A5082538056- Antimicrobial Peptides and Activities
- RNA and protein synthesis mechanisms
- Radiopharmaceutical Chemistry and Applications
- Eosinophilic Disorders and Syndromes
- Psidium guajava Extracts and Applications
- Peptidase Inhibition and Analysis
- Cancer Research and Treatment
- Galectins and Cancer Biology
- Machine Learning in Bioinformatics
- Bioactive natural compounds
- Cancer Cells and Metastasis
- Lipid Membrane Structure and Behavior
- Polydiacetylene-based materials and applications
- Biochemical and Structural Characterization
- Occupational exposure and asthma
- Plant Stress Responses and Tolerance
- Traditional and Medicinal Uses of Annonaceae
- Advanced Proteomics Techniques and Applications
- Cell Adhesion Molecules Research
- Phytochemicals and Antioxidant Activities
- Insect Resistance and Genetics
- Antioxidant Activity and Oxidative Stress
- Advanced Drug Delivery Systems
- Neuropeptides and Animal Physiology
- Asthma and respiratory diseases
University of Lisbon
2019-2023
Universidade Nova de Lisboa
2017
Breast cancer tissue overexpresses fucosylated glycans, such as sialyl-Lewis X/A (sLe
The aims of this study were to produce poly-ɛ-caprolactone lipid-core nanocapsules containing lycopene-rich extract from red guava (LEG), characterize those nanoparticles and evaluate their cytotoxic effects on human breast cancer cells. Lipid-core the (nanoLEG) produced by method interfacial deposition preformed polymer. characterized Dynamic Light Scattering (DLS), Polydispersity Index, Zeta Potential, pH, Encapsulation Efficiency, Nanoparticle Tracking Analysis (NTA), Atomic Force...
Abstract Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study aimed to determine the primary structure and investigate peptides obtained from cutaneous amphibian, Leptodactylus vastus , a source molecules. The possessed amino acid sequences, GVVDILKGAAKDLAGH GVVDILKGAAKDLAGHLASKV, monoisotopic masses [M + H] ± = 1563.8 Da 2062.4 Da, respectively. molecules were characterized class ocellatins...
Abstract Tryptophyllins constitute a heterogeneous group of peptides that are one the first classes identified from amphibian’s skin secretions. Here, we report structural characterization and antioxidant properties novel tryptophyllin‐like peptide, named PpT‐2, isolated Iberian green frog Pelophylax perezi . The secretion P was obtained by electrical stimulation fractionated using RP‐HPLC. De novo peptide sequencing conducted MALDI MS/MS. primary structure PpT‐2 (FPWLLS‐NH 2 ) confirmed...
Snake venoms are important sources of bioactive molecules, including those with antiparasitic activity. Cathelicidins form a class such which produced by variety organisms. Batroxicidin (BatxC) is cathelicidin found in the venom common lancehead (
The existence of encrypted fragments with antimicrobial activity in human proteins has been thoroughly demonstrated the literature. Recently, algorithms for large-scale identification these segments whole proteomes were developed, and pervasiveness this phenomenon was stated. These typically mine cationic amphiphilic proteins, which, when synthesized as individual polypeptide sequences, exert by membrane disruption. In present report, reference proteome submitted to software kamal uncovering...
Eosinophils are multifunctional cells with several functions both in healthy individuals, and those diseases. Increased number morphological changes eosinophils have been correlated the severity of an acute asthma exacerbation. We measured obtained from controls individuals using Atomic Force Microscopy (AFM). In control samples, showed more rounded morphologies some spreading, while activated symptomatic were presenting emission multiple pseudopods. separate granules close to suggesting...