Myocardial ischemia/reperfusion injury (MIRI) is a pathophysiological process connected to the onset of numerous heart disorders.The pathogenesis MIRI complex, and it mainly involves calcium overload, classic oxidative stress, mitochondrial disorder, inflammation, microvascular cell death.The clinical treatment options for are presently constrained, making imperative develop new modalities.Recent studies have demonstrated that ferroptosis main cause MIRI.Ferroptosis type regulated...

Abstract The impacts of spatial and temporal variations snowmelt recharge on subsurface flow in a small mountainous watershed were investigated using field measurements numerical simulations. A two-dimensional, variably saturated model (VAM2D) was used to characterize the hillslope aquifer delineate mechanisms. Spatially varying along transect described preceding paper as input for analyses. Simulations indicated that heterogeneous provides hydrogeological conditions confined unconfined...

Deep learning (DL) techniques have expedited successful applications in computed tomography (CT) imaging field and obtained remarkable outcomes. Most of the require precollection large numbers low-dose/high-dose CT image pairs training network a supervised end-to-end manner. However, there are some evident limitations to such manner: 1) it is time intensive acquire sufficient sample pairs, as expected, low-dose images usually simulated from high-dose due radiation exposure patients. In...

Fasting blood glucose (FBG) is a recognized risk factor for Ischemic Stroke, but little research has examined the interaction among FBG, Platelet Distribution Width (PDW) and severity of neuronal damage. Thus, present study constructs moderated mediation model aimed to elucidate relationships PDW, NIHSS scores in patients with acute ischemic stroke (AIS).

Water resource regulation is convenient for humans, but also changes river hydrology and affects aquatic ecosystems. This study combined a field investigation two-dimensional hydrodynamic model (MIKE21) to simulate the distribution from 1 March 30 April of 2008–2013 establish HDI (habitat depth suitability index) HVI velocity based on static hydraulic conditions at typical points. Additionally, by using MIKE21 state in area under 20 flow 530–1060 m3/s, combining these states with HCI cover...

Recently, deep learning(DL) methods have been proposed for the low-dose computed tomography(LdCT) enhancement, and obtain good trade-off between computational efficiency image quality. Most of them need large number pre-collected ground-truth/high-dose sinograms with less noise, train network in a supervised end-to-end manner. This may bring major limitations on these because such low-dose/high-dose training sinogram pairs would affect network's capability sometimes ground-truth are hard to...

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a potential therapeutic target in acute coronary syndromes. Although recent evidence does not support the routine use of manual thrombus aspiration (TA) patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous intervention (PPCI), TA associated significant improvement reperfusion, especially high burden (HTB). We hypothesized that would reduce serum Lp-PLA2 levels STEMI PPCI HTB.Our study cohort included 320...

Xiaowan Reservoir was created by the construction of Dam on Mekong River. This dam is second highest arch in world with 292 m tall and 902 long. The reservoir about 178km from upstream to dam, surface area around 189 km2. water depth near very deep, which normally varies 200 270m seasonally. For such a deep reservoir, vertical temperature distribution show significant stratified structure. In this study, three dimensional numerical model developed for simulating flow fields dam. effects...

<title>Abstract</title> <bold>Objective: </bold>Our study aims to explore the relations among thyroid morphology and hormones sex, age in rhesus monkeys, so establish a range of reference values for serological testing ultrasonography Chinese monkeys. Furthermore, we analyze common diseases incidences abnormal these <bold>Methods: </bold>1027 healthy monkeys were divided into infant, juvenile, adolescent, adult, middle-aged, elderly groups based on their age. The (TT3, TT4, FT3, FT4, TSH,...

The CYP450 enzyme is a superfamily ubiquitously found in nearly all organisms, playing vital role the metabolism of both endogenous and exogenous compounds, biosynthesis. Unfortunately, an understanding its classification, functions, expression characteristics, other biological traits

This paper presents the operational principle, architecture design, resonance characteristics and FEM simulation of a new fully decoupled dual-mass silicon micro-gyroscope. The drive motion sense micro-gyroscope studied in this are isolated from each other, mechanical quadrature error is thus dramatically suppressed due to minimizing undesired coupling between modes. Moreover,two identical single-mass gyroscopes adopted coupled with beams form micro-gyroscope, which provides enhanced common...

An EEG integrated analysis system was developed by LabVIEW, which expanded bandwidth above 3 (KHz) to collect more useful information. The novel preamplifier designed and the of data acquisition, implemented, could analyze with an optional combination time domain, frequency time-frequency, nonlinearity, chaotics, several spectral analysis, wavelets other special algorithms under multi-parameter. syncretized a variety dedicated processing methods meet need feature extraction for weak signals....

Epilepsy is a brain dysfunction disease, which caused by neuron excessive discharge. The damage induced seizure irreversible, so it necessary to propose new method prevent epileptic and protect the brain. Therefore, best way predict preictal state accurately give preventive treatment. In this paper, calculation of largest Lyapunov exponent based on improved Wolf algorithm was used analyze characteristics nonlinear dynamics extract feature model among rats' preictal, ictal normal state,...

To meet the needs of design and analysis for special ultrasound transducer complex multi-parameters array ultrasonic transducers, a robotic system was developed to measure analyze feature field. The integrated with mechanical robot, electronic control, hydrophone measurement software modules. can automatically scan whole field in any direction locate at point high spatial resolution, precise (0.05 mm) good frequency response overcome problems measurement, modeling transducer. A standard...

Abandoned landfill sites pose an uncertain threat to water quality and environmental health. These sites, oftenlocated in rural areas, historically had little or no regulation for use maintenance, it is often unknown whathazardous materials may have been discarded. Evaluation remediation of these can be extremely costly.Numerical models contaminant fate transport a cost-effective tool assessing the potential hazards that asite evaluating measures, but seldom are available which simulate...

This paper focuses on the effect of capillary pressure hysteresis predicting extent contaminated area caused by a lighter than water nonaqueous phase liquid (LNAPL) spill in subsurface and investigates factors that determine when this is important. The numerical code used to model LNAPL spills T2VOC module TOUGH family codes, developed at Lawrence Berkeley National Laboratory. For study, was modified allow for hysteretic behavior pressure-saturation constitutive relationship. Comparisons...

Abstract Background: Atrial fibrillation (AF) is a common arrhythmia that induces disability or death; however, the underlying pathogenesis yet unclear. This study aimed to investigate expression of matrix metalloproteinase-9 (MMP-9) in rheumatic valvular heart disease (RVHD) and its value predicting AF. Methods: In this single-center, prospective case-control study, 30 patients who received valve replacement for treatment RVHD Cardiac Major Vascular Department, Yue Bei People’s Hospital...

The effects of temperature variation on the system performance is discussed in this paper. characteristic natural frequency and quality factor analyzed theoretically firstly. Then simulation models open-loop drive system, closed-loop sense quadrature correction are constructed to simulate scale zero bias. results demonstrate relative change that 1.35%, almost decreases by 67 times bias 0.2789°/s, 364 system. At same time, 0.000029%, 46551 1.2×10 -11 °/s, 2.3×10 10 which shows proposed method...

The thermal analysis and simulation of on-chip temperature control technology in the micro-gyroscope is researched. According to dissipation mechanism, resistance model established. equantions conduction radiation are deduced. lumped parameter model, transient response proof mass derived. Theoretical indicates temperatures micro-heater respectively 136.79°C 59.95°C equilibrium conditions. Ansys gyroscope constructed optimize distribution steady-state. results show that maximum glass...