Bruno Iles

ORCID: 0000-0001-6844-7608
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About
Contact & Profiles
Research Areas
  • Ginkgo biloba and Cashew Applications
  • Parasites and Host Interactions
  • Bone health and treatments
  • Parasite Biology and Host Interactions
  • Antimicrobial Peptides and Activities
  • Helminth infection and control
  • Essential Oils and Antimicrobial Activity
  • Bioactive Compounds and Antitumor Agents
  • Polydiacetylene-based materials and applications
  • Metabolism, Diabetes, and Cancer
  • Enzyme Production and Characterization
  • Phytochemistry and Bioactivity Studies
  • Phytochemicals and Antioxidant Activities
  • Acupuncture Treatment Research Studies
  • Ion Channels and Receptors
  • Myofascial pain diagnosis and treatment
  • Polysaccharides and Plant Cell Walls
  • Trypanosoma species research and implications
  • Diabetic Foot Ulcer Assessment and Management
  • Phytochemistry and Biological Activities
  • Boron Compounds in Chemistry
  • Piperaceae Chemical and Biological Studies
  • Inflammatory mediators and NSAID effects
  • Biological Research and Disease Studies
  • Dermatological and COVID-19 studies

Institut des Sciences Biologiques
2025

Morpho (United States)
2025

Universidade de Brasília
2021-2025

Universidade Federal do Piauí
2017-2021

Universidade Federal do Delta do Parnaíba
2020-2021

Abstract Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study aimed to determine the primary structure and investigate peptides obtained from cutaneous amphibian, Leptodactylus vastus , a source molecules. The possessed amino acid sequences, GVVDILKGAAKDLAGH GVVDILKGAAKDLAGHLASKV, monoisotopic masses [M + H] ± = 1563.8 Da 2062.4 Da, respectively. molecules were characterized class ocellatins...

10.1038/s41598-020-59665-1 article EN cc-by Scientific Reports 2020-02-14

We aimed to determine whether carvacryl acetate acts as a TRPA1 receptor agonist and its effects against irinotecan (CPT-11) induced intestinal mucositis in mice.TRPA1 structure was obtained from protein databank, the 3D of determined. Appropriate binding conformations were discovered via automatic docking simulations. To effect vivo, mice treated with either DMSO 2%, CPT-11, followed by or HC-030031, antagonist, acetate. Jejunum samples taken structural, inflammatory antioxidant parameters...

10.1111/jphp.12818 article EN Journal of Pharmacy and Pharmacology 2017-09-21

Abstract Inflammation is the response of body to noxious stimuli such as infections, trauma, or injury. Experimental studies have shown that vanillic acid has anti‐inflammatory effects. The objective this study was investigate and antipyretic properties derivative acid, isopropyl vanillate (ISP‐VT), in mice. results indicated ISP‐VT reduced paw edema induced by carrageenan, dextran sulfate (DEX), compound 48/80, serotonin, bradykinin (BK), histamine (HIST), prostaglandin E2 (PGE2)....

10.1002/ddr.21546 article EN Drug Development Research 2019-05-21

Câncer é o nome dado a um conjunto de doenças complexas caracterizadas pelo crescimento descontrolado células anormais com alto potencial invasivo, sendo considerado dos maiores problema saúde pública mundial. A incidência câncer tem aumentado cada ano, mostrando relevância na realização pesquisas cujo objetivo seja tratamento do em suas diversas modalidades. Assim, este trabalho como realizar uma prospecção científica e tecnológica sobre aplicação nanopartículas alendronato sódio no câncer....

10.33448/rsd-v10i12.20491 article PT Research Society and Development 2021-09-21
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