A5101604909- Gut microbiota and health
- Extracellular vesicles in disease
- Advanced Measurement and Metrology Techniques
- Circular RNAs in diseases
- Cancer Immunotherapy and Biomarkers
- Diet and metabolism studies
- Optical measurement and interference techniques
- MicroRNA in disease regulation
- RNA and protein synthesis mechanisms
- Plant Molecular Biology Research
- International Student and Expatriate Challenges
- Cell Adhesion Molecules Research
- Cruise Tourism Development and Management
- Amoebic Infections and Treatments
- Genetics, Bioinformatics, and Biomedical Research
- Venomous Animal Envenomation and Studies
- Epigenetics and DNA Methylation
- Bone fractures and treatments
- Reproductive System and Pregnancy
- Adaptive optics and wavefront sensing
- Uterine Myomas and Treatments
- Seed Germination and Physiology
- S100 Proteins and Annexins
- Marine Ecology and Invasive Species
- Bacterial Infections and Vaccines
Chongqing Medical University
2024
Liaoning Normal University
2024
Zhejiang University
2014-2024
Second Affiliated Hospital of Zhejiang University
2023-2024
Zhejiang Chinese Medical University
2024
Henan Academy of Agricultural Sciences
2023
Agricultural Genomics Institute at Shenzhen
2023
Chinese Academy of Agricultural Sciences
2023
Huazhong Agricultural University
2021
Yunnan University of Finance And Economics
2020
Abstract Aging‐induced cognitive impairment is associated with a loss of metabolic homeostasis and plasticity. An emerging idea that targeting key metabolites sufficient to impact the function other organisms. Therefore, more metabolism‐targeted therapeutic intervention needed improve impairment. We first conducted untargeted metabolomic analyses 16S rRNA identify aging‐associated adaption intestinal microbiome change. Untargeted plasma revealed L‐arginine was altered during aging process....
Herbaceous peony (Paeonia lactiflora Pall.) is a traditional flower in China and wedding attractive worldwide. In its colour, yellow the rarest which ten times price of other colours. However, breeding new P. varieties using genetic engineering severely limited due to little-known biochemical molecular mechanisms underlying characteristic formation. this study, two cDNA libraries generated from chimaera with red outer-petal inner-petal were sequenced an Illumina HiSeq™ 2000 platform....
Abstract The progression of colorectal cancer is closely associated with diet. Fasting-mimicking diet (FMD) a promising type dietary intervention that have beneficial effects in the prevention and treatment various cancers. We investigated therapeutic effect 4-day FMD against mice through immune cell analysis, microbiota composition analysis anti-PD-1 treatment. These cycles effectively suppressed growth, reduced proliferation angiogenesis, increased tumor-infiltration lymphocytes especially...
Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) are a novel and promising strategy for tissue engineering because of their ability to differentiate into many cell types. We characterized the differentiation WJ-MSCs endometrial epithelial (EEC)-like stromal (ESC)-like assessed effect 17β-estradiol 8-Br-cAMP on system. were treated in two ways EEC-like ESC-like respectively: cocultured with ESCs control/differentiation medium (17β-estradiol, growth factors); cultured (8-Br-cAMP alone...
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Pseudorabies virus (PRV) infection causes enormous economic losses to the pork industry and severe health consequences in many hosts. Annexin A2 (ANXA2) is a membrane-associated protein with various intracellular functions associated viral infections. However, role of ANXA2 alphaherpesvirus replication still not explored. In present study, we identified interaction between PRV US3. The deficiency significantly restricted proliferation. or US3 overexpression led extracellular translocation....
Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) exhibit strong and powerful potential in repairing different diseases. The expression profile of circular RNA (circRNA) provides valuable insight for regulation the repair process exploration reparative effect mechanisms. Human endometrial stromal (ESCs) were cultured with mifepristone to obtain damaged ESCs, which then cocultured or without WJ-MSCs (cocultured group versus non-cocultured group) observe upon ESCs by WJ-MSCs. CircRNA...
Under the background of economic transformation, tourism is one most dynamic and promising tertiary industries. How to improve competitiveness has become a new idea for industrial upgrading in various regions. This paper builds an evaluation system consisting five major aspects, based on data 75 tourist destinations; then, uses cluster analysis classify cities, logistic regression, SVM random forest methods predict sample cities compare advantages disadvantages two - classification...
The binding affinities of protein-nucleic acid interactions could be altered due to missense mutations occurring in DNA- or RNA-binding proteins, therefore resulting various diseases. Unfortunately, a systematic comparison and prediction the effects on protein-DNA protein-RNA (these two mutation classes are termed MPDs MPRs, respectively) is still lacking. Here, we demonstrated that these generate similar different tendencies for free energy changes terms properties mutated residues. We then...
At present, there is a research gap concerning the specific functions and mechanisms of Notch gene family its signaling pathway in jawless vertebrates. In this study, we identified Notch1 homologue (Lr. Notch1) Lethenteron reissneri database. Through bioinformatics analysis, Lr. as likely common ancestor higher vertebrates, indicating high degree conservation pathways. To validate biological function Notch1, conducted targeted silencing L. analyzed resultant expression profile before after...
Background: Angiogenesis plays a crucial role in the growth of colorectal cancer (CRC). Recent studies have identified extracellular vesicles (EVs) tumor microenvironment as important mediators cell-to-cell communication. However, specific and mechanisms CRC-derived EVs regulating angiogenesis remain to be further investigated. Methods: were isolated from conditioned medium CRC cells using ultracentrifugation. We investigated effects HT-29-derived on subcutaneous HT-29 model mice....
In this paper, a high-accuracy calibration method for errors resulted from aberration in long focal length measurement, is presented. Generally, Gaussian Equation used calculation without consideration of the caused by aberration. However, are key factor affecting accuracy measurement system large aperture and lens. We creatively introduce an effective way to calibrate errors, with detailed analysis based on divergent light Talbot interferometry. Aberration simulated Zemax. Then, we achieve...
Severe trauma can lead to amputation of limbs. There is no golden standard or comprehensive evaluation indicator for amputation. It difficult the primary rescue organization focus on most essential indicators and determine whether perform take proper operation.For medical staff in first-line teams disaster relief a common hospital, what should they keep patient's limbs when receive wounded patients with severe trauma?A retrospective case-control study was performed based from January 2013...
In this paper, a high-accuracy calibration method for angular measurement of deformed and curved Moiré patterns, based on template matching algorithm, is presented. We report feasible accurate method, Talbot interferometry deflectometry, to measure long focal-length lenses. Theoretical analysis indicates that the precision mainly influenced by angle patterns. However, it's difficult obtain since patterns derived from experiment are constantly or curved. demonstrate calibrate thus their can...
This paper mainly takes the overseas students in Yunnan universities as main subjects of questionnaire.This studies relationship between cultural identity and learning effectiveness foreign China.Data were collected by questionnaire survey analyzed SPSS statistical software.The results show that, firstly, has a positive impact on outcomes.The higher degree is, better effect can be.Secondly, initiative personality students.That is to say, more active is.Finally, student's identity, effect,...