A5011524285- Reproductive Biology and Fertility
- Photoreceptor and optogenetics research
- Sperm and Testicular Function
- Marine and coastal plant biology
- Microtubule and mitosis dynamics
- Neurobiology and Insect Physiology Research
- Neuroscience and Neuropharmacology Research
- Marine Biology and Environmental Chemistry
- Plant Molecular Biology Research
- Cellular transport and secretion
- Cellular Mechanics and Interactions
- Ion channel regulation and function
- Circadian rhythm and melatonin
- Nerve injury and regeneration
- Reproductive biology and impacts on aquatic species
- Ion Channels and Receptors
- Neurogenesis and neuroplasticity mechanisms
- S100 Proteins and Annexins
- Mitochondrial Function and Pathology
- Planarian Biology and Electrostimulation
- Developmental Biology and Gene Regulation
- Alzheimer's disease research and treatments
- Signaling Pathways in Disease
- Cephalopods and Marine Biology
- Echinoderm biology and ecology
Stazione Zoologica Anton Dohrn
2014-2024
Seoul National University
2015
GTx (United States)
2007
University of Southern California
1999-2003
Children's Hospital of Los Angeles
1999
University of Pittsburgh Medical Center
1997
University of Pittsburgh
1995
When preparing for fertilization, oocytes undergo meiotic maturation during which structural changes occur in the endoplasmic reticulum (ER) that lead to a more efficient calcium response. During and subsequent actin cytoskeleton also undergoes dramatic restructuring. We have recently observed rearrangements of induced by actin-depolymerizing agents, or actin-binding proteins, strongly modulate intracellular (Ca2+) signals process. However, significance dynamic F-actin within fertilized egg...
Scope: Milk from various species differs in nutrient composition. In particular, human milk (HM) and donkey (DM) are characterised by a relative high level of triacylglycerol enriched palmitic acid sn-2 position. These dietary fats seem to exert beneficial nutritional properties through N-acylethanolamine tissue modulation. The aim this study is compare the effects cow (CM), DM, HM on inflammation glucose lipid metabolism, focusing mitochondrial function, efficiency dynamics skeletal muscle,...
Previous data have suggested that the large nerve terminals present in synaptosomal fraction from squid optic lobe are capable of protein synthesis (Crispino et al., 1993a,b). We further examined this issue by comparing translation products and microsomal polysomes. Both preparations programmed an active process translation, which was completely abolished their previous treatment with EDTA. After immunoabsorption newly synthesized neurofilament (NF) proteins, labeling ratio 60 70 kDa NF...
Ionomycin is a Ca2+-selective ionophore that widely used to increase intracellular Ca2+ levels in cell biology laboratories. It also occasionally activate eggs the clinics practicing vitro fertilization. However, neither precise molecular action of ionomycin nor its secondary effects on eggs' structure and function well known. In this communication we have studied starfish oocytes zygotes. By use confocal microscopy, calcium imaging, as light transmission electron demonstrated immature...
Background Fertilization of echinoderm eggs is accompanied by dynamic changes the actin cytoskeleton and a drastic increase cytosolic Ca2+. Since plasma membrane-enriched phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) serves as precursor inositol 1,4,5 trisphosphate (InsP3) also regulates actin-binding proteins, PIP2 might be involved in these two processes. Methodology/Principal Findings In this report, we have studied roles at fertilization starfish using fluorescently tagged...
Fertilization and early development are usually the most vulnerable stages in life of marine animals, biological processes during this period highly sensitive to environment. In nature, sea urchin gametes shed seawater, where they undergo external fertilization embryonic development. a laboratory, it is possible follow exact morphological biochemical changes taking place fertilized eggs developing embryos. Thus, observation successful subsequent can be used as convenient biosensor assess...
During sea urchins fertilization, the activating spermatozoon triggers a series of physiological changes that transforms quiescent egg into dynamic zygote. It has been suggested several these activation events, e.g. sperm-induced plasma membrane depolarization and Ca2+-linked cortical reaction, play additional roles to prevent entry supernumerary spermatozoa. In particular, abrupt shift in potential at which is sustained by Na+ influx, considered as fast mechanism block polyspermy. To test...