A5002162827- Advanced Neuroimaging Techniques and Applications
- Genetic Associations and Epidemiology
- Healthcare cost, quality, practices
- Health, Environment, Cognitive Aging
- Dementia and Cognitive Impairment Research
- Psychiatric care and mental health services
- Child and Adolescent Health
- Mental Health Treatment and Access
- Alzheimer's disease research and treatments
- Social Media in Health Education
- Treatment of Major Depression
- Child and Adolescent Psychosocial and Emotional Development
- Posttraumatic Stress Disorder Research
- Empathy and Medical Education
- Cancer Treatment and Pharmacology
- Pharmaceutical industry and healthcare
- MRI in cancer diagnosis
- Bioinformatics and Genomic Networks
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Healthcare Systems and Technology
- BRCA gene mutations in cancer
- Intensive Care Unit Cognitive Disorders
- Pharmaceutical Practices and Patient Outcomes
- Computational Drug Discovery Methods
Newcastle University
1970-2024
Rutgers, The State University of New Jersey
2024
Cardiff University
2016-2023
Newcastle Hospitals - Campus for Ageing and Vitality
2022-2023
National Eczema Association
2022
Kennedy Krieger Institute
2021
Johns Hopkins University
2021
National Health Service
2019
UCL Biomedical Research Centre
2019
Camden and Islington NHS Foundation Trust
2019
Objective: This study used data from the South African Stress and Health Study (SASH) to examine both structural attitudinal barriers treatment initiation among Africans with mental disorders investigate predictors of dropout. Methods: Face-to-face interviews were conducted 4,315 adult living in households or hostel quarters. The interview included a core diagnostic assessment past-12-month assessments disorder severity, service use, treatment. Multivariate logistic regression models...
INTRODUCTION: Despite the high prevalence of low back pain (LBP), identification potentially modifiable generators remains a considerable challenge. Heightened expression Sigma-1 receptor (S1R) chaperone protein has been shown to modulate chronic in patients with hip/knee osteoarthritis, but never explored degenerative spinal tissue. METHODS: Patients undergoing lumbar discectomy or interbody arthrodesis for discogenic LBP (with without concomitant radiculopathy) were included. Inclusion...
Background Fractional anisotropy in the uncinate fasciculus and cingulum may be biomarkers for bipolar disorder even distinctly affected different subtypes of disorder, an area need further research. Aims This study aims to establish if fractional shows differences between healthy controls, patients with type I (BD-I) II (BD-II), their unaffected siblings. Method measures from fasciculus, body parahippocampal were compared tractography methods 40 32 BD-I, 34 BD-II, 17 siblings BD-I 14 BD-II....
Scales measuring cognitive and executive functions are integral to the assessment management of patients with suspected impairment. Some most commonly used tests now subject copyright restrictions. Furthermore, no existing scale assesses both abilities.We aimed develop validate a novel hybrid for use in clinical practice which integrate measures cognition abilities ('Free-Cog').The instrument was devised through national collaboration including health professionals, those lived experience...
Abstract Genome-wide association studies have identified multiple Alzheimer’s disease risk loci with small effect sizes. Polygenic scores, which aggregate these variants, are associated grey matter structural changes. However, genome-wide scores do not allow mechanistic interpretations. The present study explored associations between pathway-specific and structure in younger older adults. Data from two separate population cohorts were used as follows: the Avon Longitudinal Study of Parents...
We investigated the structural brain networks of 562 young adults in relation to polygenic risk for Alzheimer's disease, using magnetic resonance imaging (MRI) and genotype data from Avon Longitudinal Study Parents Children. Diffusion MRI were used perform whole-brain tractography generate connectome, default mode, limbic visual subnetworks. The mean clustering coefficient, betweenness centrality, characteristic path length, global efficiency nodal strength calculated these networks, each...
Corresponding Author: Surg Lt Cdr J Harrison Department of Community Mental Health Portsmouth, HMNB Hants. PO1 3LS What is a Post Traumatic Stress Reaction? Given the substantial scientific and media interest in traumatic events, whether civilian or military, natural man-made it perhaps understandable that such events are often regarded as being likely to leave legacy psychological symptoms. To degree this true. There variety psychiatric conditions which can follow experiences these have...
Abstract Background Anticholinergic medications are drugs that block cholinergic transmission, either as their primary therapeutic action or a secondary effect. Patients with dementia may be particularly sensitive to the central effects of anticholinergic drugs. Anticholinergics also antagonise main treatment, cholinesterase inhibitors. Our study aimed investigate prescribing for patients in UK acute hospitals before and after admission. Methods We included 352 from 17 hospital sites 2019....
Aims and method To ascertain whether patients with proximal femoral fractures were being correctly assessed in line the Mental Capacity Act 2005. Fifty people admitted audited to assess they had given consent treatment accordance Act. A 2005 guidance assessment form was then introduced accompanied by staff training. re-audit undertaken impact. Results The initial audit showed that only one person (2%) been properly assessed. demonstrated use of ensured correct assessment. Clinical...
Dementia is a common condition, and people with dementia occupy around 25% of hospital beds. Commissioning for Quality Innovation (CQUIN) an NHS payment framework that links part English healthcare providers' income to quality improvement. The CQUIN goals are designed encourage the recognition in hospital. Royal Surrey County Hospital, Guildford, introduced new procedures meet targets. Adherence changes was problem. This project aimed improve hospital's implementation strategy. At baseline,...
Aims and method We assessed venous thromboembolism (VTE) risk, barriers to prescribing VTE prophylaxis completion of risk assessment in psychiatric in-patients. This was a cross-sectional study conducted across three centres. used the UK Department Health tool which had been adapted for patients. Results Of 470 patients assessed, 144 (30.6%) were at increased VTE. Patients on old age wards more likely be than those general adult (odds ratio = 2.26, 95% CI 1.51–3.37). higher VTE, auditors...
More students with emotional and behavioral disorders (EBD) than ever before spend most of their time in general education. To increase academic success, EBD need access to empirically supported interventions services. The purpose this systematic review meta-analysis was evaluate strategy effectiveness for K–12 inclusive settings. Identified studies were assessed two approaches evaluating methodological quality multiple methods assessing intervention effects. Results indicated that there is...
Corresponding Author: Surg Cdr N Greenberg, Senior Lecturer in Military Psychiatry, Academic Centre for Defence Mental Health, Weston Education – KCL, Cutcombe Road, London SE5 9RJ Email: sososanta@aol.com Introduction psychiatry is a rather unique speciality. Unlike many other secondary care specialities, military psychiatrists work directly with personnel and do not provide services to the National Health Service. The last article written this Journal about Psychiatry was eight years ago...