A5074105062- Acute Kidney Injury Research
- COVID-19 Clinical Research Studies
- Chronic Kidney Disease and Diabetes
- Muscle and Compartmental Disorders
- Immunotherapy and Immune Responses
- Dialysis and Renal Disease Management
- Climate Change and Health Impacts
- Immune Cell Function and Interaction
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- T-cell and B-cell Immunology
- Electrolyte and hormonal disorders
- Renal function and acid-base balance
- Skin Diseases and Diabetes
- Drug-Induced Adverse Reactions
- Contact Dermatitis and Allergies
- SARS-CoV-2 and COVID-19 Research
- Artificial Intelligence in Healthcare and Education
- Cell Adhesion Molecules Research
- Machine Learning in Healthcare
- Potassium and Related Disorders
- COVID-19 Impact on Reproduction
- Autopsy Techniques and Outcomes
- Blood disorders and treatments
Charité - Universitätsmedizin Berlin
2020-2024
Humboldt-Universität zu Berlin
2021-2024
Freie Universität Berlin
2021-2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2024
University Hospital of Zurich
2022
University of Göttingen
2015-2017
Abstract Background Acute kidney injury (AKI) occurs frequently in critically ill patients and is associated with adverse outcomes. Cellular mechanisms underlying AKI cell responses to remain incompletely understood. Methods We performed single-nuclei transcriptomics, bulk molecular imaging studies, conventional histology on tissues from 8 individuals severe (stage 2 or 3 according Kidney Disease: Improving Global Outcomes (KDIGO) criteria). Specimens were obtained within 1–2 h after had...
IntroductionAcute kidney injury (AKI) is an important complication in COVID-19, but its precise etiology has not fully been elucidated. Insights into AKI mechanisms may be provided by analyzing the temporal associations of clinical parameters reflecting disease processes and development.MethodsWe performed observational cohort study 223 consecutive COVID-19 patients treated at 3 sites a tertiary care referral center to describe evolvement severe (Kidney Disease: Improving Global Outcomes...
Abstract The COVID-19 pandemic has posed a major challenge to healthcare systems globally. Millions of people have been infected, and millions deaths reported worldwide. Glucocorticoids attracted worldwide attention for their potential efficacy in the treatment COVID-19. Various glucocorticoids with different dosages durations studied patients severities, suitable dosage duration not yet defined. This study aimed investigate whether in-hospital survival differs between critically ill treated...
ABSTRACT Background Hypernatremia presents a common complication in intensive care unit (ICU) patients, associated with increased mortality and length of stay. This study investigates the effect sodium chloride 0.9% compared glucose 5% solution as standard intravenous drug diluent on prevalence hypernatremia medical ICU. Methods is retrospective before-and-after comparing two consecutive patient groups before after solvent was changed from to for compatible medications. A total 265 adult...
Abstract Background The COVID-19 pandemic has posed a major challenge to healthcare systems globally. Millions of people have been infected, and millions deaths reported worldwide. Glucocorticoids attracted worldwide attention for their potential efficacy in the treatment COVID-19. Various glucocorticoids with different dosages durations studied patients severities, suitable dosage duration not yet defined. This study aimed investigate whether in-hospital survival differs between critically...
Abstract Background Acute kidney injury (AKI) occurs frequently in critically ill patients and is associated with adverse outcomes. Cellular mechanisms underlying AKI cell responses to remain incompletely understood. Methods We performed single-nuclei transcriptomics, bulk molecular imaging studies, conventional histology on tissues from 8 individuals severe (stage 2 or 3 according Kidney Disease: Improving Global Outcomes (KDIGO) criteria). Specimens were obtained within 1-2 hours after had...
The use of levamisole as the most frequent adulterant cocaine has merged in previously unknown toxicities, notably a disease entity called cocaine/levamisole-associated autoimmune syndrome (CLAAS). Clinically, CLAAS can manifest with diverse cutaneous and extracutaneous features sharing common laboratory findings (neutropenia, autoantibody patterns). We report case cocaine-abusing female patient relapsing episodes painful ulcers, worsening expanding over three-year period. exhibited all...
Background: The COVID-19 pandemic has had a profound impact on health, everyday life and economics around the world. An important complication that can arise in connection with infection is acute kidney injury. A recent observational cohort study of patients treated at multiple sites tertiary care center Berlin, Germany identified risk factors for development (severe) Since inferring results from single be tricky, we validate these findings potentially adjust by including external...