- Seaweed-derived Bioactive Compounds
- Agricultural and Food Sciences
- Healthcare during COVID-19 Pandemic
- Science and Education Research
- Education during COVID-19 pandemic
- Chemotherapy-induced organ toxicity mitigation
- Phytochemistry Medicinal Plant Applications
- Oral and gingival health research
- Polysaccharides and Plant Cell Walls
- Long-Term Effects of COVID-19
- Sulfur Compounds in Biology
- Echinoderm biology and ecology
- Alcohol Consumption and Health Effects
- Oral microbiology and periodontitis research
- Ginkgo biloba and Cashew Applications
- Oral health in cancer treatment
- Renin-Angiotensin System Studies
- Apelin-related biomedical research
- Bone health and treatments
- Helicobacter pylori-related gastroenterology studies
- Bee Products Chemical Analysis
- Psidium guajava Extracts and Applications
- Healthcare Regulation
- Synthesis and biological activity
- Phytochemistry and Bioactivity Studies
Ordem dos Médicos
2023
Universidade do Vale do Paraíba
2023
Centro Regional de Derechos Humanos y Justicia de Género, Corporación Humanas
2021-2023
Secretaria de Estado de Segurança Pública
2022
Universidade Federal do Piauí
2015-2021
Universidade Federal do Ceará
2020
United States Patent and Trademark Office
2020
Universidade Federal do Delta do Parnaíba
2020
Universidade de São Paulo
2017
The aim of this study was to investigate whether experimental periodontitis cause changes the renal tissues and imbalance in oxidative stress kidneys.Twenty-two female Wistar rats were separated into two groups: control periodontitis. We assessed following parameters: gingival bleeding index (GBI), tooth mobility, gum malondialdehyde (MDA), myeloperoxidase (MPO) activity, probing pocket depth (PPD), alveolar bone loss (ABL) for periodontal tissues; histomorphometric measures associated with...
Damage caused by periodontitis not only affects periodontal tissues, but also increases the severity of various illnesses such as rheumatoid arthritis, diabetes, and liver diseases. The aim this study is to investigate association between induced damage through its systemic effects on liver.Twenty rats were divided into two groups: control periodontitis. following parameters evaluated: gingival bleeding index (GBI), probing depth (PD), myeloperoxidase (MPO) activity, alveolar bone loss (ABL)...
Introdução: O sono corresponde a um evento fisiológico de influências neurológicas e endócrinas que promove diversos benefícios para o organismo, como fortalecimento do sistema imune regulação estresse emocional. Estudantes Medicina são especialmente acometidos por distúrbios devido à privação horas sono, acarreta danos saúde, tanto física quanto mental, comprometimento rendimento acadêmico. Objetivo: Analisar qualidade em estudantes seus prejuízos saúde desempenho acadêmico desse grupo...
β-Caryophyllene (BCP) is a sesquiterpene that shows high potential in pharmacological applications. However, these have been drastically limited by the respective volatility and poor water solubility. The present study investigates formation of inclusion complexes between BCP methyl-β-cyclodextrin (MβCD) promote significant improvement anti-inflammatory, gastric protection, antioxidant activities relative to neat BCP. It shown solubility significantly increased through complexation phase...
Abstract Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study aimed to determine the primary structure and investigate peptides obtained from cutaneous amphibian, Leptodactylus vastus , a source molecules. The possessed amino acid sequences, GVVDILKGAAKDLAGH GVVDILKGAAKDLAGHLASKV, monoisotopic masses [M + H] ± = 1563.8 Da 2062.4 Da, respectively. molecules were characterized class ocellatins...
Background and Objective Periodontitis may promote harmful systemic effects such as changes in hepatic tissues. The purpose of this study was to investigate whether the steatosis oxidative stress caused by experimental periodontitis are reversible liver. Material Methods Twenty‐four rats were divided into three groups: control, P20‐20 (20 days with 20 without periodontitis, verify reversibility injuries). following parameters assessed: gingival bleeding index, probing pocket depth,...
This study aimed to evaluate the effect of Lactobacillus reuteri DSM 17938 (DSM) on ethanol-induced gastric injury, and if its possible mechanism action is related inhibiting transient receptor potential vanilloid type 1 (TRPV1). We evaluated supplementing 108 CFU•g body wt−1•day−1 injury. significantly reduced ulcer area (1.940 ± 1.121 mm2) with 3 days pretreatment. The effects supplementation were reversed by Resiniferatoxin (RTX), TRPV1 agonist (3 nmol/kg p.o.). Substance P (SP) (1 μmol/L...
Intestinal mucositis is a common complication associated with 5-fluorouracil (5-FU), chemotherapeutic agent used for cancer treatment. Cashew gum (CG) has been reported as potent anti-inflammatory agent. In the present study, we aimed to evaluate effect of CG extracted from exudate Anacardium occidentale L. on experimental intestinal induced by 5-FU. Swiss mice were randomly divided into seven groups: Saline, 5-FU, 30, 60, 90, Celecoxib (CLX), and CLX + 90 groups. The weight was measured...
Anadenanthera colubrina var. cebil (Griseb.) Altschul (Fabaceae family), commonly known as the red angico tree, is a medicinal plant found throughout Brazil's semi-arid area. In this study, chemical analysis was performed to investigate antidiarrheal activity and safety profile of gum (RAG), biopolymer extracted from trunk exudate A. colubrina. Upon FT-IR spectroscopy, RAG showed bands in regions 1608 cm-1, 1368 1029 which relate vibration O-H water molecules, deformation C-O bands,...
Diarrhoea is a significant health problem for children in developing countries that causes more than 1 million deaths annually. This study aimed to evaluate the antidiarrhoeal effect of sulphated polysaccharide (PLS) from alga Gracilaria caudata rodents. For evaluation, acute diarrhoea was induced Wistar rats (150-200 g) by administration castor oil (10 mg/kg). Then, different parameters, including enteropooling and gastrointestinal transit its pharmacological modulation opioid cholinergic...
Bergenin, a compound derived from gallic acid, is secondary metabolite of the plant Peltophorum dubium (Spreng.) Taub.In this study, we aimed to characterize ability bergenin eliminate radicals in non-biological systems.We evaluated bergenin's protect erythrocytes oxidative damage biological system. We have elucidated structure using nuclear magnetic resonance, X-ray diffraction, Fourier transform infrared spectroscopy, and differential scanning calorimetry. then its antioxidant capacity...
Topical anti-inflammatory action of Caryocar villosum oil (Aubl)Pers.William Kalhy, Silva Xavier, Benedito Junior Medeiros, Clarissa Lima, Hugo Alexandre Favacho, Eloisa Helena de Aguiar Andrade, Railda Neyva, Moreira Araujo, Lourivaldo Santos