A5040096850- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Periodontal Regeneration and Treatments
- Pluripotent Stem Cells Research
- 3D Printing in Biomedical Research
- biodegradable polymer synthesis and properties
- Bone Tissue Engineering Materials
- Bone fractures and treatments
- Animal Genetics and Reproduction
- Graphene and Nanomaterials Applications
- Hedgehog Signaling Pathway Studies
- Renal and related cancers
- Wound Healing and Treatments
- Insect and Pesticide Research
- Healthcare and Venom Research
- Bee Products Chemical Analysis
- Reproductive Biology and Fertility
- Biomedical Ethics and Regulation
- Cancer Cells and Metastasis
- Osteoarthritis Treatment and Mechanisms
- Silk-based biomaterials and applications
- Cancer and Skin Lesions
- Plant tissue culture and regeneration
- Genetic and rare skin diseases.
Universidade Federal do Piauí
2014-2025
Morpho (United States)
2025
Universidade Federal de Viçosa
2007-2012
Universidade do Estado de Santa Catarina
2010
Universidade Federal do Espírito Santo
2010
Dentre todas as células-tronco estudadas até o presente momento, mesenquimais (MSC) destacam-se por sua elevada plasticidade, podendo originar tecidos mesodermais e não mesodermais. Além disso, possuem características imunomoduladoras imunossupressoras que ampliam possibilidades de utilização terapêutica. As MSC secretam uma grande variedade citocinas pró anti-inflamatórias fatores crescimento e, meio dessas moléculas bioativas, proporcionam a modulação da resposta inflamatória,...
This article details the in situ preparation of composite scaffolds using polyurethane (PU) and HAp (hydroxyapatite), focusing on unique properties buriti oil (Mauritia flexuosa L.) applicable to tissue engineering. PU derived from vegetable oils, particularly oil, has shown promise bone repair due its rich bioactive compounds. Buriti is an excellent candidate for manufacturing these materials as it compounds such carotenoids, tocopherols, fatty acids, which have antioxidant...
ABSTRACT Introduction/Objectives: Agoutis is a medium‐sized wild rodent with potential for use as an experimental model. This study aimed to evaluate physiological parameters of arrhythmogenesis in this species, by HR‐ECG and VCG techniques, under physical pharmacological containment (ketamine‐xylazine butorphanol). Materials methods: Eight agouti which the were evaluated containment. We cardiac pulmonary foci sounds, made femoral pulse inspection, body score analysis, gestational...
Hydrogels are structures that have value for application in the area of tissue engineering because they mimic extracellular matrix. Naturally obtained polysaccharides, such as chitosan (CH) and cashew gum, materials with ability to form polymeric networks due their physicochemical properties. This research aimed develop a scaffold based on phthalated tree gum test it support growth human mesenchymal stem cells. In this study, phthalation (PCG) was performed by using solvent-free route....
Journal Article Role of autologous mesenchymal stem cells associated with platelet‐rich plasma on healing cutaneous wounds in diabetic mice Get access N. M. Argôlo Neto, Neto Department Veterinary Medicine, Federal University Piauí, Teresina, Brazil Dr Napoleão Martins UFPI Laboratório de Pesquisas Morfológicas em Ciência Animal, Centro Ciências Agrárias Campus Agrícola da Socopo, Universidade do S/N, Teresina Piauí 64049‐550, E‐mail: argolo_napoleao@hotmail.com Search for other works by...
Hydrogels from natural sources are attracting increasing interest due to their ability protect biologically active molecules. Starch extracted cassava tubers is a promising material for synthesizing these hydrogels. Copolymerization of gum and incorporation chlorhexidine digluconate (CLX) into the hydrogels confirmed by changes in crystallographic profile, as observed through X-ray diffraction, shift 1000 cm
Mesenchymal stem cells have been widely used in the treatment of various chronic diseases. The objective this survey was to evaluate therapeutic and regenerative potential from adipose tissue (ASCs) milk production recovery repair injury mastitis goats treated with antimicrobial agents prior cell therapy. After diagnosis gentamicin, eight lactating were selected for cellular subsequent therapy, physical-chemical analysis milk, ultrasonographic histopathological examinations. ASCs taken...
PURPOSE: To evaluate the effects of mesenchymal stem cells (MSC) from eight mice C57BL/6 gfp+ bone marrows expanded in cultures associated with platelets rich plasma (PRP) deriving another mice, repair critical defects calvarial produced twenty-four adult isogenic C57BL/6. METHODS: The animals were submitted to a cranial defect 6.0mm diameter and divided into two equal experimental groups. Control group did not receive treatment treated received MSC pellet containing 1.0 x 10(7) cells/mL...
Purpose: To assess the efficacy of allogeneic mesenchymal stem cells and xenogenic platelet rich plasma in treatment bone failure osteoporotic rabbits secondary to estrogenic deprivation iatrogenic hypercortisolism. Methods: Eight female underwent ovarian resection corticoid therapy induce clinical status osteoporosis. Four failures were produced tibiae, with each being treated hemostatic sponge, allogenic cells, platelet-rich association between both. The animals divided into two groups,...
Background: There are few studies on stem cell isolation in wild animals that provide and culture protocols of these cells vitro. Among the species studied, we present collared peccary (Tayassu tajacu) as a model with potential to obtain use MSC preclinical studies. These phylogenetically close domestic pig, popularly known peccaries found naturally South America, Central America United States. The aim study was establish protocol for isolation, vitro expansion, differentiation assessment...
Tissue engineering aims to recreate natural cellular environments facilitate tissue regeneration. Gelatin methacrylate (GelMA) is widely utilized for its biocompatibility, ability support cell adhesion and proliferation, adjustable mechanical characteristics. This study developed a GelMA graphene bioink platform at concentrations of 1, 1.5, 2 mg/mL enhance scaffold properties applications.
To produce polysaccharide-based hydrogels and cerium (Ce3+) doped hydroxyapatite plus chitosan collagen to enable future applications in the treatment of joint degeneration. Hydrogel production characterization were performed with Fourier transform infrared spectroscopy (FTIR), thermogravimetry analysis (TGA) cytotoxicity testing MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]. A final biomaterial composition was Kelcogel® Gelana (58%), (22.3%), Ce3+ (10.7%) bovine (9%),...
O presente trabalho teve como objetivo avaliar e comparar as alterações bioquímicas hemogasométricas do sangue total canino armazenado em bolsas CPDA-1 CPD/SAG-M. Foram utilizados 14 cães machos, adultos saudáveis, distribuídos dois grupos com sete animais cada, dos quais foi obtido para o estudo. No primeiro grupo (G1), e, no segundo (G2), As amostras foram analisadas para: potássio, sódio, glicose, proteína plasmática total, DPG, pH sangüíneo, pO2 , pCO2 bicarbonato. Os momentos...
Mesenchymal stem cells (MSC) are present in specialized niches perivascular regions of adult tissues and able to differentiate into various cell types, such as those committed repairing. Bone marrow derived MSC from eight young mice C57BL/ 6 gfp(+) were expanded culture for repairing critical defects calvarial bone produced twenty-four isogenic C57BL/6 mice. The animals subjected a cranial defect 6.0mm diameter divided two equal experimental groups. Control group did not receive any...
Abstract Stem cells are present in the adult tissues of most diverse species. Bone marrow is recognized to be exploited site obtain stem and cell progenitors. The objective study was characterize hematopoietic progenitor (HP) morphology analyze performance adherent progenitors (ACPs) cultivated vitro from black‐rumped agouti bone ( Dasyprocta prymnolopha ). aspirates were obtained tibia crest used prepare histological slides identify morphology. Cells also scattered on culture plates for...
PURPOSE: To characterize bone marrow progenitors cells grown in vitro, using native goats from northeastern Brazil as animal model. METHODS: Ten of both genders were used the Piauí Federal University Agricultural Science Center's (UFPI) - Goat Farming Sector. Bone aspirates where taken tibial ridge and seeded on culture plates for isolation, expansion Flow Cytometry (expression markers Oct-3/4, PCNA, Ck-Pan, Vimentina, Nanog). RESULTS: Progenitor showed colonies characterized by presence...
Abstract: The study aimed to isolate, expand, differentiate and characterize progenitor cells existent in the dental pulp of agouti. material was washed with PBS solution dissociated mechanically aid a scalpel blade on plates containing culture medium D-MEM/F-12, incubated at 5% CO2-37⁰C. growth curve, CFU assay, osteogenic/adipogenic differentiation characterization were obtained from isolation. began be released explant tissue around 7th day culture. By 22 culture, reached 80% confluence....
Introduction: Wound healing is a progressive, essential and complex physiological process that occurs as restorative response after tissue injury. It involves three phases: inflammation, proliferation maturation. Exogenous, endogenous pathological factors may interfere in the cicatricial humans animals by altering balance between synthesis, degradation remodelling of collagen elastic fibres. Diabetes mellitus progressive metabolic disease alters elastogenesis collagenesis induces delays...