A5070470113- Probiotics and Fermented Foods
- Drug Solubulity and Delivery Systems
- Gut microbiota and health
- Microencapsulation and Drying Processes
- Advanced Drug Delivery Systems
- Folate and B Vitamins Research
- Advancements in Transdermal Drug Delivery
- Wastewater Treatment and Nitrogen Removal
- Infant Health and Development
- Membrane Separation Technologies
- Iron Metabolism and Disorders
- Metabolism and Genetic Disorders
- Oral microbiology and periodontitis research
- biodegradable polymer synthesis and properties
- Trace Elements in Health
- Proteins in Food Systems
- Protein purification and stability
- Nanoparticle-Based Drug Delivery
- Ocular Surface and Contact Lens
- Powder Metallurgy Techniques and Materials
- Essential Oils and Antimicrobial Activity
- Microbial Fuel Cells and Bioremediation
- Water Quality Monitoring Technologies
- Polymer Foaming and Composites
- Pickering emulsions and particle stabilization
University of Antwerp
2015-2024
Ghent University
1997-2019
Metropolitan University
2019
American Pharmacists Association
2015
Janssen (Belgium)
2004
Summary A number of clinical studies have shown protective effects lactobacilli against Candida species in the gastrointestinal tract, urogenital tract and oral cavity, while others did not show clear effects. Evidence on mode action is also still lacking. In this study, anti‐ activity model probiotic strain Lactobacillus rhamnosus GG was explored different assays to determine molecular interactions. We found that L. able interfere with growth, morphogenesis adhesion. These three aspects 's...
Tailored skin microbiome modulation approaches with probiotics are highly challenging. Here, we show that lactobacilli underestimated members of the microbiota. We select specific strains nomadic for their functional applicability on and capacity to inhibit growth inflammation by pathobionts. The formulated as microcapsules topical formulations tested in patients mild-to-moderate acne. selected able reduce inflammatory lesions a pilot placebo-controlled study. Daily application 8 weeks is...
Mixed hemi/ad-micelle sodium dodecyl sulfate (SDS)-coated magnetic iron oxide nanoparticles (MHAMS-MIONPs) were used as an efficient adsorbent for both removal and preconcentration of two important carcinogenic xanthine dyes named rhodamine-B (RB) rhodamine-6G (RG). To gain insight in the configuration SDS molecules on surface MIONPs, zeta potential measurements performed different [SDS]/[MIONP] ratios. Zeta data indicated that mixed MHAM was formed ratios over range 1.1 to 7.3. Parameters...
Abstract Vulvovaginal candidosis (VVC) is a common condition with severe symptoms and high recurrence rates. Probiotic lactobacilli are explored as alternatives to azole treatments. Although the vaginal microbiota generally not depleted in during VVC, studies indicate that functionality antimicrobial activity of impaired. We selected three strains from Lactobacillus genus complex ( L. rhamnosus GG, pentosus KCA1 plantarum WCFS1) based on vitro evaluation formulated them gel for application....
The preservation of the viability microorganisms in probiotic formulations is most important parameter ensuring adequate concentration live at time administration. formulation and processing techniques used to produce these can influence microbial viability. However, it also required that bacteria maintain their key capacities during processing, shelf life. In this study, we investigated impact spray-drying on different cell wall properties model strain Lactobacillus rhamnosus GG, including...
During spray drying, probiotics encounter several stresses which can reduce their viability. To obtain powder with a sufficient amount of viable probiotics, we evaluated the effects different process parameters, such as initial cell concentration and bacterial growth phase, on viability model probiotic Lactobacillus rhamnosus GG. Increasing biomass did not positively impact after drying. For growth, found that stationary grown cells were more resistant to spray-drying than mid-log cells,...
Summary The skin is home to an important part of our commensal microbiota, despite it being a cool, acidic and desiccated environment. Tailored microbiome modulation approaches with, for example probiotics, are highly challenging this body site. Here we show by next-generating sequencing that Lactobacillus taxa -especially those known be dominant in the human vagina- underestimated members microbiota. Specific strains were selected lab formulated viable form oil water-based topical cream....
Abstract Cecropia species are traditionally used in Latin American folk medicine and available as food supplements with little information warranting their quality. The optimum conditions for the extraction of chlorogenic acid (CA), total flavonoids (TF) flavonolignans (FL) from leaves were determined using a fractional factorial design (FFD) central composite (CCD). A reversed-phase high-performance liquid chromatographic method coupled to diode array detector (HPLC-DAD) was validated...
Abstract Dry eye syndrome (DES), a multifactorial disorder which leads to ocular discomfort, visual disturbance and tear film instability, has rising prevalence limited treatment options. In this study, newly developed trypsin-like serine protease inhibitor (UAMC-00050) in drop formulation was evaluated treat inflammation. A surgical animal model of dry employed investigate the potential UAMC-00050 on pathology. Animals treated with displayed significant reduction surface damage after...
A laboratory-scale sequencing batch reactor (SBR) was operated for 450 days to assess aerobic granule formation when treating brewery/bottling plant wastewater by consistent application of a feast/famine regime. The experiment divided into three major periods according the different operational conditions: (I) no pH control and strong fluctuations in organic loading rate (OLR) (1.18 ± 0.25 kgCOD·(m3·day)-1), (II) aeration strategy reduce OLR (1.45 0.65 kgCOD·(m3·day)-1) (III) stable (1.42...