A5065204464- Helicobacter pylori-related gastroenterology studies
- Cancer Genomics and Diagnostics
- Diabetes Management and Research
- Global Health and Surgery
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Gastroesophageal reflux and treatments
- Health Services Management and Policy
- Gastrointestinal motility and disorders
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Acute Kidney Injury Research
- Diabetes and associated disorders
- Pharmacovigilance and Adverse Drug Reactions
- Health and Conflict Studies
- Cancer-related Molecular Pathways
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Blood donation and transfusion practices
- Esophageal Cancer Research and Treatment
- Liver Disease Diagnosis and Treatment
- Amoebic Infections and Treatments
University of Rwanda
2015-2024
Centre Hospitalier Universitaire de Kigali
2015-2024
University of Kigali
2020-2024
Dartmouth–Hitchcock Medical Center
2017
Harvard University
2016
Boston Children's Hospital
2016
Background The Rwanda Human Resources for Health Program (HRH Program) is a 7-year (2012-2019) health professional training initiative led by the Government of with goals large, diverse, and competent workforce strengthening capacity academic institutions in Rwanda. Methods data this organizational case study was collected through official reports from Ministry (MoH) 22 participating US institutions, databases MoH College Medicine Sciences (CMHS) Rwanda, surveys completed co-authors. Results...
Successful H. pylori treatment requires the knowledge of local antimicrobial resistance. Data on efficacy eradication regimens available in sub-Saharan Africa are scant, hence optimal is unknown. Our goals were to determine Rwanda as well evaluate effect health-related quality life (HRQoL) patients undergoing esophagogastroduodenoscopy. This a randomized controlled trial conducted from November 2015 October 2016 at tertiary hospital Rwanda. Enrollees 299 (35% male, age 42 ± 16 years (mean...
Lack of access to health and medical education resources for doctors in the developing world is a serious global problem. In Rwanda, with population 11 million, there only one school, hence shortage well-trained staff. The growth interactive technologies has played role improvement care developed countries offered alternative ways offer continuous while improving patient's care. However, low middle-income (LMIC) like Rwanda have struggled implement adapted local settings practice continuing...
Abstract Background Gastric cancer is the sixth most frequently diagnosed and third in causing cancer-related death globally. The mutated gene human cancers TP53 , which plays a pivotal role initiation progression. In Africa, particularly Rwanda, data on mutations are lacking. Therefore, this study intended to obtain mutation status Rwandan patients with gastric cancer. Results Formalin-fixed paraffin-embedded tissue blocks of 95 histopathologically proven carcinoma were obtained from...
IntroductionAcute kidney injury (AKI) is prevalent in low- and middle-income countries (LMIC) associated with significant morbidity mortality, particularly among hospitalized patients. Successful strategies for the prevention management of AKI these are dependent on capacity primary care centers to provide optimal initial patients at risk this disorder.MethodsFrom December 2018 February 2019, using mixed methods, we assessed hospital knowledge clinicians relevant prevention, diagnosis,...
Acute kidney injury (AKI) requiring renal replacement therapy is associated with high mortality. The study assessed the impact of introduction hemodialysis (HD) on outcomes patients AKI in Rwanda.A single center retrospective that evaluated clinical profile and survival HD [AKI-D] at a tertiary hospital Rwanda. Data was collected who received for from September 2014 to December 2016. Patient demographics, comorbidities, presentation, laboratory tests, mortality were reviewed analyzed....
This paper presents a mathematical model of glucose-insulin dynamics which is specific for type 2 diabetic patients. The general modelling obtained by simplification global compartmental John Thomas Sorensen. parameters are estimated using nonlinear optimization and data collected in Rwanda In order to identify evaluate possible abnormalities patients, the Sampling Importance Resampling (SIR) particle filtering algorithm used implemented through discretization developed model. process done...
Strongyloides stercoralis is one of the most neglected tropical diseases. Sparse, dated central African and Rwandan data on seroprevalence are available to guide public health efforts clinical care. In February 2016 we conducted a community-based cross-sectional study among 539 asymptomatic participants in rural area Gisagara District, Southern Province, Rwanda. Direct faecal smear (DFS) modified Koga agar plate culture (APC) were used detect S. infection single stool sample. Data other...
Objectives We aimed to develop and validate Kinyarwanda versions of Short-Form Leeds Dyspepsia Questionnaire (SF-LDQ) Nepean Index (SF-NDI) measure the frequency severity dyspepsia associated quality-of-life impact in Rwanda. Setting A single, tertiary care centre Participants 200 consecutive Kinyarwanda-speaking patients referred endoscopy (100 patients) or medical outpatients patients). Interventions SF-LDQ SF-NDI were developed from English by translation, with back crosschecking pilot...
Background Leptospirosis is a zoonotic disease transmitted through the urine of wild and domestic animals, responsible for over 50,000 deaths each year. In East Africa, prevalence varies greatly, from as low 7% in Kenya to 37% Somalia. Transmission epidemiology also around world, with research Nicaragua showing that rodents are most clinically important, while studies Egypt Chile suggest dogs may play more important role. There no published leptospirosis Rwanda. Methods & findings We...
Abstract Background Peritoneal tuberculosis is the most common cause of low albumin gradient ascites in developing countries, but it can be easily confused with other causes ascites. requires early recognition symptoms and signs order to make a quick diagnosis for appropriate treatment . Measurement adenosine deaminase (ADA) level > 39 fluid an established test diagnose peritoneal tuberculosis. Many low-income countries do not currently fluid, including Rwanda. Method Cross-sectional,...
Mathematical modelling of glucose-insulin system is very important in medicine as a necessary tool to understand the homeostatic control human body. It can also be used design clinical trials and evaluation diabetes prevention. In last three decades so much work has been done this direction. One most notable models global six compartment-mathematical model with 22 ordinary differential equations due John Thomas Sorensen. This paper proposes more simplified only 6 by introducing tissue...
Introduction Dyspepsia accounts for a significant burden of worldwide disease, but there is relative paucity data from the sub-Saharan African setting. We undertook to describe burden, risk factors and severity dyspepsia across Rwanda. Methods performed population-based clustered cross-sectional survey between November 2015 January 2016, nationwide in Rwanda, using Short Form Leeds Questionnaire presence dyspepsia, Nepean Index concomitant quality life effects. Univariate multivariate...
INTRODUCTION: Upper gastrointestinal (GI) bleeding is a common emergency that results in significant morbidity and mortality. In Rwanda, data on causes outcomes are lacking. The aim of this study was to identify the upper patients referred tertiary referral centers.
 METHODS: This an observational prospective for which we enrolled all who presented with presumed underwent endoscopy. We studied during 3 months follow-up after initial presentation from February 2019 September 2019.
...
Mutations in the TP53 tumor suppressor gene are well-established drivers of colorectal cancer (CRC) development. However, data on prevalence variants and their association with consensus molecular subtype (CMS) classification patients CRC from Rwanda currently lacking. This study addressed this knowledge gap by investigating mutation status concerning CMS a cohort Rwanda. Formalin-fixed paraffin-embedded (FFPE) tissue blocks were obtained 51 at University Teaching Hospital Kigali, Exons 4 to...
Abstract Background Commercial single-use endoscopic multiband ligators, used for esophageal variceal band ligation (EVL), are prohibitively expensive. To enable greater access to EVL, we disruptive innovation develop a novel ligator. Methods We designed and tested prototype handle ‘ENDOhandle’ using computer-aided design modeling exported cap, trigger cord latex form functional banding unit. Results The cost of the unit was US$4.80 compared with several hundred US dollars commercially...
Welcome to Annals of Global Health,Annals Health is a peer-reviewed, fully open access, online journal dedicated publishing high quality articles all aspects global health. The journal's mission advance health, promote research, and foster the prevention treatment disease worldwide. Its goals are improve health well-being people, equity, wise stewardship earth's environment. latest impact factor 3.64.Annals supported by Program for Public Common Good at Boston College. It was founded in 1934...