- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- Dementia and Cognitive Impairment Research
- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- Alzheimer's disease research and treatments
- Heart Rate Variability and Autonomic Control
- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Epilepsy research and treatment
- Visual perception and processing mechanisms
- Health, Environment, Cognitive Aging
- Neurological disorders and treatments
- Action Observation and Synchronization
- Advanced MRI Techniques and Applications
- Sleep and Wakefulness Research
- Neonatal and fetal brain pathology
- Motor Control and Adaptation
- Optical Imaging and Spectroscopy Techniques
- Advanced Neuroimaging Techniques and Applications
- Electromagnetic Fields and Biological Effects
- Brain Tumor Detection and Classification
Università degli Studi eCampus
2021-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2016-2025
Universidad de Los Andes
2025
IRCCS Ospedale San Raffaele
2013-2024
Vita-Salute San Raffaele University
2021-2024
San Raffaele University of Rome
2023
Neuroscience Institute
2020
Foundation for Cardiovascular Biomedical Research and Gene and Cell Therapy
2014-2015
Sapienza University of Rome
2003-2014
Restoration of touch after hand amputation is a desirable feature ideal prostheses. Here, we show that texture discrimination can be artificially provided in human subjects by implementing neuromorphic real-time mechano-neuro-transduction (MNT), which emulates to some extent the firing dynamics SA1 cutaneous afferents. The MNT process was used modulate temporal pattern electrical spikes delivered median nerve via percutaneous microstimulation four intact and implanted intrafascicular...
Conscious and unconscious visuospatial processes have been related to parietooccipital cortical activation as revealed by late visual-evoked potentials. Here the working hypothesis was that a specific pattern of pre- poststimulus theta (about 4–6 Hz) alpha 6–12 rhythms is differently represented during conscious compared with processes. Electroencephalographic (EEG) data (128 channels) were recorded in normal adults task. A cue stimulus appeared at right or left (equal probability) monitor...
The aim of this study was to investigate the neuronal network characteristics in physiological and pathological brain aging. A database 378 participants divided three groups analyzed: Alzheimer's disease (AD), mild cognitive impairment (MCI
Abstract Cortical gray matter volume and resting state cortical electroencephalographic rhythms are typically abnormal in subjects with amnesic mild cognitive impairment (MCI) Alzheimer's disease (AD). Here we tested the hypothesis that MCI AD subjects, abnormalities of EEG a functional reflection atrophy across disease. Eyes‐closed data were recorded 57 healthy elderly (Nold), 102 MCI, 108 patients. was indexed by magnetic resonance imaging according to neuroimaging initiative project (...
Modern analysis of electroencephalographic (EEG) rhythms provides information on dynamic brain connectivity. To test the hypothesis that aging processes modulate connectivity network, EEG recording was conducted 113 healthy volunteers. T
Several studies have shown that, in spite of the fact that motor symptoms manifest late course Alzheimer's disease (AD), neuropathological progression cortex parallels other brain areas generally considered more specific targets neurodegenerative process. It has been suggested excitability is enhanced AD from early stages, and this related to disease's severity progression. To investigate neurophysiological hallmarks functionality we combined transcranial magnetic stimulation (TMS) with...
Background. After cerebral ischemia, disruption and subsequent reorganization of functional connections occur both locally remote to the lesion. Recently, complexity brain connectivity has been described using graph theory, a mathematical approach that depicts important properties complex systems by quantifying topologies network representations. Functional dynamic changes can be reliably analyzed via electroencephalography (EEG) recordings even when they are not yet reflected in structural...
In the last decades, several studies showed that wearable sensors, used for assessing Parkinson's disease (PD) motor symptoms and recording their fluctuations, could provide a quantitative reliable tool patient's performance monitoring.The aim of this study is to make step forward capability quantitatively describing PD symptoms. The specific aims are: identify most sensible place where locate sensors monitor bradykinesia rigidity, objective indexes able discriminate OFF/ON status, patients...
Abstract Introduction Dementia in its various forms represents one of the most frightening emergencies for aging population. Cognitive decline—including Alzheimer's disease (AD) dementia—does not develop few days; mechanisms act progressively several years before clinical evidence. Methods A preclinical stage, characterized by measurable cognitive impairment, but overt dementia, is represented mild impairment (MCI), which progresses to—or, more accurately, already a prodromal form of—AD...