A5048994832- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Infections and bacterial resistance
- Eosinophilic Esophagitis
- Mycobacterium research and diagnosis
- Helicobacter pylori-related gastroenterology studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Diphtheria, Corynebacterium, and Tetanus
- Acute Ischemic Stroke Management
- Biosensors and Analytical Detection
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial biofilms and quorum sensing
- Viral gastroenteritis research and epidemiology
- Pneumonia and Respiratory Infections
- Enterobacteriaceae and Cronobacter Research
- Vibrio bacteria research studies
- Blood Coagulation and Thrombosis Mechanisms
- Bacterial Infections and Vaccines
- Antibiotics Pharmacokinetics and Efficacy
Nara Medical University
2016-2022
Tohoku University
2015-2016
Kawagoe Technical High School
2016
Kyorin University
2012
Stenotrophomonas maltophilia is an important pathogen in healthcare-associated infections. S. may contain Smqnr, a quinolone resistance gene encoding the pentapeptide repeat protein, which confers low-level upon expression heterologous host. We investigated prevalence of Smqnr and plasmid-mediated (PMQR) determinants isolates from Japan. A total 181 consecutive nonduplicate clinical were collected four areas The antimicrobial susceptibility profiles for these strains determined. PCR was...
Nontypeable Haemophilus influenzae is a particularly important cause of acute otitis media (AOM). There high prevalence β-lactamase-nonproducing ampicillin-resistant (BLNAR) strains in Japanese children, which associated with recurrent AOM and prolonged treatment. The aim this study was to investigate the antimicrobial susceptibility profile, mechanisms ampicillin resistance molecular epidemiology H. causing children.One hundred fifty-seven isolated from middle ear fluid pediatric patients...
Carbapenemase-producing Enterobacterales (CPE) pose one of the most serious antimicrobial resistance threats to public health worldwide. The outcome CPE infection differs depending on mechanism. Therefore, rapid detection is essential for optimizing patient management. carbapenem inactivation method (CIM) and modified CIM (mCIM) are standard methods detecting CPE, but they usually require 24 h generate results. Recently, an immunochromatographic assay, NG-Test CARBA 5, has become...
We investigated the effect of clot activators carried over from serum tube on major coagulation tests during phlebotomy. First, blood specimens 30 normal subjects were mixed with small amounts fluid containing activators, and their effects various determined. Only value fibrin monomer complex displayed a remarkable change when thrombin-containing was added to specimens. Subsequently, 100 paired (taken 75 healthy volunteers 25 patients taking warfarin) collected in tubes before after using...
Mutations in the quinolone resistance-determining regions (QRDRs) of Acinetobacter baumannii DNA gyrase (gyrA) and topoisomerase IV (parC) are linked to fluoroquinolone (FQ) resistance. We developed a mismatched PCR-restriction fragment length polymorphism (RFLP) assay detect mutations gyrA parC QRDRs associated with FQ resistance A. baumannii.Based on conserved sequences baumanniigyrA parC, two primer sets were designed for PCR-RFLP (codons 83 87) 80 84) by introducing an artificial...
Although the prevalence of carbapenem-resistant Enterobacterales remains low in Japan, these bacteria are a growing problem worldwide, owing to their multidrug resistance phenotype. We isolated multidrug-resistant Providencia rettgeri strain, NR1418, harboring rare blaIMP variant, blaIMP-70, novel blaCTX-M designated blaCTX-M-253, and blaMOX-1. This strain is resistant β-lactams, amikacin, levofloxacin, colistin. Genomic analysis revealed that NR1418 carries two plasmids, pNR1418-1...