calculations showed that NMR properties, such as shielding carbon atoms, are affected by relativistic effects, supported ZORA Hamiltonian theoretical calculations....
Effects of<italic>trans</italic>-[Ru(PPh<sub>3</sub>)2(<italic>N</italic>,<italic>N</italic>-dimethyl-<italic>N</italic>-thiophenylthioureato-k<sub>2</sub>O,S)(bipy)]PF<sub>6</sub>complex on cytotoxicity, the induction of apoptosis and phenotypic reversion tumor cells in different 3D culture techniques.
In the title compound, C(10)H(12)N(2)OS, amide NCO group is twisted relative to thio-ureido SCN(2) group, forming a dihedral angle of 55.3 (2)°. The crystal packing shows inter-molecular N-H⋯S and weak C-H⋯O inter-actions, former giving rise formation centrosymmetric R(2) (2)(8) dimers.
Abstract 1,1-diethylthiourea and 4-methylbenzoic acid were condensed to 1-(4′-methylbenzoyl)-3,3-diethylthiourea in open vessels under microwave irradiation using an unmodified domestic oven. The synthesis was carried out the presence of alumina impregnated with potassium fluoride catalytic amounts N,N-dimethylformamide. yields are noticeably improved comparison classical methods.