A5067244908- Spondyloarthritis Studies and Treatments
- Bone and Joint Diseases
- Psoriasis: Treatment and Pathogenesis
- Systemic Sclerosis and Related Diseases
- Bone health and osteoporosis research
- Therapeutic Uses of Natural Elements
- Medication Adherence and Compliance
- Vitamin D Research Studies
- Pharmaceutical studies and practices
- Autoimmune and Inflammatory Disorders Research
- Autoimmune Bullous Skin Diseases
- Research on Leishmaniasis Studies
- Systemic Lupus Erythematosus Research
- Safe Handling of Antineoplastic Drugs
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Adolescent and Pediatric Healthcare
- Autoimmune and Inflammatory Disorders
- Nutrition and Health in Aging
- Pregnancy and Medication Impact
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- S100 Proteins and Annexins
- Parvovirus B19 Infection Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
Hospital Universitario Doctor Peset
2013-2023
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
2018-2020
This article compares gravimetry vs. high-performance liquid chromatography (HPLC) as quality control (QC) methods for paclitaxel, docetaxel and oxaliplatin preparations. We aimed at assessing the preparation method reliability in our hospital, evaluating compounding accuracy estimating influence of personnel training standardized homogenization on accuracy. Agreement, correlation, concordance, precision between were evaluated each drug. Conforming percentages (CPs) different tolerance...
Purpose To evaluate the cost-effectiveness of addition bevacizumab to irinotecan-fluorouracil (Douillard regimen-CPT-FUFA-) in first-line treatment metastatic colorectal cancer a single-institution population. Methods Controlled, nonrandomized retrospective observational study. Treatment-naïve patients received CPT-FUFA (January 2000-December 2003; control group) and bevacizumab_CPT-FUFA 2007-December 2010; study group). Variables related to: patient, clinical response (number disease...
In patients with axial spondyloarthritis, vertebral fracture risk is elevated and not always correlated bone mineral density (BMD). Trabecular score (TBS) may offer some advantages in the assessment of these patients. The primary objective this study was to compare TBS BMD between spondyloarthritis depending on their status. Secondary objectives were estimate prevalence morphometric fractures, explore factors associated fracture, as well interference syndesmophytes TBS.A cross-sectional...
<h3>Background</h3> Plasma d-dimer (DD) has proven to be a reliable marker of systemic prothrombotic state and its measurement might helpful in predicting cardiovascular events even mortality across broad variety diseases. An association between high levels DD macrovascular disease, diffuse cutaneous involvement active disease been suggested patients with SSc. <h3>Objectives</h3> To determine the usefulness as explore relation other features biomarkers <h3>Methods</h3> Descriptive...
<h3>Background:</h3> Medication non-adherence is associated with treatment failure. Some authors show a positive relationship between patient activation and both, adherence to for chronic conditions improved outcomes. <h3>Objectives:</h3> To present preliminary results of study measuring biological therapy its the Patient Activation Measure (PAM) in outpatient setting. <h3>Methods:</h3> Ambispective longitudinal observational descriptive general tertiary university hospital. Patients on same...
<h3>Background</h3> Obesity is a comorbid condition in patients with psoriasis which tends to be less common psoriatic arthritis (PsA). In the general population, obesity associated increased inflammatory load and vascular risk, hypovitaminosis D. <h3>Objectives</h3> To explore relationship between disease activity, damage, serum concentrations of vitamin D (25OHD) bone mineral density (BMD) PsA. <h3>Methods</h3> Descriptive cross-sectional study. Patients PsA peripheral joint involvement...
<h3>Background:</h3> Medication non-adherence has been associated with treatment failure in chronic inflammatory conditions. A positive relationship between patient activation and adherence to improved clinical outcomes shown for <h3>Objectives:</h3> To measure biological therapies targeted synthetic DMARD (tsDMARD), their the Patient Activation Measure (PAM) therapy related factors, arthropathies. <h3>Methods:</h3> Cross-sectional observational descriptive study a general tertiary...
<h3>Background</h3> Patients with psoriatic arthritis (PsA) have a higher prevalence of classical vascular risk factors (CVRF) and early atherosclerosis determined by chronic inflammation. <h3>Objectives</h3> To study the evolution over time different damage evaluation measures in patients PsA investigate related to these changes. <h3>Methods</h3> Pre-post longitudinal analytical components. peripheral joint involvement were included. Demographic (sex, age), clinical [duration disease,...
<h3>Background</h3> Patients with inflammatory rheumatic diseases, such as rheumatoid arthritis (RA) or psoriatic (PsA), have a higher cardiovascular risk than the general population. There are data in other pathologies about role of leukocyte adhesion on endothelial damage. <h3>Objectives</h3> To evaluate relationship between and subclinical vascular damage patients RA PsA. <h3>Methods</h3> Observational, cross-sectional exploratory study. PsA who had at least one previous study were...
<h3>Background:</h3> Some studies indicate that psoriatic arthritis (PsA) patients have increased bone loss due to chronic inflammation, but data in the Spanish population is scarce. <h3>Objectives:</h3> To study evolution over time of mineral density (BMD) with PsA and investigate factors related these changes. <h3>Methods:</h3> We included peripheral joint involvement. They were treated at Doctor Peset University Hospital a 3-year follow-up was carried out. All underwent densitometry...
Background There are increasingly data about the usefulness of calprotectin levels in chronic inflammatory arthritis and its relationship with prognostic factors. However, few available on role diagnosis acute arthritis. Objectives To evaluate possible testing plasma synovial fluid (SF) as a predictor final behind an mono or oligoarthritis. Methods Longitudinal observational study. We included non-consecutive patients referred to rheumatology emergency department suspected oligoarthritis for...
<h3>Background</h3> Patients with chronic inflammatory disease in treatment immunosuppressants have an increased risk of opportunistic infections, including leishmaniasis. <h3>Objectives</h3> To describe a multicenter case series leishmaniasis patients diseases treated immunosuppressants. analyze factors related to the infection. <h3>Methods</h3> Observational retrospective study. We reviewed clinical history immunosuppressants, who were diagnosed between 2007 and 2018. Demographic (age,...
Background: Rituximab (RTX) is effective in improving skin affection patients with diffuse cutaneous systemic sclerosis (DcSSc). However, there are few data on early use of this drug. Objectives: To evaluate RTX effectiveness for disease DcSSc less than 3 years evolution. Methods: Multicenter, observational and retrospective study. Patients starting within since first non-Raynaud symptom were recruited. Demographic variables, time duration at the beginning RTX, immune pattern treatment...
Background: In axial spondyloarthritis (axSpA) the risk of vertebral fracture is increased, not always corresponding with values bone mineral density (BMD). One possible explanation that syndesmophytes interfere these values. We consider whether evaluation trabecular microarchitecture by an accessible methodlike Trabecular Bone Score (TBS), does involve additional irradiation neither seem to be influenced presence syndesmophytes, may advantage estimate fracture. Objectives: To prevalence...
Background: Arthritis of viral aetiology is considered the most frequent cause acute arthritis. The common etiologic agent parvovirus B19 (B19). Besides, other viruses can lead to inflammatory joint disease, such as Epstein-Barr virus (EBV), Cytomegalovirus (CMV), Human immunodeficiency (HIV), Rubella, Mumps, Hepatitis B and C (HBV HCV) Chikungunya (in transcontinental travellers or immigrants). Objectives: To describe epidemiological characteristics, clinical analytical course, evolution...
Background: There are few data about variations in bone metabolism associated with weight loss obese patients undergoing bariatric surgery. Objectives: To assess the influence on of surgery morbidly patients. Methods: Longitudinal pre-post study analytical components. All were, prior to this, referred Rheumatology Department. In all cases, baseline characteristics were collected and a complete metabolic densitometry (BMD) requested. This same was repeated one year later, window period ± 3...
Background: Psoriatic arthritis (PsA) is associated with insufficent levels of vitamin D (25OHD) and an increased cardiovascular risk. Several studies, have shown inverse relationship between 25OHD damage. Objectives: To study the vascular damage, as well its possible influence on progression, in patients PsA. Methods: Pre-post longitudinal analytical components. PsA peripheral joint involvement were included. Demographic (sex, age), clinical [follow-up time, DAPSA, current treatment, body...
Background: Treatment of calcinosis associated with systemic sclerosis (SSc) mainly involves the use therapies, which often have limited efficacy. However, little attention has been paid to local treatment, is especially useful when skin ulcers. Objectives: To show our experience topical sodium thiosulfate (TST) for treatment calcinosis-associated cutaneous ulcers in patients SSc. Methods: Descriptive analysis a case series SSc and treated TST. Wound management procedure : wounds...
Background: Several studies have shown an inverse relationship between vitamin D levels (25OHD) and disease activity in patients with rheumatoid arthritis (RA). However, the existing data psoriatic (PsA) are poor, they use DAS28 index as a peripheral joint marker by extrapolation RA. Objectives: To analyze 25OHD levels, functional capacity PsA. Methods: Transversal, observational, descriptive study. We included PsA involvement. collected demographic variables (gender, age), clinical...
Background: The delay in the diagnosis of axial spondyloarthropathies (AxSp), with morbidity and economic burden that this entails, is well known 1,2 . According to 2017 Atlas spondyloarthritis Spain 3 , mean diagnostic was 8,5 years, an average total cost per patient 659,8€ including medical consultations complementary tests until diagnosis. However, nowadays there are still many patients who incorrectly referred from general practitioner (GP) despite showing typical features AxSp....