- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Congenital Diaphragmatic Hernia Studies
- Organ Transplantation Techniques and Outcomes
- Abdominal Trauma and Injuries
- Gastrointestinal disorders and treatments
- Neuroblastoma Research and Treatments
- Esophageal and GI Pathology
- Abdominal Surgery and Complications
- Infective Endocarditis Diagnosis and Management
- Biliary and Gastrointestinal Fistulas
- Phagocytosis and Immune Regulation
- Gastric Cancer Management and Outcomes
- Liver Disease and Transplantation
- Gastrointestinal Tumor Research and Treatment
- Mesenchymal stem cell research
- Tendon Structure and Treatment
- Case Reports on Hematomas
- Appendicitis Diagnosis and Management
- Bacterial Infections and Vaccines
- Viral Infections and Vectors
Second Affiliated Hospital of Zhejiang University
2021-2023
Guiyang Medical University
2023
Weatherford College
2021
Zhejiang University
2009-2021
Tongji University
2013-2021
Shanghai Tenth People's Hospital
2013-2021
81th Hospital of PLA
2017
First Affiliated Hospital Zhejiang University
2013
Sir Run Run Shaw Hospital
2009
Abstract The administration of mesenchymal stem cells/multipotent stromal cells (MSCs) to enhance tissue repair is currently undergoing clinical trials. Some studies, including our previous work, have also revealed the beneficial effect MSCs in severe acute pancreatitis (SAP); however, their mechanisms or mode action remain controversial. In this study, we demonstrated that intravenously (i.v.)-administered human (hMSCs) remarkably promoted recovery from experimental SAP without significant...
Acute pancreatitis (AP) is a common acute abdominal disease, 10-20% of which can evolve into severe AP (SAP) causing significant morbidity and mortality. Bone marrow-derived mesenchymal stem cells (BMSCs) have the potential repairing SAP, but detailed mechanism remains unknown. We demonstrate here that microRNA-9 (miR-9) modified BMSCs (pri-miR-9-BMSCs) significantly reduce pancreatic edema, infiltration, hemorrhage, necrosis, release amylase lipase. Meanwhile, decreased local/systemic...
Abstract Background Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms. However, duodenal GISTs compromise a small and rare subset few studies have focused on them. We evaluated surgical management of patients with treated by pancreaticoduodenectomy (PD) versus local resection (LR) in our institution analyzed postoperative outcomes. Methods This was retrospective review managed from January 2006 to 2012. Clinicopathologic findings disease-free survival (DFS)...
Abstract The lymph node (LN) status is very important for the survival in pancreatic neuroendocrine tumors (PNETs). Therefore, investigation of factors related to LN metastases has a great clinical significance. aim this study was evaluate predictive value preoperative neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR) and possible parameters on nonfunctional PNETs (NF-PNETs). A retrospective review 101 NF-PNET patients following curative resection lymphadenectomy conducted....
Abstract Although acute osteomyelitis is rare in neonates, it might result severe sequelae such as joint destruction and growth failure if not diagnosed treated early. However, few studies have focused on the clinical features treatment of this disease. A retrospective review 17 cases neonatal osteomyelitis, for which patients underwent medical alone or combined with surgery at Children's Hospital Zhejiang University School Medicine between January 2009 September 2016, was conducted. Medical...
Various inflammation-based prognostic scores have been associated with reduced survival in patients nonfunctional pancreatic neuroendocrine tumor (NF-PNET). However, few studies illuminated the relationship between preoperative gamma-glutamyltransferase (GGT) to lymphocyte ratio index (GLRI) and prognosis of NF-PNET. A retrospective review 125 NF-PNET following curative resection was conducted. The cut-off values for scores, including GLRI, were selected using receiver operating...
The present study was performed to assess the prognostic factors with respect patient survival and clinicopathological characteristics for patients who underwent surgery pancreatic neuroendocrine tumors (PNETs). A retrospective review of pathologically diagnosed PNETs at First Affiliated Hospital, Zhejiang University School Medicine (Hangzhou, Zhejiang, China) between September 2002 2013 conducted. findings, overall (OS) rate disease‑free (DFS) were analyzed. Prognostic determined by...