A5023873922- Spondyloarthritis Studies and Treatments
- Psoriasis: Treatment and Pathogenesis
- Systemic Sclerosis and Related Diseases
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Bone and Joint Diseases
- Therapeutic Uses of Natural Elements
- Vitamin D Research Studies
- Autoimmune Bullous Skin Diseases
- Bone health and osteoporosis research
- S100 Proteins and Annexins
- Dermatologic Treatments and Research
- Cardiovascular Disease and Adiposity
- Nutrition and Health in Aging
- Medical Imaging and Analysis
- Healthcare Systems and Public Health
- Musculoskeletal Disorders and Rehabilitation
- Medication Adherence and Compliance
- Bariatric Surgery and Outcomes
- Parvovirus B19 Infection Studies
- Reproductive System and Pregnancy
- Adolescent and Pediatric Healthcare
- Pregnancy and Medication Impact
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Dermatological and Skeletal Disorders
Hospital Universitario Doctor Peset
2017-2024
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
2018-2019
Center for Rheumatology
2017
Secukinumab is a biologic disease-modifying antirheumatic drug (bDMARD) that has demonstrated efficacy in the treatment of axial spondyloarthritis (axSpA, i.e., ankylosing spondylitis and non-radiographic axSpA) across various clinical trials. However, data secukinumab practice still limited. Here, we aimed to provide real-world on use, effectiveness, persistence axSpA.
Psoriatic arthritis (PsA) is a complex and heterogeneous inflammatory disease. Secukinumab, biologic disease-modifying antirheumatic drug (bDMARD), has extensive clinical evidence of efficacy safety in the treatment PsA but data practice are still limited. This study aims to provide real-world on secukinumab use, effectiveness, persistence PsA.A retrospective, multicenter was conducted patients diagnosed with treated up June 2021 at 12 centers Valencian Community (Spain). Data DAS28-CRP,...
<h3>Background</h3> RA patients have a higher risk of vascular events, especially cardiac ones. Besides, mortality in these is 54% than the general population. Nowadays, we non-invasive techniques that allow us to detect subclinical damage. <h3>Objectives</h3> To describe affection sample and explore its relationship with development events. <h3>Methods</h3> Ambispective observational study analytical components. We included, consecutively, controlled tertiary hospital. gathered demographic...
<h3>Background</h3> Accelerated atherosclerosis (AE) and increased arterial stiffness are comorbidities of rheumatoid arthritis (RA) related to the inflammatory burden disease, as well certain clinical genetic characteristics disease. There is controversy about role ACPA in development AE these patients. <h3>Objectives</h3> To explore relation between RF titres subclinical vascular damage RA <h3>Methods</h3> Descriptive cross-sectional study with analytical components. A total 244 patients...
<h3>Background</h3> Psoriatic arthritis (PsA) is a disease associated with an increased cardiovascular (CV) risk, due to early atherosclerosis, which comparable rheumatoid population. However, there lack of studies that evaluate the progression subclinical atherosclerosis over year in these patients. <h3>Objectives</h3> To explore vascular damage by different techniques patients PsA and factors related changes. <h3>Methods</h3> Pre-post study analytical components. 44 (CASPAR criteria)...
<h3>Background</h3> Plasma d-dimer (DD) has proven to be a reliable marker of systemic prothrombotic state and its measurement might helpful in predicting cardiovascular events even mortality across broad variety diseases. An association between high levels DD macrovascular disease, diffuse cutaneous involvement active disease been suggested patients with SSc. <h3>Objectives</h3> To determine the usefulness as explore relation other features biomarkers <h3>Methods</h3> Descriptive...
<h3>Background</h3> Obesity is a comorbid condition in patients with psoriasis which tends to be less common psoriatic arthritis (PsA). In the general population, obesity associated increased inflammatory load and vascular risk, hypovitaminosis D. <h3>Objectives</h3> To explore relationship between disease activity, damage, serum concentrations of vitamin D (25OHD) bone mineral density (BMD) PsA. <h3>Methods</h3> Descriptive cross-sectional study. Patients PsA peripheral joint involvement...
<h3>Background:</h3> Medication non-adherence has been associated with treatment failure in chronic inflammatory conditions. A positive relationship between patient activation and adherence to improved clinical outcomes shown for <h3>Objectives:</h3> To measure biological therapies targeted synthetic DMARD (tsDMARD), their the Patient Activation Measure (PAM) therapy related factors, arthropathies. <h3>Methods:</h3> Cross-sectional observational descriptive study a general tertiary...
<h3>Background:</h3> There is none defined competences framework for Rheumatology Nursing at the moment in Spain. This fact leads to an heterogeneous roles and interventions each department which has not ever been described nor quantified. <h3>Objectives:</h3> To describe quantify rheumatology Valencian Region (Spain). <h3>Methods:</h3> A descriptive study was performed by completion of online questionnaire with a list clinical research intervention. The sent Head Department 33 public...
<h3>Background</h3> Patients with psoriatic arthritis (PsA) have a higher prevalence of classical vascular risk factors (CVRF) and early atherosclerosis determined by chronic inflammation. <h3>Objectives</h3> To study the evolution over time different damage evaluation measures in patients PsA investigate related to these changes. <h3>Methods</h3> Pre-post longitudinal analytical components. peripheral joint involvement were included. Demographic (sex, age), clinical [duration disease,...
<h3>Background</h3> Patients with inflammatory rheumatic diseases, such as rheumatoid arthritis (RA) or psoriatic (PsA), have a higher cardiovascular risk than the general population. There are data in other pathologies about role of leukocyte adhesion on endothelial damage. <h3>Objectives</h3> To evaluate relationship between and subclinical vascular damage patients RA PsA. <h3>Methods</h3> Observational, cross-sectional exploratory study. PsA who had at least one previous study were...
<h3>Background:</h3> Some studies indicate that psoriatic arthritis (PsA) patients have increased bone loss due to chronic inflammation, but data in the Spanish population is scarce. <h3>Objectives:</h3> To study evolution over time of mineral density (BMD) with PsA and investigate factors related these changes. <h3>Methods:</h3> We included peripheral joint involvement. They were treated at Doctor Peset University Hospital a 3-year follow-up was carried out. All underwent densitometry...
Background There are increasingly data about the usefulness of calprotectin levels in chronic inflammatory arthritis and its relationship with prognostic factors. However, few available on role diagnosis acute arthritis. Objectives To evaluate possible testing plasma synovial fluid (SF) as a predictor final behind an mono or oligoarthritis. Methods Longitudinal observational study. We included non-consecutive patients referred to rheumatology emergency department suspected oligoarthritis for...
Background: Rituximab (RTX) is effective in improving skin affection patients with diffuse cutaneous systemic sclerosis (DcSSc). However, there are few data on early use of this drug. Objectives: To evaluate RTX effectiveness for disease DcSSc less than 3 years evolution. Methods: Multicenter, observational and retrospective study. Patients starting within since first non-Raynaud symptom were recruited. Demographic variables, time duration at the beginning RTX, immune pattern treatment...
Background: In axial spondyloarthritis (axSpA) the risk of vertebral fracture is increased, not always corresponding with values bone mineral density (BMD). One possible explanation that syndesmophytes interfere these values. We consider whether evaluation trabecular microarchitecture by an accessible methodlike Trabecular Bone Score (TBS), does involve additional irradiation neither seem to be influenced presence syndesmophytes, may advantage estimate fracture. Objectives: To prevalence...
Background: Arthritis of viral aetiology is considered the most frequent cause acute arthritis. The common etiologic agent parvovirus B19 (B19). Besides, other viruses can lead to inflammatory joint disease, such as Epstein-Barr virus (EBV), Cytomegalovirus (CMV), Human immunodeficiency (HIV), Rubella, Mumps, Hepatitis B and C (HBV HCV) Chikungunya (in transcontinental travellers or immigrants). Objectives: To describe epidemiological characteristics, clinical analytical course, evolution...
Background: There are few data about variations in bone metabolism associated with weight loss obese patients undergoing bariatric surgery. Objectives: To assess the influence on of surgery morbidly patients. Methods: Longitudinal pre-post study analytical components. All were, prior to this, referred Rheumatology Department. In all cases, baseline characteristics were collected and a complete metabolic densitometry (BMD) requested. This same was repeated one year later, window period ± 3...
Background: Psoriatic arthritis (PsA) is associated with insufficent levels of vitamin D (25OHD) and an increased cardiovascular risk. Several studies, have shown inverse relationship between 25OHD damage. Objectives: To study the vascular damage, as well its possible influence on progression, in patients PsA. Methods: Pre-post longitudinal analytical components. PsA peripheral joint involvement were included. Demographic (sex, age), clinical [follow-up time, DAPSA, current treatment, body...
Background: Treatment of calcinosis associated with systemic sclerosis (SSc) mainly involves the use therapies, which often have limited efficacy. However, little attention has been paid to local treatment, is especially useful when skin ulcers. Objectives: To show our experience topical sodium thiosulfate (TST) for treatment calcinosis-associated cutaneous ulcers in patients SSc. Methods: Descriptive analysis a case series SSc and treated TST. Wound management procedure : wounds...
Background: Methotrexate (MTX) is the first choice disease-modifying anti-rheumatic drug (FAME) in treatment of rheumatoid arthritis among other rheumatic diseases. It therefore very important that patients are aware this and have an adequate management it. Objectives: The development a recommendation leaflet for with diseases MTX. Methods: A systematic review literature was conducted, defining criteria inclusion exclusion content. coordinators work generated preliminary recommendations were...
Background: Several studies have shown an inverse relationship between vitamin D levels (25OHD) and disease activity in patients with rheumatoid arthritis (RA). However, the existing data psoriatic (PsA) are poor, they use DAS28 index as a peripheral joint marker by extrapolation RA. Objectives: To analyze 25OHD levels, functional capacity PsA. Methods: Transversal, observational, descriptive study. We included PsA involvement. collected demographic variables (gender, age), clinical...