- Advanced Photocatalysis Techniques
- TiO2 Photocatalysis and Solar Cells
- Epigenetics and DNA Methylation
- Catalytic Processes in Materials Science
- Cancer-related gene regulation
- Estrogen and related hormone effects
- Electronic and Structural Properties of Oxides
- Additive Manufacturing and 3D Printing Technologies
- Membrane Separation Technologies
- Surface Modification and Superhydrophobicity
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Advanced Sensor and Energy Harvesting Materials
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Gas Sensing Nanomaterials and Sensors
- Additive Manufacturing Materials and Processes
- Catalysis and Oxidation Reactions
- CRISPR and Genetic Engineering
- Genomics and Chromatin Dynamics
- Quantum Dots Synthesis And Properties
- Cellular and Composite Structures
- Synthetic Organic Chemistry Methods
- Surface Chemistry and Catalysis
- Bioactive natural compounds
Chinese Academy of Medical Sciences & Peking Union Medical College
2004-2025
Tongji Hospital
2024-2025
Huazhong University of Science and Technology
2024-2025
Salk Institute for Biological Studies
2019-2024
Northwestern Polytechnical University
2013-2024
Poseida Therapeutics (United States)
2023-2024
Dalian Institute of Chemical Physics
2012-2024
Chinese Academy of Sciences
2013-2024
Lanzhou University of Technology
2024
Beijing Zhongke Science and Technology (China)
2023
Functionally Graded Porous Scaffold (FGPS) becomes an attractive candidate for bone graft due to its combination of better mechanical and biological requirements with the scaffold gradient mimic host tissue. This paper focuses on graded change bio-porous scaffolds in terms physical properties. Gradients three patterns (density, heterostructure cell-size gradients) Gyroid Diamond unit cells were proposed based Triply Periodic Minimal Surfaces (TPMS), fabricated by Selective Laser Melting...
We have investigated the photocatalysis of partially deuterated methanol (CD(3)OH) and H(2)O on TiO(2)(110) at 400 nm using a newly developed apparatus in combination with theoretical calculations. Photocatalyzed products, CD(2)O Ti(5c) sites, H D atoms bridge-bonded oxygen (BBO) sites from CD(3)OH been clearly detected, while no evidence was found. The experimental results show that dissociation occurs stepwise manner which O-H proceeds first is then followed by C-D dissociation....
Clean hydrogen production is highly desirable for future energy needs, making the understanding of molecular-level phenomena underlying photocatalytic both fundamentally and practically important. Water splitting on pure TiO2 inefficient, however, adding sacrificial methanol could significantly enhance photocatalyzed H2 production. Therefore, photochemistry at molecular level provide important insights to its activity. Here, we report first clear evidence derived from time-dependent...
Previous observations of methyl formate (HCOOCH3) during the photo-oxidation methanol (CH3OH) on TiO2 catalysts suggested that photocatalysis could be used to build up complex molecules from a single precursor. We have investigated mechanism HCOOCH3 formation by irradiating CH3OH-adsorbed TiO2(110) surface with 400 nm light at low temperatures. Through detection volatile products after irradiation temperature programmed desorption, we found, as previously reported [Phillips et al. J. Am....
Characterized by high thermal-electrical conductivity and reasonable specific strength, lattice structures of copper alloy have great potential in industrial applications. However, they been rarely studied due to their complicated difficulty fabrication. Based on the ability selective laser melting produce near net shape parts with any complex geometry directly, Cu-Cr-Zr density were manufactured for first time. A series designed a mathematical approach named Triply Periodic Minimal Surfaces...
Technological improvements enable single-cell epigenetic analyses of organ development. We reasoned that high-resolution chromatin accessibility mapping would provide needed insight into the reprogramming and transcriptional regulators involved in normal mammary gland Here, we a resource for murine development from peak fetal stem cell (fMaSC) functional activity late embryogenesis to differentiation adult basal luminal cells. find landscape within individual cells predicts both gene...
Abstract More than 350 million people are chronically infected with hepatitis B virus, and dysfunctional T cell responses contribute to persistent viral infection immunopathogenesis in chronic (CHB). However, the underlying mechanisms of hyporesponsiveness remain largely undefined. Given important role microRNA-146a (miR-146a) diverse aspects lymphocyte function, we investigated potential mechanism miR-146a regulating immune CHB. We found that expression cells is significantly upregulated...
Photoinduced water dissociation on rutile-TiO2 was investigated using various methods. Experimental results reveal that the occurs via transferring an H atom to a bridge bonded oxygen site and ejecting OH radical gas phase during irradiation. The reaction is strongly suppressed as coverage increases. Further scanning tunneling microscopy study demonstrates hydrogen bonds between molecules have dramatic effect reaction. Interestingly, single bond in dimer enhances reaction, while...
Systematically investigating the scores of genes mutated in cancer and discerning disease drivers from inconsequential bystanders is a prerequisite for precision medicine but remains challenging. Here, we developed somatic CRISPR/Cas9 mutagenesis screen to study 215 recurrent "long-tail" breast genes, which revealed epigenetic regulation as major tumor-suppressive mechanism. We report that components BAP1 COMPASS-like complexes, including KMT2C/D, KDM6A, BAP1, ASXL1/2 ("EpiDrivers"),...
Photocatalytic dissociation of deuterated methanol (CD3OD) on both stoichiometric and reduced TiO2(110) surfaces was investigated using the time-dependent two-photon photoemission (2PPE) method, in order to understand effect defects kinetics TiO2(110). By monitoring time evolution photoinduced excited state covered surface, photocatalytic TiO2 surface were observed. The measured photodissociation rate is more than an magnitude faster that surface. Since has considerably subsurface...
Photocatalytic hydrogen evolution and organic degradation on oxide materials have been extensively investigated in the last two decades. Great efforts dedicated to study of photocatalytic reaction mechanisms a variety molecules TiO2 surfaces by using surface science methods under ultra-high vacuum (UHV) conditions, providing fundamental understanding chemical reactions photocatalysis. In this review, we summarize recent progress photocatalysis several important species (water, methanol,...