- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health, psychology, and well-being
- Stress Responses and Cortisol
- Heart Rate Variability and Autonomic Control
- Psychosomatic Disorders and Their Treatments
- Urban Green Space and Health
- Sleep and related disorders
- Exercise and Physiological Responses
- Asthma and respiratory diseases
- Climate Change and Health Impacts
- Thermoregulation and physiological responses
- Psychological Treatments and Assessments
- Genetic Neurodegenerative Diseases
- Food Allergy and Anaphylaxis Research
- Dialysis and Renal Disease Management
- Healthcare professionals’ stress and burnout
- Personality Disorders and Psychopathology
- Long-Term Effects of COVID-19
- Bipolar Disorder and Treatment
- Disaster Response and Management
- Allergic Rhinitis and Sensitization
- Urban and spatial planning
- Grit, Self-Efficacy, and Motivation
- Pediatric health and respiratory diseases
- Infrared Thermography in Medicine
Kansai University of Welfare Sciences
2014-2023
Osaka City University
2009-2020
RIKEN Center for Biosystems Dynamics Research
2019
Yokohama National University
2016
The University of Tokyo
2016
Kansai University
2015
Kansai University of Social Welfare
2015
RIKEN
2014
RIKEN Center for Computational Science
2012-2013
CE Technologies (United Kingdom)
2013
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a disease characterized by chronic, profound, disabling, and unexplained fatigue. Although it hypothesized that brain inflammation involved in the pathophysiology of CFS/ME, there no direct evidence neuroinflammation patients with CFS/ME. Activation microglia or astrocytes related to neuroinflammation. <sup>11</sup>C-(<i>R</i>)-(2-chlorophenyl)-<i>N</i>-methyl-<i>N</i>-(1-methylpropyl)-3-isoquinoline-carboxamide...
Chronic fatigue syndrome (CFS) is a persistent and unexplained pathological state characterized by exertional severely debilitating fatigue, with/without infectious or neuropsychiatric symptoms, lasting at least 6 consecutive months. Its pathogenesis remains incompletely understood. Here, we performed comprehensive metabolomic analyses of 133 plasma samples obtained from CFS patients healthy controls to establish an objective diagnosis CFS. exhibited significant differences in intermediate...
Despite potential significance of fatigue and its underlying components in the occurrence cardiovascular diseases, epidemiologic data showing link are virtually limited. This study was designed to examine whether symptoms or fatigue's a predictor for diseases high-risk subjects with ESRD.788 volunteer patients under hemodialysis therapy (506 male, 282 female) completed survey between October November 2005, follow-up period up 26 months monitor fatal nonfatal events. The questionnaire...
Fatigue is a common complaint among medical students and researchers consider it to be related poor academic outcomes. The authors' goal in the present study was determine whether stress coping strategies were associated with fatigue students. group consisted of 73 second-year healthy attending Osaka City University Graduate School Medicine. Participants completed questionnaire about (Japanese version Chalder Scale), stress, Coping Inventory for Stressful Situations), overwork, nocturnal...
Fatigue is a predictor of cardiovascular events in patients with end-stage renal disease (ESRD) undergoing hemodialysis treatment. We hypothesized that multinutritional support would improve quality life, fatigue symptoms, and potential quantitative measures including endocrine, immune autonomic functions ESRD hemodialysis.Two hundred two were randomly assigned to receive active treatment (containing vitamin B1, B2, niacin, B6, B12, folic acid, C, carnitine, coenzyme Q10, naïve...
In the present study, reliability and construct validity of Japanese version Chalder Fatigue Scale was evaluated as a measure severity fatigue among young students in Japan. A healthy group comprised 27 Grade 6 primary school 28 1 junior high students. The severely fatigued were hospital outpatients with childhood chronic syndrome (n = 21). Principal components analysis varimax rotation identified 4 factors which accounted for 63.2% total variance, original English version. Internal...
Motivation is one of the most important psychological concepts in education and related to academic outcomes medical students. In this study, relationships between personality traits intrinsic motivation were examined students.The study group consisted 119 Year 2 students at Osaka City University Graduate School Medicine. They completed questionnaires dealing with (the Intrinsic Scale toward Learning) Temperament Character Inventory [TCI]).On simple regression analyses, TCI dimensions...
Decrease in intrinsic motivation is a common complaint among elementary and junior high school students, related to poor academic performance. Since grade-dependent development of cognitive functions also influences performance by these we examined whether are the prevalence decrease motivation. The study group consisted 134 students from 4th 6th grades 133 7th 9th grades. Participants completed questionnaire on They performed paper-and-pencil computerized tests measure abilities motor...
The aim of this study was to evaluate the benefit oral ubiquinol-10 supplementation in CFS patients using an open-label and a randomized, double-blinded, placebo-controlled (RCT) study. Twenty with were randomly enrolled 8-week (150 mg ubiquinol-10/day) attending physicians not blinded supplementation. Forty-three assigned receive either mg/day) or placebo every day for 12 weeks. supplementation, total 31 (N = 17 ubiquinol group 14 group) completed beneficial effects observed we conducted...
Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating disease with no molecular diagnostics treatment options. To identify potential markers of this illness, we profiled 48 patients 52 controls for standard laboratory tests, plasma metabolomics, blood immuno-phenotyping transcriptomics, fecal microbiome analysis. Here, identified set 26 that distinguished ME/CFS from healthy controls. Monocyte number, abundance, lipoprotein profiles appeared to be...
We examined relationships among fatigue, sleep quality, and effort-reward imbalance for learning in school children. developed an scale students its reliability validity. Self-administered surveys, including the effort reward leaning fatigue scale, were completed by 1,023 elementary (grades 4-6) 1,361 junior high 7-9) at end of 2006. Effort-reward was associated with a incidence problems both genders. A good relationship family low score boys, friends girls multiple regression analysis....
High-intensity interval training (HIIT) promotes various biological processes and metabolic effects in multiple organs, but the role of extracellular vesicles (EVs) released from a variety cells is not fully understood during HIIT exercise (HIIT-Ex). We investigated changes circulating number proteomic profile EVs to assess effect HIIT-Ex.Seventeen young men (median age, 20 years) were enrolled study. Total duration HIIT-Ex was 4 min. Blood samples collected before (pre-HIIT-Ex), at...
Abstract In 1995, the Hanshin-Awaji area in Japan was damaged severely by a major earthquake. this study, authors administered questionnaires and obtained blood samples to analyze relationships among lifestyle, psychological stress, plasma cortisol levels of victims. The questioned 107 male inhabitants Awaji Island about their lifestyles before after earthquake, presence any symptoms posttraumatic stress disorder, demographic variables. Plasma were determined with enzyme immunoassay....