A5022330069- Cutaneous Melanoma Detection and Management
- Melanoma and MAPK Pathways
- Nonmelanoma Skin Cancer Studies
- RNA regulation and disease
- Genetic and rare skin diseases.
- melanin and skin pigmentation
- Autoimmune Bullous Skin Diseases
- Cancer and Skin Lesions
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Acne and Rosacea Treatments and Effects
- Sympathectomy and Hyperhidrosis Treatments
- Hidradenitis Suppurativa and Treatments
- Infectious Diseases and Mycology
- Nerve injury and regeneration
- Psoriasis: Treatment and Pathogenesis
- Quinazolinone synthesis and applications
- Dermatological and Skeletal Disorders
- Synthesis of Tetrazole Derivatives
- Food Allergy and Anaphylaxis Research
- Dermatologic Treatments and Research
- Virus-based gene therapy research
- Virology and Viral Diseases
- Neurofibromatosis and Schwannoma Cases
- Cell Adhesion Molecules Research
Universitätsmedizin Göttingen
2017-2023
University of Göttingen
2015-2023
Zero to Three
2020-2021
University Medical Center
2021
TU Dresden
2012
Max Planck Institute of Molecular Cell Biology and Genetics
2005
Currently, there are no effective drug therapy options that lead to the regression of rhinophyma. Many surgical procedures for treating rhinophyma have been published; however, limited data on their effectiveness. In addition, these treatment often persistent hypopigmented scarring if excessive ablation or heat is applied. To prevent excessively deep and enable precise nasal contouring, a combination was developed, integrating classic rhinoshave coarse followed by laser fine contouring....
Foamy virus (FV) vector systems have recently demonstrated their power as efficient gene transfer tools for different target tissues. Unfortunately, FVs cannot be naturally pseudotyped by heterologous viral glycoproteins due to an unusual particle morphogenesis involving a FV Env-dependent release process. Therefore, current are constrained the broad host cell range provided cognate glycoprotein. We evaluated approaches pseudotyping of vectors, in which specific Gag–Env interaction,...
Melanocytic nevi in lymph nodes (NNs) are an important histological differential diagnosis of initial sentinel node (SN) metastasis melanoma. Our aim was to associate NN SNs with clinicopathologic features and survival rates 1, 250 patients SN biopsy for melanoma.To compare present absent NN, we used Fisher's exact test, Mann-Whitney U multivariate logistic regression models this retrospective observational study based on a prospectively maintained institutional database.NN prevalence...
We saw a 47-year-old German female with progressive disseminated hyperpigmentation that had commenced in childhood.Her mother, grandmother und maternal uncle were likewise affected.She been diagnosed basal cell carcinomas on the right shoulder and umbilical region 2007 2013, respectively; actinic keratoses her cheeks beneath left eye 2016.Furthermore, she suffered from depression, fibromyalgia colitis ulcerosa, latter being treated Vedolizumab since March 2017.
Immunotherapies using checkpoint blockade and BRAF/MEK therapies have improved overall survival (OS) in patients with unresectable melanoma metastases. In this retrospective study, we aimed to demonstrate the resulting increase melanoma-specific (MSS) OS after excision of primary melanomas (≥1 mm thick) sentinel lymph node (SN) biopsy (SNB). Using Kaplan-Meier estimates Cox models, compared two consecutive cohorts. Patients cohort 1 (N = 518) underwent SNB between 1998 2009, 2 460) 2010...
AnamneseEin 52-jähriger deutscher Mann stellte sich mit einer Verhornungsstörung an Händen und Füßen in unserer Ambulanz vor.Sein Vater seine Schwester waren ebenfalls betroffen.Die Hautveränderungen hatten kurz nach der Geburt ausgebildet
Keiner.
Abstract Purpose: Melanocytic nevi in lymph nodes (NNs) are an important histological differential diagnosis of initial sentinel node (SN) metastasis melanoma. Our aim was to associate NN SNs with clinicopathologic features and survival rates 1 250 patients SN biopsy for Methods: To compare present absent NN, we used Fisher's exact test, Mann-Whitney U multivariate logistic regression models this retrospective observational study based on a prospectively maintained institutional database....