A5037434958- Phytochemistry Medicinal Plant Applications
- Agricultural and Food Sciences
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Plant-Derived Bioactive Compounds
- Essential Oils and Antimicrobial Activity
- Plant biochemistry and biosynthesis
- Antioxidant Activity and Oxidative Stress
- Cancer Treatment and Pharmacology
- Bee Products Chemical Analysis
- Hibiscus Plant Research Studies
- Moringa oleifera research and applications
- Phytochemical compounds biological activities
- Phytochemistry and Bioactivity Studies
- Polysaccharides Composition and Applications
- Phytochemistry and Bioactive Compounds
- Plant tissue culture and regeneration
- Science and Education Research
- Banana Cultivation and Research
- Ethnobotanical and Medicinal Plants Studies
- Garlic and Onion Studies
- Medicinal Plants and Neuroprotection
- Ginkgo biloba and Cashew Applications
- Heavy Metals in Plants
- Genomics, phytochemicals, and oxidative stress
Universidade Federal do Piauí
2014-2024
Instituto Federal do Piauí
2014-2023
Centro de Tecnologias Estratégicas do Nordeste
2017
Grape pomace (Vitis vinifera L.), Benitaka variety, grown in the semiarid region of Northeast Brazil was evaluated relation to chemical composition, and content minerals functional properties. Its microbiological quality toxic potential, using Artemia salina sp, were also investigated. The results showed that flour obtained from these residues had below neutral pH (3.82), moisture (3.33g/100g), acidity (0.64g citric acid/100g), ash (4.65 g/100g). amount total dietary fiber (46.17g/100g)...
This study aimed to characterize the chemical composition, determine fatty acid profile, and quantify bioactive compounds present in guava seed powder (Psidium guajava L.). The resulted from seeds obtained pulp processing. agro-industrial red cv. paluma were used, they donated by a frozen fruit manufacturer. They contain varying amounts of macronutrients micronutrients, with high content total dietary fiber (63.94 g/100g), protein (11.19 iron (13.8 mg/100g), zinc (3.31 reduced calorie (182...
Casearia sylvestris (Salicaceae) is found in South America and presents antiulcerogenic, cytotoxic, antimicrobial, anti-inflammatory antihypertensive activities. To assess the vivo ex antitumor action of a fraction with casearins (FC) its main component - Casearin X-isolated from C. leaves. Firstly, Sarcoma 180 bearing Swiss mice were treated FC Cas X for 7 days. Secondly, BALB/c nude animals received hollow fibers colon carcinoma (HCT-116) or glioblastoma (SF-295) cells 4 On 5th day,...
Caatinga flora which are found in a poor Brazilian region contain substantial number of endemic taxa with biomedical and social importance for regional communities. This study examined the antioxidant cytotoxic potential 35 samples (extracts/fractions) from 12 species determined antiproliferative genotoxic action dichloromethane fraction Mimosa caesalpiniifolia stem bark (DC-Mca) on human vegetal cells. Samples were assessed chemopreventive ability, toxic effects Artemia salina shrimp as...
Bioactive compounds extracted from natural sources can benefit human health. The aim of this work was to determine total phenolic content and antioxidant activity in extracts Euphorbia tirucalli L. followed by identification quantification the compounds, as well their antibacterial activities. Antioxidant activities were determined DPPH ABTS(•+) assay. Identification performed using high-performance liquid chromatography (HPLC), antimicrobial verified agar dilution methods MIC values. Total...
RESUMOEste trabalho realizou um levantamento sobre o uso de plantas medicinais na cidade Picos-PI, identificou as cultivadas no horto pertencente ao Laboratório Fitoterápico Picos (LAFIPI), e analisou fitoterápicos dispensados pelo Programa Farmácia Viva triênio 2008-2010. Do total dos 750 entrevistados, 37,6% foram homens 62,4 % mulheres, dentre os quais a maioria não concluiu segundo grau (69,2%) 77,2% possuíam renda mensal até dois salários mínimos. Com relação consumo medicinais, 76,3%...
Mimosa caesalpiniifolia is a native plant of the Brazilian northeast, and few studies have investigated its chemical composition biological significance. This work describes identification first constituents in ethanolic extract fractions M. stem bark based on NMR, GC-qMS HRMS analyses, as well an assessment their cytotoxic activity. analysis showed fatty acid derivatives, triterpenes steroid substances confirmed identity compounds isolated from hexane fraction. Metabolite biodiversity...
Eleven phthalimide derivatives were evaluated with regards to their antiproliferative activity on tumor and normal cells possible toxic effects. Cytotoxic analyses performed against murine tumors (Sarcoma 180 B-16/F-10 cells) peripheral blood mononuclear (PBMC) using MTT Alamar Blue assays. Following, the investigation of cytotoxicity was executed by flow cytometry analysis antitumoral toxicological potential in vivo techniques. The molecules 3b, 3c, 4 5 revealed vitro Sarcoma 180, PBMC....
Phytochemical profile, antioxidant potential, total phenolic content and cytogenotoxic effect (Allium cepa test) were assessed in hexane (HE), ethyl acetate (EA) methanol (ME) extracts of Jatropha mollissima leaves. analysis revealed the presence triterpenes HE, which also observed conjunction with flavonoids EA. Saponins, catechins, phenols, tannins, flavonoids, flavones, flavonols xanthones present ME. The highest activity, determined by DPPH free radical scavenging ABTS assay, phenol...
Poincianella bracteosa has been widely used in folk medicine to treat catarrhal infections, diarrhea, and anemia; however, phytochemical toxicogenetic data are still lacking. The objective of this study was examine the antioxidant characteristics as well assess cytogenotoxicity antigenotoxicity hexane (HF), ether (EF) ethyl acetate (AF) fractions P. leaves using Allium cepa bioassay. Phytochemical analysis revealed presence saponins phenolic groups. EF fraction contained a higher content...
In this paper, we complement our previous study on the antiproliferative activity of Calea fruticosa (Asteraceae) by isolating compounds apigenin-4',7-dimethyl ether (1), budlein A (2), quercetin (3), and cichoriin (4) from plant's aerial parts. The these was evaluated 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method against human tumor cell lines. Compound 3 displayed moderate in three lines (HCT-116, PC-3, SF-295, with growth inhibition values 72.97, 74.55, 68.94%)...
Mauritia flexuosa L., traditionally known as “buriti”, exhibits chemoprotective properties including antioxidant, antithrombotic, and nutritional actions. The aim of this study was to examine the oral anti-inflammatory activity epicarp, mesocarp endocarp obtained from M. fruits using in vivo models verify physiological benefits. anti-edematogenic action determined phlogistic agents induce paw edema peritonitis. Pro-inflammatory cytokines, cell migration peritoneal cells, histological...
Commercialization of Mauritia flexuosa (buriti) fruits in Brazil is at an early stage. Herein, we evaluate the nutritional value pulp, peel and endocarp samples from buriti fruits, perform macroscopic microscopic evaluations analyze their physicochemical properties. Size mass, pH, sugar protein contents, soluble/insoluble fiber, total titratable acidity energy were analyzed. Mineral profiling was performed by dispersive X-ray fluorescence spectrometry, fatty acids phytosterols determined gas...
Safer analgesic drugs remain a hard challenge because of cardiovascular and/or gastrointestinal toxicity, mainly. So, this study evaluated in vivo the antiproliferative actions fraction with casearins (FC) from Casearia sylvestris leaves against human colorectal carcinomas and antihyperalgesic effects on inflammatory- or opiate-based pain relief oncologic Sarcoma 180 (S180)-bearing mice. Moreover, docking investigations binding among Casearin X NMDA(N-methyl-D-aspartate)-type glutamate...
Flavorings used in cookies, electronic cigarettes, popcorn, and breads contain approximately 30 chemical compounds, which makes it difficult to determine correlate signs symptoms of acute, subacute or chronic toxicity. The aim this study was characterize a butter flavoring chemically subsequently examine the vitro vivo toxicological profile using cellular techniques, invertebrates, lab mammals. For first time, ethyl butanoate found as main compound (97.75%) 24 h-toxicity assay employing...
ABSTRACTHeliotropium elongatum is used to treat inflammation, cough, and flu. This study aimed characterize the phytochemical profile determine total phenolic content (TPC), antioxidant cytogenotoxic activity of ethanolic extract (EE), fractions H. leaves. In analysis, organic acids, reducing sugars, flavonoids, saponins, anthraquinones, steroids/triterpenes, depsides/depsidones were detected in EE and/or (hexanic/FH, chloroformic/FC, ethyl acetate/FAE, hydromethanolic/FHM). The highest TPC...
Jua (juá in Portuguese) is an underexplored fruit from Brazil's northeast. This rich antioxidant substances. However, there a dearth of information about jua's bioactive potential. The present study evaluated two extraction methods (continuous agitation and ultrasound-assisted extraction-UAE) employed three different solvents (water, ethanol, acetone) to efficiently recover soluble phenolic compounds. Aqueous extracts obtained by UAE showed the highest total content (TPC) antiradical...