Bin Chen

ORCID: 0000-0002-5747-2821
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About
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Research Areas
  • Heart Rate Variability and Autonomic Control
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Acute Myocardial Infarction Research
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Health and Disease Prevention
  • Demographic Trends and Gender Preferences
  • Phonocardiography and Auscultation Techniques
  • Cardiac pacing and defibrillation studies
  • Cancer-related molecular mechanisms research
  • Heart Failure Treatment and Management
  • Mechanical Circulatory Support Devices
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Disease and Adiposity
  • Neurogenetic and Muscular Disorders Research
  • Amyotrophic Lateral Sclerosis Research
  • Cardiovascular and exercise physiology
  • Circular RNAs in diseases
  • Cardiomyopathy and Myosin Studies
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac Valve Diseases and Treatments
  • Antiplatelet Therapy and Cardiovascular Diseases
  • RNA modifications and cancer
  • Reproductive Health and Technologies
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Chongqing Emergency Medical Center
2024

Chongqing University
2024

Zhongshan Hospital
2023

Chongqing Medical University
2020

Shanghai University
2020

Shanghai Sixth People's Hospital
2020

Zhejiang University
2019

Hangzhou First People's Hospital
2017-2019

Xian Yang Central Hospital
2019

Nanjing Medical University
2015-2018

Introduction: It has been commonly accepted that second-hand smoke (SHS) is associated with atherosclerosis and endothelial dysfunction. There growing evidence the changes might begin in childhood. Unfortunately, no study focused on early of Tibetan adolescents exposed to SHS. Aims: We aimed investigate function carotid healthy school-aged male adolescents. Materials methods: All passive smoking participants were students 16 years old male, recruited through middle schools Lhasa city. In...

10.1177/1470320312440901 article EN Journal of the Renin-Angiotensin-Aldosterone System 2012-03-30

Inflammation is implicated in the pathogenesis of calcific aortic valve disease (CAVD) which a major contributor to cardiovascular mortality and lacks non-surgical treatment. The progranulin (PGRN) an important immunomodulatory factor variety inflammatory diseases, including rheumatoid arthritis, osteoarthritis, bowel pneumonia. However, its role calcification remains unknown.We firstly found that PGRN was increased calcified human (AV) tissues. Interestingly, addition full-length (68KD),...

10.1016/j.yjmcc.2020.03.012 article EN cc-by-nc-nd Journal of Molecular and Cellular Cardiology 2020-04-01

Our previous studies identified that the expression of microRNA‑29c (miR‑29c‑3p) was significantly increased in serum pregnant women carrying fetuses with congenital heart disease (CHD) compared normal women. However, mechanism by which miR‑29c‑3p affects development embryonic remained unclear. The aim present study to investigate effect and potential molecular overexpression on P19 cell proliferation, apoptosis differentiation. miR‑29c‑3p‑overexpression protein kinase Bγ (Akt3)‑knockdown...

10.3892/ijmm.2018.4008 article EN cc-by-nc-nd International Journal of Molecular Medicine 2018-11-30

Purpose: Chronic obstructive pulmonary disease (COPD) is associated with increased incidence of arrhythmias, which has been attributed to autonomic dysregulation. Detection function may facilitate stratification COPD patients respect their risk development arrhythmias. Patients and Methods: A total 151 45 non-COPD were included in this study. Heart rate deceleration runs (DRs) detected by dynamic electrocardiogram (ECG); DRs successively occurring 2, 4, or 8 cardiac cycles denoted as DR 2 ,...

10.2147/copd.s234470 article EN cc-by-nc International Journal of COPD 2020-03-01

Objective Pulmonary vein stenosis (PVS) is a serious complication in patients with atrial fibrillation (AF) receiving radiofrequency catheter ablation (RFCA). We therefore examined these patients’ clinical characteristics relation to PVS occurrence. Method retrospectively analyzed the symptoms, diagnostic procedures, and treatment strategies AF who developed after RFCA. Results Among 205 underwent RFCA, five (2.44%) (all men; age 44–64 years; history 12–60 months; 2 paroxysmal AF, 3...

10.1177/0300060519881555 article EN cc-by-nc Journal of International Medical Research 2019-11-10

Abstract Background 2D proximal isovelocity surface area (PISA) method underestimates tricuspid regurgitation (TR) severity largely due to the distortion of flow geometry under low jet velocity. Previous studies demonstrated that confining wall also strained streamline distribution in field. This could add variability when applying PISA TR as presents with wider range effective regurgitant orifice (EROA). Purpose We aim examine (1) impact ventricular constraint region on quantitation and (2)...

10.1093/eurheartj/ehad655.028 article EN European Heart Journal 2023-11-01

Objective To understand the morbidity and epidemiological characteristics of hand, foot mouth disease (HFMD) in Xianyang order to provide evidence for making prevention strategies. Methods The incidence data HFMD from 2013 2016 were collected National Disease Information Management System. The specimens tested by polymerase chain reaction (PCR) results analyzed Statistical Product Service Solutions (SPSS19.0). Results A total 29 662 cases reported 2016, average annual rate was...

10.3760/cma.j.issn.1003-9279.2018.04.011 article EN Chinese Journal of Clinical Hepatology 2018-08-30
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