A5076940782- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Genetic Mapping and Diversity in Plants and Animals
- Peroxisome Proliferator-Activated Receptors
- CRISPR and Genetic Engineering
- Thermal and Kinetic Analysis
- Energetic Materials and Combustion
- Reproductive Physiology in Livestock
- Animal Genetics and Reproduction
- Genomic variations and chromosomal abnormalities
- Microbial Metabolism and Applications
- Gout, Hyperuricemia, Uric Acid
- Animal Nutrition and Physiology
- Virus-based gene therapy research
- VLSI and FPGA Design Techniques
- Reproductive Biology and Fertility
- Adipose Tissue and Metabolism
- Combustion and Detonation Processes
- Boron and Carbon Nanomaterials Research
- Engineering Applied Research
- Ruminant Nutrition and Digestive Physiology
- Cancer Research and Treatments
- RNA Interference and Gene Delivery
- Chromosomal and Genetic Variations
Gansu Agricultural University
2019-2025
Nanjing University of Science and Technology
2023-2024
Yangzhou University
2011-2020
Chinese Academy of Agricultural Sciences
2015-2019
Institute of Animal Sciences
2015-2016
China Agricultural University
2015
Abstract Chinese indigenous sheep can be classified into three types based on tail morphology: fat-tailed, fat-rumped, and thin-tailed sheep, of which the typical breeds are large-tailed Han Altay Tibetan respectively. To unravel genetic mechanisms underlying phenotypic differences among with tails different types, we used ovine high-density 600K SNP arrays to detect genome-wide copy number variation (CNV). In 371, 301, 66 CNV regions (CNVRs) lengths 71.35 Mb, 51.65 10.56 respectively, were...
The hypothalamus (hyp) serves as the regulatory hub of neuroendocrine system, synthesizing and secreting reproductive hormones that modulate estrus, follicular maturation, embryonic development in goats. This study employed RNA-seq analysis to examine gene expression hypothalamic tissue Yunshang black goats during luteal phase with high fecundity (LP_HY), low (LP_LY), (FP_HY), (FP_LY). Differential long non-coding RNAs (DE lncRNAs) differential mRNAs mRNAs) were subjected Gene Ontology (GO)...
Hulun Buir sheep of similar genetic background were divided into two lines based on tail types: Small- and big fat-tailed. To explore the molecular mechanism fat deposition in tails, we firstly evaluated morphology transcription level differences between these lines. RNA-Seq technology was used to identify differentially expressed genes (DEGs) phenotypic extremes sizes. Five comparisons performed taking account factors, sex type. We screened out 373 DEGs big-tailed small-tailed sheep, 775...
The purpose of this study was to determine the mechanism Astragalus activity on immune function, rumen microbiota structure, and fermentation early-weaned lambs.Thirty healthy lambs with similar body weights (17.42 ± 2.02 kg) were selected for feeding experiment. control group (KB) fed a basal diet, (HQ) 0.3% additive basis basic diet. formal trial period 60 days. results showed that concentrations blood immunoglobulin A (IgA) M (IgM) in HQ significantly higher than those KB (P < 0.05)....
Artificial selection has played a critical role in animal breeding. Detection of artificial footprints genomic regions can provide insights for understanding the function specific phenotypic traits and better guide To more fully understand relationship between composition diversity arising from breed development, genome-wide scan was conducted using an OvineSNP50 BeadChip integrated haplotype score fixation index analyses to detect signatures on X chromosome three sheep breeds. We identified...
Abstract Sheep reproductive performance is one of the important economic traits in sheep farming. The bone morphogenetic protein receptor 1B (BMPR1B) gene and may play an role fertility. This study was to investigate association blood BMPR1B expression with sheep. Mongolian single twin births polytocous Small Tail Han were selected due differences birth numbers. mRNA measured by a reverse transcription-polymerase chain reaction as well enzyme-linked immunosorbent assay samples results...
Chinese indigenous sheep breeds can be classified into the following three categories by their tail morphology: fat-tailed, fat-rumped and thin-tailed sheep. The typical corresponding to fat-rumped, are large-tailed Han, Altay, Tibetan sheep, respectively. Detection of copy number variation (CNV) selection signatures provides information on genetic mechanisms underlying phenotypic differences different types.In this study, PennCNV software F-statistics (FST) were implemented detect CNV...
The aim of this study was to clone the heart-type fatty acid binding protein (H-FABP) gene Xuhuai goat, explore it bioinformatically, and analyze subcellular localization using enhanced green fluorescent (EGFP). results showed that coding sequence (CDS) length goat H-FABP 402 bp, encoding 133 amino acids (GenBank accession number AY466498.1). cDNA compared with corresponding region human, chicken, brown rat, cow, wild boar, donkey, zebrafish. similarity were 89%, 76%, 85%, 84%, 93%, 91%,...
Fuel boron (B) has the advantage of a high calorific value. However, coating oxide (B2O3) is present on outermost layer B particles, which will greatly hinder oxidation B. In this study, high-energy 1,3,5,7-tetranitro-1,3,5,7-tetraazacyclooctane (HMX) used to increase activity powder, so as enhance ignition and combustion performance Samples with various HMX contents are successfully prepared by recrystallization solvent evaporation method. The study morphology composition reveals that...
To explore the possibility of transgenic animals by testicular injection, goat heart-type fatty acid binding protein (H-FABP) expression vector pEGFP-H-FABP was injected into testis 6 mice randomly liposome mediated transfection. By detection slice, sperm fluorescence and DNA PCR, exogenous gene expressed in parental mice. The at different levels both F1 generation gave birthed treated male normal female F2 generated mating could be detected that with positive rates 4% 30.23%, respectively....
Goat (Capra hircus) stearoyl-CoA desaturase 1 (SCD1) plays a crucial role in fatty acid metabolism including milk and muscular acid.This study investigated the expression of SCD1 gene goat examined its inheritability transgenic mice goats.Our results suggested possibility generating goats by sperm-mediated transfer (SMGT).The genes mammary gland tissues was aligned with GEO database, tested qRT-PCR.F were mated then target protein level F 2 mice, as well fat content muscle...