A5037750684- Antimicrobial Peptides and Activities
- Antifungal resistance and susceptibility
- Polysaccharides and Plant Cell Walls
- Essential Oils and Antimicrobial Activity
- Nanocomposite Films for Food Packaging
- Phytochemicals and Medicinal Plants
- Neurobiology and Insect Physiology Research
- Legionella and Acanthamoeba research
- Microbial Metabolites in Food Biotechnology
- Enzyme Production and Characterization
- Polysaccharides Composition and Applications
- Probiotics and Fermented Foods
- Phytochemistry and Bioactivity Studies
- Food Safety and Hygiene
- Bioactive Natural Diterpenoids Research
- Nicotinic Acetylcholine Receptors Study
- Nutritional Studies and Diet
- Piperaceae Chemical and Biological Studies
- Seaweed-derived Bioactive Compounds
- Traditional and Medicinal Uses of Annonaceae
- Agricultural and Food Sciences
- Fungal Infections and Studies
- Antioxidant Activity and Oxidative Stress
- Bioactive natural compounds
- Neuropeptides and Animal Physiology
Universidade de Brasília
2019-2025
Universidade Federal do Piauí
2015-2017
Abstract Candida albicans is a major cause of human infections, ranging from relatively simple to treat skin and mucosal diseases systemic life-threatening invasive candidiasis. Fungal infections treatment faces three challenges: the limited number therapeutic options, toxicity available drugs, rise antifungal resistance. In this study, we demonstrate activity mechanism action peptides ToAP2 NDBP-5.7 against planktonic cells biofilms C. . Both were active cells; however, was more produced...
Paracoccidioides spp. are thermodimorphic fungi that cause a neglected tropical disease (paracoccidioidomycosis) is endemic to Latin America. These inhabit the soil, where they live as saprophytes with no need for mammalian host complete their life cycle. Despite this, developed sophisticated virulence attributes allowing them not only survive in tissues but also disease. A hypothesis selective pressures driving emergence or maintenance of soil interaction predators such amoebae and...
Amphibian skin is a multifunctional organ that plays key roles in defense, breathing, and water balance. In this study, secretion samples of the fire salamander (Salamandra salamandra) were separated using RP-HPLC de novo sequenced MALDI-TOF MS/MS. Next, we used an silico platform to screen antioxidant molecules framework density functional theory. One identified peptides, salamandrin-I, [M + H]+ = 1406.6 Da, was selected for solid-phase synthesis; it showed free radical scavenging activity...
Abstract Tryptophyllins constitute a heterogeneous group of peptides that are one the first classes identified from amphibian’s skin secretions. Here, we report structural characterization and antioxidant properties novel tryptophyllin‐like peptide, named PpT‐2, isolated Iberian green frog Pelophylax perezi . The secretion P was obtained by electrical stimulation fractionated using RP‐HPLC. De novo peptide sequencing conducted MALDI MS/MS. primary structure PpT‐2 (FPWLLS‐NH 2 ) confirmed...
is one of the agents invasive candidiasis, a life-threatening disease strongly associated with hospitalization, particularly among patients in intensive care units central venous catheters. This study aimed to evaluate synergistic activity antifungal peptide ToAP2 combined fluconazole against
A qualidade microbiológica do leite cru e queijo coalho está diretamente relacionada com a produção comercialização produto. Esta pesquisa objetivou avaliar as condições higiênico-sanitárias por meio da detecção de microrganismos indicadores contaminação comercializados em mercados públicos cidade Parnaíba, Piauí. Foram coletadas 16 amostras (8 conservadas refrigeração 8 sem conservação) quatro distintos, no período abril outubro 2012. Na análise cru, 11 das apresentaram números elevados...
Extratos de plantas possuem compostos bioativos com múltiplas possibilidades aplicação na indústria biotecnológica, farmacêutica e alimentícia. Este trabalho avaliou extratos obtidos da espécie Euphorbia tirucalli L. cultivada no litoral do estado Piauí. Foram quantificados fenólicos totais avaliadas pelas metodologias DPPH● ABTS●+ as atividades antioxidantes presente nos acetônicos ou hidrometanólicos por agitação contínua ultrassom. A viabilidade celular foi morfológica metabolicamente...