- Antimicrobial Peptides and Activities
- Force Microscopy Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Biochemical and Structural Characterization
- Nanoparticles: synthesis and applications
- Polymer Surface Interaction Studies
- Advanced biosensing and bioanalysis techniques
- Conducting polymers and applications
- Lipid Membrane Structure and Behavior
- Nanocomposite Films for Food Packaging
- Molecular Junctions and Nanostructures
- Essential Oils and Antimicrobial Activity
- Ginkgo biloba and Cashew Applications
- Adhesion, Friction, and Surface Interactions
- Integrated Circuits and Semiconductor Failure Analysis
- Bacteriophages and microbial interactions
- Asian Studies and History
- Reformation and Early Modern Christianity
- Conservation, Biodiversity, and Resource Management
- Spectroscopy and Quantum Chemical Studies
- Pentecostalism and Christianity Studies
- Marine Biology and Environmental Chemistry
- Parasites and Host Interactions
- Studies on Chitinases and Chitosanases
- Polysaccharides Composition and Applications
University of Lincoln
2021-2025
Universidade do Porto
2015-2024
Rede de Química e Tecnologia
2015-2024
University of Lisbon
2008-2020
Universidade Federal do Piauí
2015-2019
Diocese of Brooklyn
2016-2018
University of Plymouth
2013
University of Portsmouth
2000-2011
University of Missouri
2010
Escola Superior de Saúde Egas Moniz
2008
Studies using infrared, (1)H and (13)C nuclear magnetic resonance, X-ray photoelectron spectroscopies differential scanning calorimetry support the hypothesis that hydrogen bonds, formed between carboxylic acid functionality of mucoadhesive material poly(acrylic acid) glycoprotein component mucus, play a significant role in process mucoadhesion. There are fewer H-bonded interactions components than within bulk pure agent. The pH medium influences structures both which, turn, determine nature...
Thermodynamic evidence for the selective Ca2+-mediated self-aggregation via carbohydrate−carbohydrate interactions of gold glyconanoparticles functionalized with disaccharides lactose (lacto-Au) and maltose (malto-Au), or biologically relevant trisaccharide Lewis X (LeX−Au), was obtained by isothermal titration calorimetry. The aggregation process also directly visualized atomic force microscopy. It shown in case that is a slow takes place decrease enthalpy 160 ± 30 kcal mol-1, while heat...
Silver nanoparticles have been shown to possess considerable antibacterial activity, but in vivo applications limited due the inherent, low, toxicity of silver. On other hand, silver could provide cutaneous protection against infection, their ability liberate ions via a slow release mechanism, and broad-spectrum antimicrobial action. Thus, this work, we describe development carboxymethyl cellulose-based hydrogel containing nanoparticles. The were prepared situ, utilizing two variants cashew...
Abstract Candida albicans is a major cause of human infections, ranging from relatively simple to treat skin and mucosal diseases systemic life-threatening invasive candidiasis. Fungal infections treatment faces three challenges: the limited number therapeutic options, toxicity available drugs, rise antifungal resistance. In this study, we demonstrate activity mechanism action peptides ToAP2 NDBP-5.7 against planktonic cells biofilms C. . Both were active cells; however, was more produced...
The significance of the Liftshitz/van der Waals, Lewis-acid, and Lewis-base contributors to total surface energy a homologous series poly(perfluoroalkyl methacrylate)s is discussed in terms molecular design features organization phenomena characterizing these polymeric compounds. study suggests that, requirements for low-surface-energy polymers, flexible backbone not an essential feature.
A photocatalytic approach was used to synthesize triangular nanoplates in aqueous solution. The synthesis is based on the reduction of a gold salt using tin(IV) porphyrin as photocatalyst, cetyltrimethylammonium bromide (CTAB) stabilizing agent, and triethanolamine (TEA) final electron donor. average edge length can be easily changed range 45–250 nm by varying concentration fine-tuning achieved CTAB. Study mechanism formation UV-vis transmission microscopy (TEM) shows that there first stage...
Magnetic force microscopy (MFM) is a very powerful technique, which can potentially be used to detect and localize the magnetic fields arising from nanoscopic domains, such as nanoparticles. However, in order achieve this, we must able use MFM discriminate between forces nanoparticles nonmagnetic other particles sample features. Unfortunately, show significant response even for nanoparticles, giving rise misleading results. The literature date lacks evidence detection of with control. In...
There are ethnopharmacological reports supporting the use of neem (Azadirachta indica A. Juss) leaf against bacterial and worm infections. However there is a lack studies about its effect on biofilm formation Schistosoma mansoni worms. This study in vitro effects ethanolic extract (Neem EE) Methicillin-resistant Staphylococcus aureus (MRSA) planktonic aggregation formation, S. Quantification Azadirachtin (AZA), thought to be one their main compounds related biological effects, was performed....
Schistosomiasis is a serious disease currently estimated to affect more that 207 million people worldwide. Due the intensive use of praziquantel, there increasing concern about development drug-resistant strains. Therefore, it necessary search for and investigate new potential schistosomicidal compounds. This work reports in vivo effect alkaloid epiisopiloturine (EPI) against adults juvenile worms Schistosoma mansoni. EPI was first purified its thermal behavior theoretical solubility...
Silver nanoparticles have been studied as an alternative for treatment of microbial infections and leishmaniasis, without promoting induction or parasite resistance. In this study, chitosan-based silver were synthesized from nitrate (AgNO 3 ), sodium borohydride a reducing agent, the biopolymer chitosan capping agent. The characterized by ultraviolet–visible, Fourier transform infrared, dynamic light scattering, zeta potential, atomic force microscopy, transmission electron microscope....
Aim: To test ocellatin peptides (ocellatins-PT2–PT6) for antibacterial and antibiofilm activities synergy with antibiotics against Pseudomonas aeruginosa. Materials & methods: Normal- checkerboard-broth microdilution methods were used. Biofilm studies included microtiter plate-based assays microscopic analysis by confocal laser scanning microscopy atomic force microscopy. Results: Ocellatins more active multidrug-resistant isolates of P. aeruginosa than susceptible strains. Ocellatin-PT3...
The aims of this study were to produce poly-ɛ-caprolactone lipid-core nanocapsules containing lycopene-rich extract from red guava (LEG), characterize those nanoparticles and evaluate their cytotoxic effects on human breast cancer cells. Lipid-core the (nanoLEG) produced by method interfacial deposition preformed polymer. characterized Dynamic Light Scattering (DLS), Polydispersity Index, Zeta Potential, pH, Encapsulation Efficiency, Nanoparticle Tracking Analysis (NTA), Atomic Force...