A5016147211- Research on Leishmaniasis Studies
- Synthesis and biological activity
- Olfactory and Sensory Function Studies
- Rural and Ethnic Education
- Inflammatory mediators and NSAID effects
- Insect Pest Control Strategies
- Fish biology, ecology, and behavior
- Plant biochemistry and biosynthesis
- Phytochemicals and Antioxidant Activities
- Piperaceae Chemical and Biological Studies
- Insect and Pesticide Research
- Bee Products Chemical Analysis
- Biochemical and Structural Characterization
- Phytochemistry and biological activity of medicinal plants
- Computational Drug Discovery Methods
- Plant-Derived Bioactive Compounds
- Antimicrobial Peptides and Activities
- Chromatography in Natural Products
- Neuropeptides and Animal Physiology
- Education Pedagogy and Practices
- Amazonian Archaeology and Ethnohistory
- Environmental Sustainability and Education
- Phytochemistry Medicinal Plant Applications
- Sesquiterpenes and Asteraceae Studies
- Essential Oils and Antimicrobial Activity
Universidade Federal do Piauí
2016-2024
Instituto Federal do Piauí
2016
Universidade Estadual do Piau
2016
ZONA Technology (United States)
2016
Ministério da Agricultura
2016
Secretaria do Meio Ambiente
2016
Abstract Chronic inflammation is triggered by numerous diseases such as osteoarthritis, Crohn's disease and cancer. The control of the pro-inflammatory process can prevent, mitigate and/or inhibit evolution these diseases. Therefore, anti-inflammatory drugs have been studied possible compounds to act in This paper proposes a computational analysis eugenol relation aspirin diclofenac analyzing ADMET profile interactions with COX-2 5-LOX enzymes, important enzymes signaling pathway processes....
Rose oxide (RO) is a monoterpene found in rose oil fragrances. This has been reported to possess anti-inflammatory activity, however, little known regarding its pharmacological activity. The present study was carried out evaluate antidepressant action and possible mechanisms of action. Analysis ADMET pharmacokinetic properties (absorption, distribution, metabolism, excretion toxicity) performed by computational prediction analysis. Behavioral tests were assess the interaction between central...
Safer analgesic drugs remain a hard challenge because of cardiovascular and/or gastrointestinal toxicity, mainly. So, this study evaluated in vivo the antiproliferative actions fraction with casearins (FC) from Casearia sylvestris leaves against human colorectal carcinomas and antihyperalgesic effects on inflammatory- or opiate-based pain relief oncologic Sarcoma 180 (S180)-bearing mice. Moreover, docking investigations binding among Casearin X NMDA(N-methyl-D-aspartate)-type glutamate...
Platonia insignis Mart, Clusiaceae, known as bacuri, is a species native to Brazil that, in studies with extract of the seed its fruit, showed antioxidant activity against free radicals. Products such properties may be great importance treatment peptic ulcers since this pathology associated inflammatory process caused by action Cyclodextrins are molecules capable forming inclusion complexes other molecules, affecting their physicochemical and improving pharmacokinetic characteristics. Thus,...
Matrikines are biologically active peptides generated from fragments fragmentation of extracellular matrix components (ECM) that functionally distinct the original full-length molecule. The matricryptic sites can be unmasked by ECM enzymatic degradation or multimerization, heterotypic binding, adsorption to other molecules, cell-mediated mechanical forces, exposure reactive oxygen species, denaturation, and others. Laminin α1-derived peptide (SIKVAV) is a bioactive derived laminin-111...
Historically this knowledge has been offered to the student of countryside without taking into account specificities life and job becoming only an adaptation teaching practiced in city rural school. That contributed just preserve establishment feed alienation countrysideman. This work aims propose alternative agribusiness pedagogical dynamics imposed on students countryside. It is intended development a methodology for chemical education promote dissemination scientific by who lives areas....
This study aims to assess the existence and rock art conservation status in Pedra doCamaleão. formation is located Serra do Cados city of Milton Brandão. Mid-north region state Piaui. It's intended characterize archaeological site where disclose their as well check types problems that threaten status. Another objective analyze, general, level knowledge population living close sites about cave paintings there are observe impacts presence ofthis on how it can contribute preservation. Beginning...
Abstract Species of Piperaceae are known by biological properties, including antiparasitic such as leishmanicidal, antimalarial and in the treatment schistosomiasis. The aim this work was to evaluate antileishmania activity, cytotoxic effect, macrophage activation patterns methanol (MeOH), hexane (HEX), dichloromethane (DCM) ethyl acetate (EtOAc) extract fractions from leaves Piper cabralanum C.DC. MeOH, HEX DCM inhibited Leishmanina amazonensis promastigote-like forms growth with a half...