A5020519228- Surface Treatment and Residual Stress
- Infrared Target Detection Methodologies
- Magnesium Alloys: Properties and Applications
- Metal Alloys Wear and Properties
- Metal and Thin Film Mechanics
- High Entropy Alloys Studies
- Bone Tissue Engineering Materials
- Erosion and Abrasive Machining
- Advanced Measurement and Detection Methods
- Surface Treatment and Coatings
- Aluminum Alloys Composites Properties
- Electromagnetic Effects on Materials
- CCD and CMOS Imaging Sensors
- Autism Spectrum Disorder Research
- Eating Disorders and Behaviors
- Additive Manufacturing Materials and Processes
- Material Properties and Applications
- Advanced Cellulose Research Studies
- Analytical Chemistry and Sensors
- Obsessive-Compulsive Spectrum Disorders
- Modular Robots and Swarm Intelligence
- Job Satisfaction and Organizational Behavior
- Chromatography in Natural Products
- Evacuation and Crowd Dynamics
- Industrial Vision Systems and Defect Detection
Tianjin First Center Hospital
2023-2025
Tianjin Medical University
2023-2025
Emilio Aguinaldo College
2023-2024
Clinical Trial Investigators
2024
Emerald Coast Science Center
2024
Nankai University
2023
University of Akron
2016-2022
Yinchuan First People's Hospital
2022
Northwest A&F University
2022
Tianjin University of Science and Technology
2012-2022
<title>Abstract</title> <bold>Background</bold> The brain age gap (BAG), a neuroimaging-derived biomarker of accelerated aging, faces translational challenges due to model inaccuracies and unclear disease-mechanism linkages. We systematically evaluated BAG's clinical relevance across neuropsychiatric disorders, cognitive trajectories, mortality, lifestyle interventions. <bold>Methods</bold> Using multi-cohort data (UK Biobank [n = 38,967], Alzheimer’s Disease Neuroimaging Initiative [ADNI; n...
Background: Depletion of B cells has resulted in major therapeutic benefits hematological malignancies. Several FDA-approved cell-depleting therapies are available, including CAR-T and T cell engagers (TCE). Blinatumomab, the only CD19-targeting bispecific engager approved for malignancies, disadvantages clinical setting sub-optimal pharmacokinetics, neurotoxicity, CRS, lack long-term efficacy. In this study we present CC312, a trispecific antibody engineered better efficacy by leveraging...
Abstract Background: B cell depletion therapy (BCDT), such as monoclonal antibodies, bispecific T engagers(TCE) and CAR-T,has an extensive history of effectively treating malignancies. Certain BCDT antibodies,e.g. rituximab,are also approved to treat autoimmune diseases(ADs), however demonstrate poor cells in deep tissue which may limit the long-term disease control or remission patients. Recently, anti-CD19 CAR-T, through thorough “resetting” populations, have achieved multi-year drug-free...
Abstract Background Glycemic variability (GV) is increasingly recognised as a critical determinant of outcomes in critically ill patients. However, standardised criteria for assessing GV remain undefined. Objective This study aimed to evaluate the relationship between Mean Amplitude Excursion (MAGE) and mortality intensive care unit (ICU) patients, determine optimal MAGE thresholds distinct patient populations. Methods A retrospective cohort 13 852 adults with ICU stays exceeding 24 h was...
College teachers are producers of scientific knowledge, and innovative behavior is important to this group, especially since overqualification a common phenomenon. However, there much debate about the effect on innovation behavior. Therefore, we used statistical analysis software explore interaction mechanisms between college teachers' using data from 368 questionnaires. Overqualification was found be negatively related behavior, job crafting played mediating role in relationship. Further,...
Abstract Nickel–titanium (NiTi) alloy is an attractive material for biomedical implant applications. In this study, the effects of laser shock peening (LSP) on biocompatibility, corrosion resistance, ion release rate and hardness NiTi were characterized. The cell culture study indicated that LSP‐treated samples had lower cytotoxicity higher survival than untreated samples. Specifically, increased from 88 ± 1.3% to 93 1.1% due LSP treatment. treatment was shown significantly decrease initial...
Herein, an innovative surface severe plastic deformation method, laser‐assisted ultrasonic nanocrystal modification (LA‐UNSM), is used to treat 300M ultra‐high‐strength steel. The results show that the synergistic effect of laser heating and striking in a thicker layer steel compared with UNSM treatment alone. Moreover, depth gradually increases as power level increased. At 68 W, greatest thickness (≈53.6 μm) observed, which 1.7 times UNSM‐treated samples. In addition, forms dense oxide...