- Plant Molecular Biology Research
- Plant Reproductive Biology
- Protein Structure and Dynamics
- Advanced Battery Materials and Technologies
- Photosynthetic Processes and Mechanisms
- RNA and protein synthesis mechanisms
- Machine Learning in Bioinformatics
- Advancements in Battery Materials
- Plant-Microbe Interactions and Immunity
- Ziziphus Jujuba Studies and Applications
- MicroRNA in disease regulation
- Silicon Nanostructures and Photoluminescence
- Natural product bioactivities and synthesis
- Plant Virus Research Studies
- Plant Parasitism and Resistance
- Hedgehog Signaling Pathway Studies
- Endoplasmic Reticulum Stress and Disease
- Photochemistry and Electron Transfer Studies
- Bioactive natural compounds
- Flame retardant materials and properties
- Food Quality and Safety Studies
- Nanowire Synthesis and Applications
- Liver physiology and pathology
- Plant Gene Expression Analysis
- Pancreatic function and diabetes
Pennsylvania State University
2024-2025
Ruijin Hospital
2024
Shanghai Jiao Tong University
2024
State Key Laboratory of Modern Optical Instruments
2023
Zhejiang University
2005-2023
Bulacan State University
2021
Zhejiang Chinese Medical University
2008-2019
The mitogen-activated protein kinase (MAPK) cascade consists of three types reversibly phosphorylated kinases, namely, MAPK, MAPK (MAPKK/MEK), and (MAPKKK/MEKK), playing important roles in plant growth, development, defense response. genes have been investigated detail model plants, including Arabidopsis, rice, tomato, but poorly characterized cucumber (Cucumis sativus L.), a major popular vegetable Cucurbitaceae crops, which is highly susceptible to environmental stress pathogen attack.A...
The two-component system (TCS), which comprises histidine kinases (HKs), phosphotransfers (HPs), and response regulator proteins (RRs), plays pivotal roles in regulating plant growth, development, responses to biotic abiotic stresses. TCS genes have been comprehensively identified investigated various crops but poorly characterized tomato. In this work, a total of 65 consisting 20 HK(L)s, six HPs, 39 RRs were from tomato genome. classification, gene structures, conserved domains, chromosome...
Abstract Extreme temperature conditions seriously impair male reproductive development in plants; however, the molecular mechanisms underlying response of anthers to extreme temperatures remain poorly described. The transcription factor phytochrome-interacting factor4 (PIF4) acts as a hub that integrates multiple signaling pathways regulate thermosensory growth and architectural adaptation plants. Here, we report SlPIF4 tomato (Solanum lycopersicum) plays pivotal role regulating cold...
Abstract All‐solid‐state lithium–sulfur batteries (ASSLSBs) have attracted intense interest due to their high theoretical energy density and intrinsic safety. However, constructing durable lithium (Li) metal anodes with cycling efficiency in ASSLSBs remains challenging poor interface stability. Here, a compositionally stable, self‐lithiated tin (Sn)‐carbon (C) composite interlayer (LSCI) between Li anode solid‐state electrolyte (SSE), capable of homogenizing Li‐ion transport across the...
Autogamy in cultivated tomato varieties is a derived trait from wild type plants, which are mostly allogamous. However, environmental stresses can cause morphological defects flowers and hinder autogamy. Under elevated temperatures, plants usually exhibit the phenotype of stigma exsertion, with severely hindered self-pollination fruit setting, whereas inherent mechanism exsertion have been hitherto unknown. Numerous small RNAs (sRNAs) shown to play significant roles plant development stress...
Summary The development of viable pollen determines male fertility, and is crucial for reproduction in flowering plants. Phytochrome interacting factor 3 (PIF3) acts as a central regulator plant growth development, but its relationship with has not been determined. Through genetic, histological transcriptomic analyses, we identified an essential role SlPIF3 regulating tomato ( Solanum lycopersicum ) development. Knocking out using clustered regularly interspaced short palindromic...
Abstract Singlet fission (SF) is an appealing process where one photoexcited singlet transforms to two triplets, which can overcome thermalization energy loss and improve solar cell efficiency. However, it remains unclear how intermolecular coupling, subject molecular stacking, controls SF pathways dynamics. Here, we prepared polymorph rubrene single crystals with different stacking geometries, including orthorhombic (Orth.), triclinic (Tri.), monoclinic (Mono.) phases. By micro‐area...
Abstract Background Hepatic fibrosis is the final endpoint for most chronic liver diseases and remains a significant public health problem worldwide. Icariin, naturally occurring flavonol glucoside, has been reported to exhibit protective effects on injury alleviate fibrosis. However, underlying detail molecular mechanism not fully revealed. Methods Mouse primary hepatic stellate cells (HSCs) carbon tetrachloride (CCL 4 )‐induced model in mice were used as vitro vivo models this study. The...
Abstract Given the rapid growth in number of sequences without known structures, it is becoming increasingly important to not only accurately define protein structural domains but also predict domain boundaries from amino‐acid sequence alone. In this article, we present a Back‐Propagation (BP) neural network method using 9 different profiles, based on chemical, physical, and statistical properties, boundary two‐domain proteins one dimensional sequences. We have achieved an accuracy 69% with...
In this paper, we use the spin-on-dopant technique for phosphorus doping to improve photoelectric properties of soft-chemical-prepared silicon nanosheets. It was found that luminescence intensity and lifetime doped samples approximately 4 fold undoped samples, due passivation surface defects by doping. Meanwhile, combined with high-temperature heat treatment can reduce resistivity multilayer nanosheets 6 compared as-prepared samples. conclusion, our work brings one step closer practical...
Understanding how protein folds into a functional native structure is arguably one of the most challenging problems remaining in computational biology. Currently, folding mechanism often characterized by calculating free energy landscape terms various reaction coordinates such as fraction contacts, radius gyration, RMS deviation from and so on. In this paper, we present wavelet approach towards understanding global state changes during folding. The based on analysis trajectories to identify...
An accurate solvation model is essential for computer modeling of protein folding and other biomolecular self-assembly processes. Compared to explicit solvent models, implicit such as the Poisson-Boltzmann (PB) with accessible surface area (PB/SA), offer a much faster speed—the most compelling reason popularity these models. Since models typically use empirical parameters, atomic radii tensions, an optimal fit parameters crucial final accuracy properties free energy energy. In this paper, we...
Background The WFS1 gene encodes the protein wolframin, which is crucial for maintaining endoplasmic reticulum homeostasis. Variants in this are predominantly associated with Wolfram syndrome and have been implicated other disorders such as diabetes mellitus psychiatric diseases, increases rate of clinical misdiagnosis. Methods Patients were diagnosed early-onset unclassified according to their laboratory data. We performed whole-exome sequencing (WES) 165 patients, interpreting variants...