A5078225752- Semiconductor Quantum Structures and Devices
- Antimicrobial Peptides and Activities
- GaN-based semiconductor devices and materials
- Quantum and electron transport phenomena
- Semiconductor materials and devices
- Biochemical and Structural Characterization
- Semiconductor materials and interfaces
- Advanced Chemical Physics Studies
- Physics of Superconductivity and Magnetism
- Essential Oils and Antimicrobial Activity
- Quantum Dots Synthesis And Properties
- Ga2O3 and related materials
- Advanced Semiconductor Detectors and Materials
- ZnO doping and properties
- Surface and Thin Film Phenomena
- Metal and Thin Film Mechanics
- Amphibian and Reptile Biology
- Silicon and Solar Cell Technologies
- Parasites and Host Interactions
- Silicon Nanostructures and Photoluminescence
- Magnetic properties of thin films
- Psidium guajava Extracts and Applications
- Neurobiology and Insect Physiology Research
- Electron and X-Ray Spectroscopy Techniques
- Insect Resistance and Genetics
Universidade de Brasília
2016-2025
Universidade de São Paulo
2000-2024
Universidade Federal do Piauí
2012-2024
Universidade Federal de São Paulo
2022-2024
Universidade Federal do Delta do Parnaíba
2020-2024
Ministry of Science, Technology and Innovation
2024
Brazilian Agricultural Research Corporation
2002-2022
Rede de Química e Tecnologia
2016-2022
Universidade do Porto
2016-2022
Brazilian Society of Tropical Medicine
2021
We present first-principles calculations of the thermodynamic and structural properties cubic ${\mathrm{In}}_{x}{\mathrm{Ga}}_{1\ensuremath{-}x}\mathrm{N}$ ${\mathrm{Al}}_{x}{\mathrm{Ga}}_{1\ensuremath{-}x}\mathrm{N}$ alloys. They are based on generalized quasichemical approach to disorder composition effects a pseudopotential-plane-wave approximation for total energy. The cluster treatment is study influence biaxial strain. find remarkable suppression phase separation in...
The electronic band structures of silicon and the zinc-blende-type III-N semiconductor compounds BN, AlN, GaN, InN are calculated by using self-consistent full potential linear augmented plane wave method within local-density functional approximation. Lattice constant, bulk modulus, cohesive energy obtained from relativistic total-energy calculations for Si nitrides. Band total density states (DOS) presented. role played effects on DOS is discussed. In order to provide important...
The aim of this study was to investigate the antinociceptive and anti-inflammatory activities epiisopiloturine (1), an imidazole alkaloid found in leaves Pilocarpus microphyllus. activity 1 evaluated using several agents that induce paw edema peritonitis Swiss mice. Paw tissue peritoneal fluid samples were obtained determine myeloperoxidase (MPO) or tumor necrosis factor (TNF)-α interleukin (IL)-1β levels. by acetic acid-induced writhing, hot plate test, pain induction formalin. Compared...
Schistosomiasis, caused by blood flukes of the genus Schistosoma, still imposes a considerable public health burden on large parts world. The control this disease depends almost exclusively drug praziquantel, and there are no alternative drugs in sight. Natural compounds have recently attracted significant attention due to their relevance parasitic infection potential development into new therapeutic agents. Epiisopiloturine is an imidazole alkaloid isolated from leaves Pilocarpus...
The present study describes the development of a green synthesis silver nanoparticles reduced and stabilized by exuded gum from Anacardium occidentale L. evaluates in vitro their antibacterial cytotoxic activities. Characterization cashew gum-based (AgNPs) was carried out based on UV-Vis spectroscopy, transmission electron microscopy dynamic light scattering analysis which revealed that synthesized were spherical shape, measuring about 4 nm size with uniform dispersal. AgNPs presented...
Silver nanoparticles have been shown to possess considerable antibacterial activity, but in vivo applications limited due the inherent, low, toxicity of silver. On other hand, silver could provide cutaneous protection against infection, their ability liberate ions via a slow release mechanism, and broad-spectrum antimicrobial action. Thus, this work, we describe development carboxymethyl cellulose-based hydrogel containing nanoparticles. The were prepared situ, utilizing two variants cashew...
Type I collagen is an abundant natural polymer with several applications in medicine as matrix to regenerate tissues. Silver nanoparticles important nanotechnology material many utilities some areas such medicine, biology and chemistry. The present study focused on the synthesis of silver (AgNPs) stabilized type (AgNPcol) build a nanomaterial biological utility. Three formulations AgNPcol were physicochemical characterized, antibacterial activity vitro cell viability assays analyzed. was...
Schistosomiasis affects million people and its control is widely dependent on a single drug, praziquantel. Computational chemistry has led to the development of new tools that predict molecular properties related pharmacological potential. We conducted theoretical study imizadole alkaloids Pilocarpus microphyllus (Rutaceae) with schistosomicidal properties. The molecules epiisopiloturine, epiisopilosine, isopilosine, pilosine, macaubine were evaluated using theory models (B3lyp/SDD,...
Abstract Candida albicans is a major cause of human infections, ranging from relatively simple to treat skin and mucosal diseases systemic life-threatening invasive candidiasis. Fungal infections treatment faces three challenges: the limited number therapeutic options, toxicity available drugs, rise antifungal resistance. In this study, we demonstrate activity mechanism action peptides ToAP2 NDBP-5.7 against planktonic cells biofilms C. . Both were active cells; however, was more produced...
Amphibian skin secretions are known as a rich source of biologically active molecules, most which alkaloids, biogenic amines, and peptides. Dermaseptins class antimicrobial peptides present in tree frogs the Phyllomedusa genus. They cationic molecules 28-34 residues that permeabilize membrane Gram-positive Gram-negative bacteria, yeasts, filamentous fungi, showing little or no hemolytic activity. This work reports isolation, molecular mass analysis, primary structure determination,...
Phase separation suppression due to external biaxial strain is observed in InxGa1−xN alloy layers by Raman scattering spectroscopy. The effect taking place thin epitaxial pseudomorphically grown molecular-beam epitaxy on unstrained GaN(001) buffers. Ab initio calculations carried out for the free energy predict and measurements confirm that suppress formation of phase-separated In-rich quantum dots layers. Since are effective radiative recombination centers InGaN, we conclude quenches an...
A microscopic model is proposed which explains recent observations that acceptor shallow levels in crystalline silicon can be inactivated by atomic hydrogen. We are assuming substitutionalboron-interstitial-hydrogen complex pairs being formed passivate the action of boron impurity. Rigorous self-consistent calculations show level removed from gap and electrical activity clearly neutralized.
Antimicrobial peptides are an abundant group of proteinaceous compounds widely produced in the plant kingdom. Among them, gamma-thionin family, also known as defensins, represents one typical family and comprises low molecular mass cysteine-rich proteins, usually cationic distributed different tissues. Here, we report purification characterization a novel from cowpea seeds (Vigna unguiculata), named Cp-thionin II, with bactericidal activity against Gram-positive Gram-negative bacteria. Once...
Abstract Objectives The aim of this work was to investigate the antinociceptive property α-phellandrene (α-PHE) in experimental nociception models and possible mechanisms involved. Methods Mass spectrometry used evaluate purity molecular mass α-PHE. Macrophages from mice peritoneal cavity were an MTT test. Rodents tests chemical mechanical nociception. In study mechanisms, animals treated with pharmacological tools then submitted glutamate Key findings α-PHE 98.2% 136.1 Da. did not show...
There are ethnopharmacological reports supporting the use of neem (Azadirachta indica A. Juss) leaf against bacterial and worm infections. However there is a lack studies about its effect on biofilm formation Schistosoma mansoni worms. This study in vitro effects ethanolic extract (Neem EE) Methicillin-resistant Staphylococcus aureus (MRSA) planktonic aggregation formation, S. Quantification Azadirachtin (AZA), thought to be one their main compounds related biological effects, was performed....
Schistosomiasis is a serious disease currently estimated to affect more that 207 million people worldwide. Due the intensive use of praziquantel, there increasing concern about development drug-resistant strains. Therefore, it necessary search for and investigate new potential schistosomicidal compounds. This work reports in vivo effect alkaloid epiisopiloturine (EPI) against adults juvenile worms Schistosoma mansoni. EPI was first purified its thermal behavior theoretical solubility...