Lamia Benguedouar

ORCID: 0000-0002-6161-6445
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About
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Research Areas
  • Bee Products Chemical Analysis
  • Essential Oils and Antimicrobial Activity
  • Nuts composition and effects
  • Phytochemistry and Biological Activities
  • Plant chemical constituents analysis
  • Garlic and Onion Studies
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Plant-Derived Bioactive Compounds
  • Sunflower and Safflower Cultivation
  • Microbial Inactivation Methods
  • Toxin Mechanisms and Immunotoxins
  • Sesquiterpenes and Asteraceae Studies
  • Chronic Kidney Disease and Diabetes
  • Biological and pharmacological studies of plants
  • Chemotherapy-induced organ toxicity mitigation
  • Bioactive Compounds in Plants
  • Acute Kidney Injury Research
  • Natural Compound Pharmacology Studies
  • Skin Protection and Aging
  • Synthesis and bioactivity of alkaloids
  • Natural product bioactivities and synthesis
  • Phytochemical compounds biological activities
  • Cancer Treatment and Pharmacology
  • Phytochemistry Medicinal Plant Applications

University of Jijel
2008-2025

Centre Hospitalier Universitaire de Reims
2015

Université de Reims Champagne-Ardenne
2015

Melanoma is the more dangerous skin cancer, and metastatic melanoma still carries poor prognosis. Despite recent therapeutic advances, prolonged survival remains rare research required. Propolis extracts from many countries have attracted a great deal of attention for their biological properties. We here investigated ability an ethanolic extract Algerian propolis (EEP) to control tumour growth when given mice bearing B16F1melanoma either as preventive or treatment. EEP after occurrence...

10.2174/1871520616666160211124459 article EN Anti-Cancer Agents in Medicinal Chemistry 2016-08-15

The purpose of our study was to divulge the antiproliferative effect an ethanolic extract Algerian propolis (EEP) in human lung adenocarcinoma cell line (A549) and reveal chemopreventive role against benzo(a)pyrene-induced carcinogenesis albino Wistar rats. Cytotoxicity EEP evaluated using MTT assay adhesion A549 cells. Moreover, rats were given 25 mg/kg for 5 days before induction experimental cancer by a single intraperitoneal dose 200 benzo(a)pyrene. Body weight, lipid peroxidation,...

10.1590/s2175-97902018000117396 article EN cc-by Brazilian Journal of Pharmaceutical Sciences 2018-06-07

This study evaluates the antioxidant effects of aqueous leaf extract Pistacia lentiscus (ALEPL) and its potential to counteract oxaliplatin (OXA)-induced mitochondrial oxidative stress in rat livers, a common side effect chemotherapy cancer treatment. Bioactive compounds were identified using High-Performance Liquid Chromatography coupled with Tandem Mass Spectrometry (HPLC-MS MS), Fourier-Transform Infrared Spectroscopy (FTIR) Atomic Absorption Spectrophotometry (AAS) for chemical mineral...

10.1080/01480545.2024.2429615 article EN Drug and Chemical Toxicology 2024-11-27

Ferulenol, a sesquiterpene coumarin, was extracted from "Ferula vesceritensis" and possesses pro-oxidative anticancer effects in different types of cancer.The objective this study is to determine whether ferulenol has an effect by regulation the Bcl2 protein expression lung cancer induced benzo[a]pyrene Wistar rats.Rats group 1 have received, intraperitoneally, olive oil considered as controls, animals 2 were treated with 100 mg/kg intraperitoneally order induce for 24 weeks, 3rd groups rats...

10.2174/1871520617666170213143444 article EN Anti-Cancer Agents in Medicinal Chemistry 2017-02-23

Pharmacognosy Magazine,2018,14,56,333-337.DOI:10.4103/pm.pm_611_17Published:August 2018Type:Original ArticleAuthors:Malika Boulmeltout, Amar Zellagui, Lamia Benguedouar, and Gillian Barratt3 Mesbah Lahouel Author(s) affiliations:Malika Boulmeltout1, Zellagui2, Benguedouar1, Barratt3, Lahouel1 1 Department of Natural Life Sciences, Laboratory Molecular Toxicology, Faculty University Jijel, Algeria 2 Biomolecules Plant Breeding, Sciences SNV, Larbi Ben Mhidi, Oum El Bouaghi, 3 CNRS, Pharmacy,...

10.4103/pm.pm_611_17 article EN Pharmacognosy Magazine 2018-01-01

Abstract Thirteen compounds (flavonoids, phenolic acids and sterols) were isolated from the aerial parts of Hypericum tomentosum L. Their structures established on basis physical spectroscopic analysis, by comparison with literature data. In vivo in vitro protective effect butanolic extract H. (BEHT) against acute oxidative stress induced a single dose 20 mg/kg epirubicin (an anticancer drug) was evaluated female Wistar rat using kidney heart cytosolic fraction. Scavenging BEHT, lipid...

10.1080/22311866.2012.10719123 article EN Journal of Biologically Active Products from Nature 2012-01-01
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